Abstract: An ophthalic device and system for measuring and controlling relative fluid pressure inside an ocular globe includes a surgical instrument which is adapted to penetrate the ocular globe. A fluid pressure transducer is mounted on the instrument so that when the instrument penetrates the ocular globe the transducer is located adjacent to an opening that communicates with the interior of the globe so that it can react to pressure changes in the fluid therein and generate signals in response to changes in the pressure of the fluid. The signal is transmitted external of the instrument to a control system which is operatively connected to the transducer for first receiving signals from the transducer and the controlling a fluid supply system in response to signals according to a predetermned set of instructions. The control system is connected to a closed loop feed system in which fluid is continuously circulated.

Abstract: An ophthalmic device and system for measuring and controlling relative pressure of fluid inside an ocular globe includes a surgical instrument which is adapted to penetrate the ocular globe. A fluid pressure transducer is mounted on the instrument so that, when the instrument penetrates the ocular globe, the transducer is located adjacent to an opening that communicates with the interior of the globe so that it can react to pressure changes in the fluid therein and generate signals in response to pressure changes in the fluid. The signal is transmitted external of the instrument to a pump or other fluid transfer device which is operatively connected to the transducer for first receiving signals and then supplying or removing fluid from the ocular globe in response to the signals according to a predetermined set of instructions. The pump is connected to a closed loop in which fluid is continuously circulated.

Abstract: An ophthalmic device and system for measuring relative pressure of fluid inside an ocular globe includes an elongated surgical instrument which is adapted to penetrate the ocular globe. A fluid pressure transducer is mounted on the instrument in a position to communicate with fluid inside the ocular globe and generate signals in response to pressure changes in the fluid. The signal is transmitted external of the instrument to a pump or other fluid transfer device which is operatively connected to the transducer for receiving the signals and supplying or removing fluid from the ocular globe in response to predetermined signals. A conduit is operatively connected to the fluid transfer device and adapted to communicate with the interior of the ocular globe through which fluid can flow between the fluid transfer device and the ocular globe.

Abstract: This invention relates to the treatment of wounded ocular tissue by the topical application of collagen cross-linking inhibitors to the tissue in order to reduce the cross-linking of collagen fibrils in the wounded tissue.