Patents by Inventor Lucia Dobrescu

Lucia Dobrescu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detoxified E. coli neurotoxin, preparation thereof and immunological preparations containing it
    Patent number: 4465665
    Abstract: Detoxified but still immunogenic E. coli neurotoxin is prepared by bringing E. coli neurotoxin into contact with glutaraldehyde in mild operative conditions, the reaction being stopped where no more than 90% of the neurotoxin are inactivated.The obtained detoxified neurotoxin is valuable for immunizing piglets against oedema disease.
    Type: Grant
    Filed: March 4, 1982
    Date of Patent: August 14, 1984
    Assignee: Smithkline-Rit
    Inventor: Lucia Dobrescu
  • Vaccines against oedema disease of piglets
    Patent number: 4136181
    Abstract: Vaccines against oedema disease of piglets comprising an effective amount of E. coli neurotoxin isolated from a culture of an E. coli serotype which is capable of causing piglet oedema disease and adsorbed on an adjuvant. The vaccines are administered by intramuscular or subcutaneous route.
    Type: Grant
    Filed: December 29, 1977
    Date of Patent: January 23, 1979
    Assignee: Recherche et Industrie, Therapeutiques, RIT
    Inventors: Lucia Dobrescu, Constant Huygelen, Frans Van Wijnendaele
  • Pre-farrowing pregnant sow piglet colibacillosis vaccines and process for their administration to pregnant sows before farrowing
    Patent number: 4053584
    Abstract: Piglet colibacillosis vaccine for intramuscular or subcutaneous administration to pregnant sows comprising cell-free heat labile (LT) E. coli enterotoxin with an adjuvant and the method for preventing piglet colibacillosis consisting in administering said vaccine to pregnant sows from 3 to 6 weeks before farrowing.
    Type: Grant
    Filed: March 29, 1976
    Date of Patent: October 11, 1977
    Assignee: Recherche et Industrie Therapeutiques
    Inventors: Lucia Dobrescu, Constant Huygelen