Patents by Inventor Lisbet HAGLUND

Lisbet HAGLUND has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TREATMENT OF CARTILAGE AND DISC TISSUE PATHOLOGIES
    Publication number: 20210079040
    Abstract: An isolated polypeptide comprising a peptide selected from: i) DHX1SDNYT, wherein X1 is L or H (SEQ ID NO:3); ii) a conservative variant of i) iii) a fragment of i) or ii); wherein the conservative variant and/or fragment retains biological activity and the peptide is 15 or less amino acids as well as recombinant cells, and uses thereof.
    Type: Application
    Filed: April 6, 2020
    Publication date: March 18, 2021
    Inventors: Fackson MWALE, John ANTONIOU, Lisbet HAGLUND, Peter J. ROUGHLEY, Rahul GAWRI, Laura M. EPURE, Michael P. GRANT
  • METHODS AND COMPOSITIONS FOR TREATMENT OF CARTILAGE AND DISC TISSUE PATHOLOGIES
    Publication number: 20190375788
    Abstract: An isolated polypeptide comprising a peptide selected from: i) DHX1SDNYT, wherein X1 is L or H (SEQ ID NO:3); ii) a conservative variant of i) iii) a fragment of i) or ii); wherein the conservative variant and/or fragment retains biological activity and the peptide is 15 or less amino acids as well as recombinant cells, and uses thereof.
    Type: Application
    Filed: January 14, 2019
    Publication date: December 12, 2019
    Inventors: Fackson MWALE, John ANTONIOU, Lisbet HAGLUND, Peter J. ROUGHLEY, Rahul GAWRI, Laura M. EPURE, Michael P. GRANT
  • Methods and compositions for treatment of cartilage and disc tissue pathologies
    Patent number: 10202420
    Abstract: An isolated polypeptide comprising a peptide selected from: i) DHX1SDNYT, wherein X1 is L or H (SEQ ID NO:3); ii) a conservative variant of i) iii) a fragment of i) or ii); wherein the conservative variant and/or fragment retains biological activity and the peptide is 15 or less amino acids as well as recombinant cells, and uses thereof.
    Type: Grant
    Filed: August 27, 2014
    Date of Patent: February 12, 2019
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Fackson Mwale, John Antoniou, Lisbet Haglund, Peter J. Roughley, Rahul Gawri, Laura M. Epure, Michael P. Grant
  • METHODS AND COMPOSITIONS FOR TREATMENT OF CARTILAGE AND DISC TISSUE PATHOLOGIES
    Publication number: 20160207959
    Abstract: An isolated polypeptide comprising a peptide selected from: i) DHX1SDNYT, wherein X1 is L or H (SEQ ID NO:3); ii) a conservative variant of i) iii) a fragment of i) or ii); wherein the conservative variant and/or fragment retains biological activity and the peptide is 15 or less amino acids as well as recombinant cells, and uses thereof.
    Type: Application
    Filed: August 27, 2014
    Publication date: July 21, 2016
    Inventors: Fackson MWALE, John ANTONIOU, Lisbet HAGLUND, Peter J. ROUGHLEY, Rahul GAWRI, Laura M. EPURE, Michael P. GRANT
  • CHONDROADHERIN FRAGMENTS AS INDICATORS OF INTERVERTEBRAL DISC DEGENERATION
    Publication number: 20160091500
    Abstract: The present disclosure concern fragments of the chondroadherin (CHAD) polypeptide which are generated during the proteolytic cleavage of the third leucine repeat motif of the CHAD polypeptide. Such fragments are generated and thus associated with the onset and progression of intervertebral disc degeneration and can be used to assess the risk of a subject to develop intervertebral disc degeneration or to determine if the subject is afflicted by intervertebral disc degeneration. The fragments can also be used to screen for potential therapeutic agents for preventing, treating and/or alleviating the symptoms associated with intervertebral disc degeneration.
    Type: Application
    Filed: May 13, 2014
    Publication date: March 31, 2016
    Inventors: Lisbet HAGLUND, Peter ROUGHLEY, Bashar ALKHATIB, Jean OUELLET, Patrick ÖNNERFJORD