Abstract: A method of forming shallow trench isolation on a substrate using a gas cluster ion beam (GCIB) is described. The method comprises generating a GCIB, and irradiating the substrate with the GCIB to form a shallow trench isolation structure by depositing a dielectric layer in at least one region on the substrate.

Abstract: The invention relates to a method for determining DNA integrity in microorganisms and to a kit for evaluating DNA integrity in same. Since cell death results in DNA fragmentation, the inventive method can be used to determine DNA fragmentation levels in microorganisms clearly, simply, quickly and precisely.

Abstract: The invention relates to a method for marking a digital document, especially a digital image, with a digital watermark for the purpose of manipulation recognition while inserting an integrity information and at least one multibit message.

Abstract: It is a seat that basically consists of a structural cover that is split into compartments that, in the specific case of a sofa, has different cavities for the backrest, seat, armrest and other parts of the sofa, in such a way that bags filled with a lightweight material can be fitted into and adjusted inside these cavities, so that these bags are really the elements that serve to reinforce the sofa as a whole, thus obtaining a low-cost and lightweight product that is easy to transport because of its slight volume as a result of it being possible to dismantle it before transporting it, which sets it apart from most conventional sofas, which have to be moved in their completely assembled form. The bags can be composed of a single compartment or several, in which case each compartment may in turn be filled with different materials in order to obtain different degrees of flexibility.

Abstract: The invention relates to a form tool for injection-molding molded articles (6), especially PET parisons. The form tool comprises a base plate (2) and a stripper plate (3) having a slide (4). A plurality of separable male mold cones (5, 5?) is provided on the slide (4). For removing the parisons (6), the male mold cones (5, 5?) are completely opened using a hydraulic drive (12) instead of an inclined drag element.

Abstract: The invention relates to a process for manufacturing flat glass rich in lead oxide, comprising the continuous floating, in a float plant with a neutral gaseous atmosphere, of a glass comprising at least 30% lead oxide by weight on a bath of molten metal having a higher density than that of the glass. The invention allows flat glass rich in lead, useful for protection against X-rays, to be produced.

Abstract: The invention provides antitumour compounds of formula (I), wherein R1 is an aromatic substituent; R2 is hydrogen or a substituent when the dotted line is absent, or R2 is absent when the dotted line represents a bond to give a double bond between the nitrogen which bears R2 and the carbon which bears R3; R3 is an oxo group ?O when the dotted line is absent or is a substituent when the dotted line represents a bond to give a double bond between the nitrogen bearing R2 and the carbon bearing R3; R4 is hydrogen or a substituent; and pharmaceutically acceptable salts thereof.

Abstract: The present invention describes a method for the determination of DNA fragmentation in animal sperm. It particularly refers to a procedure to evaluate the integrity of the chromatin/DNA of the sperm by means of a treatment of the sample with a denaturing solution followed, optionally by a stain; a subsequent treatment with a lysis solution that does not contain a protein denaturing detergent, followed, optionally, by a stain; and an evaluation of the integrity of the chromatin/DNA. The present invention also refers to a Kit to evaluate the quality of the sperm of animals which includes a DNA denaturing solution and a lysis solution that does not contain a protein denaturing detergent.

Abstract: Naturally occurring stolonoxide compounds, and derivatives thereof, have antitumor activity.

Abstract: Disclosed is a coinjection nozzle for a two-component injection molding tool, which is used for producing parisons. The inventive nozzle comprises a nozzle holder (1) and an nozzle tip (4) that is mounted therein. A shut-off needle (11) is directed within a needle guide (3) at least in a top portion (K) of the needle tip (4). An additional nozzle sleeve (2) is disposed between the needle guide (3) and the nozzle tip (4). A first tubular delivery duct (A) extends between the nozzle sleeve (2) and the nozzle tip (4) while a second tubular delivery duct (B) extends between the nozzle sleeve (2) and the needle guide (3). The needle guide (3) is provided with a conical needle-guiding head (3a) located in the top portion (K) of the nozzle. A throat is provided in the first tubular delivery duct (A) in the area (E) of the nozzle. The needle-guiding head (3a) and the nozzle sleeve (2) are shaped in such a way that the second tubular delivery duct (B) narrows in a final area so as to form a shear edge (F).

Abstract: The present invention is related to the field of immunology and more specifically with immunotherapeutic combinations used for controlling growth and/or cell proliferation of tumors. By means of the present invention a therapeutic effect against tumors is observed by the combination of idiotypic vaccines whose principle active is an anti-ganglioside antibody (Ab1), with idiotypic vaccines whose principle active is anti-idiotype antibody (Ab2) obtained against an anti-ganglioside antibody, or vaccines whose principle active is one or more gangliosides. Combinations of these vaccines are described that cause a synergic therapeutic effect against tumors. The referred combinations can be applied to patients in different clinical conditions of tumors that express gangliósidos.

Abstract: A synchronous hydraulic pump for dishwashers and washing machines comprising a synchronous motor (1), an impeller (2) coaxial to said synchronous motor (1) and a hydraulic body (3), said impeller (2) being housed in said hydraulic body (3) and the hydraulic body (3) having an inlet pipe (4) and an outlet pipe (5). The pump also comprises at least one piece (8) adjacent to the impeller (2), said piece (8) having a projection (9) pointing at the outlet pipe (5), in such a way that said projection (9) acts as a guider directing the flow circulating inside the hydraulic body (3) towards the outlet pipe (5).

Abstract: The invention provides antitumour compounds of formula (I), wherein R1 is an aromatic substituent; R2 is hydrogen or a substituent when the dotted line is absent, or R2 is absent when the dotted line represents a bond to give a double bond between the nitrogen which bears R2 and the carbon which bears R3; R3 is an oxo group ═O when the dotted line is absent or is a substituent when the dotted line represents a bond to give a double bond between the nitrogen bearing R2 and the carbon bearing R3; R4 is hydrogen or a substituent; and pharmaceutically acceptable salts thereof.

Abstract: Citreamicins possess useful antitumor activity. Typically they are of formula, wherein R1 is selected from the group consisting of COCH2CH(CH3)2, COCH3 or H when R2 is CH3, or wherein R1 is COCH2CH(CH3)2, and R2 is H.

Abstract: Compounds of the following formula: wherein all variables are as defined in the specification. The compounds have cytotoxic properties and can therefore be used in the treatment of malignant tumors.

Abstract: Naturally occuring stolonoxide compounds, and derivatives thereof, have antitumour activity. Typical compounds are of the formula (I) or a derivative thereof.

Abstract: The invention provides compounds of formula (I) wherein R1 represents a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms, a hydroxy group, an alkoxy group having from 1 to 6 carbon atoms, a halogen atom, a nitro group, an amino group, a monoalkylamino group wherein the alkyl moiety has from 1 to 6 carbon atoms, a dialkylamino group wherein each alkyl moiety may be the same or different and each has from 1 to 6 carbon atoms, a dialkoxyamino group wherein each alkoxy moiety may be the same or different and each has from 1 to 6 carbon atoms, an alkanoyalmino group having from 1 to 20 carbon atoms or an alkanesulfonylamino group having from 1 to 6 carbon atoms; R2 represents a hydrogen atom or an alkyl group having from 1 to 6 carbon atoms; and R3 represents a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms or an alkoxy group having from 1 to 6 carbon atoms; and pharmaceutically acceptable salts thereof.

Abstract: “A synchronous hydraulic pump for dishwashers and washing machines comprising a synchronous motor (1), an impeller (2) coaxial to said synchronous motor (1) and a hydraulic body (3), said impeller (2) being housed in said hydraulic body (3) and the hydraulic body (3) having an inlet pipe (4) and an outlet pipe (5). The pump also comprises at least one piece (8) adjacent to the impeller (2), said piece (8) having a projection (9) pointing at the outlet pipe (5), in such a way that said projection (9) acts as a guider directing the flow circulating inside the hydraulic body (3) towards the outlet pipe (5).

Abstract: Compounds of formula (I), wherein X is selected from the group consisting of O, and NR3, where R3 represents a lower alkyl group; Y is selected from the group consisting of CH and N; R1 and R2 are independently selected from the group consisting of NH2, NHR4 and NR52, where R4 and R5 each represent a lower alkyl group, or R1 and R2 together represent a cycle selected from (a), (b) and (c), wherein R6, R7 and R8 are independently selected from the group consisting of hydrogen atoms, lower alkyl groups, hydroxy groups and lower alkoxy groups; and Z is selected from the group consisting of O.