Patents by Inventor Mads Eskelund Bjørnvad
Mads Eskelund Bjørnvad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9493730Abstract: The present invention relates to cleaning compositions comprising variants of an alpha-amylase having improved stability to chelating agents relative to its parent enzyme and cleaning processes comprising such compositions.Type: GrantFiled: February 10, 2011Date of Patent: November 15, 2016Assignee: The Procter & Gamble CompanyInventors: Michelle Meek, Philip Frank Souter, Lindsay Suzanne Bewick, Allan Svendsen, Annette Helle Johansen, Mads Eskelund Bjoernvad, Frank Winther Rasmussen, Michael Skjoet, Signe Eskildsen Larsen, Jens Oebro, Svend Kaasgaard, Lars Beier
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Patent number: 8871441Abstract: The invention provides methods of screening a microbial host cell for a property of interest in a microfluidic device, the method comprising the steps of: a) transforming a d-alanine racemase-deficient microbial host cell with a polynucleotide construct comprising: i) one or more polynucleotide region providing the property of interest when present in the host cell, and ii) at least one polynucleotide region complementing the d-alanine racemase deficiency when present in the host cell; and b) screening the transformed host cell for the property of interest in the microfluidic device in the absence of externally provided d-alanine.Type: GrantFiled: August 14, 2009Date of Patent: October 28, 2014Assignee: Novozymes A/SInventors: Thomas Lenhard, Mads Eskelund Bjoernvad, Poul Erik Pedersen
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Publication number: 20110212876Abstract: The present invention relates to cleaning compositions comprising variants of an alpha-amylase having improved stability to chelating agents relative to its parent enzyme and cleaning processes comprising such compositions.Type: ApplicationFiled: February 10, 2011Publication date: September 1, 2011Inventors: Michelle MEEK, Philip Frank Souter, Lindsay Suzanne Bewick, Allan Svendsen, Annette Helle Johansen, Mads Eskelund Bjoernvad, Frank Winther Rasmussen, Michael Skjoet, Signe Eskildsen Larsen, Jens Oebro, Svend Kaasgaard, Lars Beier
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Publication number: 20110159511Abstract: The invention provides methods of screening a microbial host cell for a property of interest in a microfluidic device, the method comprising the steps of: a) transforming a d-alanine racemase-deficient microbial host cell with a polynucleotide construct comprising: i) one or more polynucleotide region providing the property of interest when present in the host cell, and ii) at least one polynucleotide region complementing the d-alanine racemase deficiency when present in the host cell; and b) screening the transformed host cell for the property of interest in the microfluidic device in the absence of externally provided d-alanine.Type: ApplicationFiled: August 14, 2009Publication date: June 30, 2011Inventors: Thomas Lenhard, Mads Eskelund Bjoernvad, Poul Erik Pedersen
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Patent number: 7919298Abstract: The invention provides polypeptides obtained by introducing mutations in one or more regions identified in a parent lipase. The polypeptides of the present invention have surprisingly been found to have a low specific activity towards short chain fatty acids leading to a reduced odor generation and an increased BR over the lipases known in the art.Type: GrantFiled: February 26, 2009Date of Patent: April 5, 2011Assignee: Novozymes A/SInventors: Jesper Vind, Jurgen Carsten Franz Knotzel, Kim Borch, Allan Svendsen, Thomas Hoenger Callisen, Debbie Yaver, Mads Eskelund Bjoernvad, Peter Kamp Hansen
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Patent number: 7611882Abstract: Detergent composition comprising a surfactant and a pectate lyase (EC 4.2.2.2) enzyme en-coded by a DNA sequence endogeneous to a strain of Bacillus subtilis or a stabilized variant thereof provides superior cleaning and stain removal.Type: GrantFiled: May 14, 2002Date of Patent: November 3, 2009Assignee: Novozymes A/SInventors: Mads Eskelund Bjørnvad, Martin Schülein, Torben Henriksen, legal representative, Vibeke Skovgaard Nielsen, Johan Smets, Carsten Andersen, Thomas Thisted
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Publication number: 20090221033Abstract: The invention provides polypeptides obtained by introducing mutations in one or more regions identified in a parent lipase. The polypeptides of the present invention have surprisingly been found to have a low specific activity towards short chain fatty acids leading to a reduced odor generation and an increased BR over the lipases known in the art.Type: ApplicationFiled: February 26, 2009Publication date: September 3, 2009Applicant: Novozymes A/SInventors: Jesper Vind, Jurgen Carsten Franz Knotzel, Kim Borch, Allan Svendsen, Thomas Hoenger Callisen, Debbie Yaver, Mads Eskelund Bjoernvad, Peter Kamp Hansen
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Patent number: 7273745Abstract: The present invention relates to pectate lyases comprising the amino acid sequence Asn Leu Asn Ser Arg Val Pro (NLNSRVP) (amino acids 236-242 of SEQ ID NO: 2) belonging to Family 1 of polysaccharide lyases have good performance in industrial processes under neutral or alkaline conditions such as laundering and textile processing. The pectate lyase may be derivable from Bacillus species.Type: GrantFiled: November 28, 2006Date of Patent: September 25, 2007Assignee: Novozymes A/SInventors: Lene Nonboe Andersen, Hanne Dela, legal representative, Niels Erik Krebs Lange, Mads Eskelund Bjørnvad, Søren Møller, Sanne O. Schrøder Glad, Markus Sakari Kauppinen, Kirk Schnorr, Lars Kongsbak, Martin Schülein, deceased
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Patent number: 7256030Abstract: An enzyme exhibiting endo-?-1,4-glucanase activity which belongs to family 9 of glycosyl hydrolases is obtainable from or endogeneous to a strain belonging to the genus Bacillus such as Bacillus licheniformis, ATCC 14580; an isolated polynucleotide (DNA) molecule encoding an enzyme or enzyme core (the catalytically active domain of the enzyme) exhibiting endo-?-1,4-glucanase activity selected from (a) polynucleotide molecules comprising a nucleotide sequence as shown in SEQ ID NO:1 from nucleotide 76 to nucleotide 1455 or from nucleotide 76 to nucleotide 1941, (b) polynucleotide molecules that encode a polypeptide being at least 75% identical to the amino acid sequence of SEQ ID NO:2 from amino acid residue 26 to amino acid 485 or from amino acid residue 26 to amino acid residue 646, and (c) degenerate nucleotide sequences of (a) or (b), the expressed endoglucanase enzyme being useful in various industrial applications.Type: GrantFiled: May 23, 2000Date of Patent: August 14, 2007Assignee: Novozymes A/SInventors: Martin Schülein, Mads Eskelund Bjørnvad
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Patent number: 7041488Abstract: An enzyme exhibiting endo-beta-1,4-glucanase activity (EC 3.2.1.4), which is selected from one of a) a polypeptide encoded by the DNA sequence of positions 1 to 2322 of SEQ ID NO:1,b) a polypeptide produced by culturing a cell comprising the sequence of SEQ ID NO:1 under conditions wherein the DNA sequence is expressed; c) an endo-beta-1,4-glucanase enzyme having a sequence of at least 97% identity to the amino acid sequence of position 1 to position 773 of SEQ ID NO:2, and fragments thereof exhibitng endo-beta-1,4-glucanase activity, and d) a polypeptide having endo-beta-1,4-glucanase activity that is encoded by a polynucleo-tide that hybridizes with the nucleotide sequence shown in positions 1-2322 of SEQ ID NO:1, is useful for detergent and textile applications.Type: GrantFiled: June 6, 2002Date of Patent: May 9, 2006Assignee: Novozymes A/SInventors: Helle Outtrup, Torben Henriksen, Mads Eskelund Bjørnvad, Martin Schülein
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Patent number: 6677147Abstract: The present invention relates to pectate lyases comprising the amino acid sequence Asn Leu Asn Ser Arg Val Pro (NLNSRVP) (SEQ ID NO: 2) belonging to Family 1 of polysaccharide lyases have good performance in industrial processes under neutral or alkaline conditions such as laundering and textile processing. The pectate lyase may be derivable from Bacillus species.Type: GrantFiled: February 7, 2002Date of Patent: January 13, 2004Assignee: Novozymes A/SInventors: Lene Nonboe Andersen, Martin Schülein, Niels Erik Krebs Lange, Mads Eskelund Bjørnvad, Søren Møller, Sanne O. Schroder Glad, Markus Sakari Kauppinen, Kirk Schnorr, Lars Kongsbak
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Patent number: 6630340Abstract: The present invention relates to xyloglucanases belonging to family 5 of glycosyl hydrolases are derived from strains of Paenibacillus, especially from strains of Paenibacillus pabuli. The xyloglucanases show high performance in conventional liquid detergent compositions.Type: GrantFiled: March 1, 2001Date of Patent: October 7, 2003Assignee: Novozymes A/SInventors: Reinhard Wilting, Mads Eskelund Bjørnvad, Markus Sakari Kauppinen, Martin Schulein
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Patent number: 6630342Abstract: The present invention provides methods for high-temperature biopreparation of cellulosic fibers by contacting the fibers with pectin-degrading enzymes, preferably thermostable, alkaline, divalent cation-independent pectate lyases, under conditions compatible with scouring and bleaching technologies.Type: GrantFiled: February 20, 2001Date of Patent: October 7, 2003Assignee: Novozymes A/SInventors: Niels Erik Krebs Lange, Lars Kongsbak, Martin Shülein, Mads Eskelund Bjørnvad, Philip Anwar Husain
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Patent number: 6566114Abstract: Novel mannanases comprising e.g. an amino acid sequence as shown in positions 31-330 of SEQ ID NO:2 or their homologues may be derived from e.g. Bacillus sp. I633, or may be encoded by polynucleotide molecules comprising a nucleotide sequence as shown in SEQ ID NO: 1 from nucleotide 91 to nucleotide 990, polynucleotide molecules that encode a polypeptide that is at least 65% identical to the amino acid sequence of SEQ ID NO: 2 from amino acid residue 31 to amino acid residue 330, or degenerate nucleotide sequences thereof. The mannanases are alkaline and are useful e.g. in cleaning compositions, in a fracturing fluid useful to fracture a subterranean formation, for modifying plant material, and for treatment of cellulosic fibers.Type: GrantFiled: June 24, 1999Date of Patent: May 20, 2003Assignee: Novozymes, A/SInventors: Markus Sakari Kauppinen, Martin Schülein, Kirk Schnorr, Lene Nonboe Andersen, Mads Eskelund Bjørnvad
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Patent number: 6429000Abstract: Pectin degrading enzymes derived from or endogeneous to Bacillus licheniformis or other Bacillus species which are at least 99% homologous to Bacillus licheniformis based on aligned 16S rDNA sequences have optimum activity at pH higher than 8. The pectin degrading enzymes belongs to the enzyme classes pectate lyases (EC 4.2.2.2), pectin lyases (EC 4.2.2.10) and polygalacturonases (EC 3.2.1.15) and are useful in industrial processes under alkaline conditions such as in textile processing and as an active ingredient eg in laundry detergents and hard surface cleaning products.Type: GrantFiled: September 26, 2000Date of Patent: August 6, 2002Assignee: Novozymes A/SInventors: Lene Nonboe Andersen, Martin Schülein, Niels Erik Krebs Lange, Mads Eskelund Bjørnvad, Kirk Schnorr
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Patent number: 6399351Abstract: A novel pectate lyase belonging to a novel family of polysaccharide lyases has good performance in industrial processes under neutral or alkaline conditions such as laundering and textile processing. The pectate lyase may be derivable from Bacillus species.Type: GrantFiled: March 15, 2000Date of Patent: June 4, 2002Assignee: Novozymes A/SInventors: Mads Eskelund Bjørnvad, Jens Toenne Andersen, Kirk Schnorr, Martin Schülein, Lars Kongsbak
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Patent number: 6368843Abstract: A novel group of pectate lyases comprising the amino acid sequence Asn Leu Asn Ser Arg Val Pro (NLNSRVP) belonging to Family 1 of polysaccharide lyases have good performance in industrial processes under neutral or alkaline conditions such as laundering and textile processing. The pectate lyase may be derivable from Bacillus species.Type: GrantFiled: October 23, 2000Date of Patent: April 9, 2002Assignee: Novozymes A/SInventors: Lene Nonboe Andersen, Martin Schülein, Niels Erik Krebs Lange, Mads Eskelund Bjørnvad, Søren Møller, Sanne O. Schrøder Glad, Markus Sakari Kauppinen, Kirk Schnorr, Lars Kongsbak
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Patent number: 6331426Abstract: The invention relates to a method for modifying animal feed, in particular animal feed containing plant material such as soybean, by adding to the animal feed at least one galactanase enzym, to a method for obtaining a DNA sequence encoding a galactanase enzyme or a portion thereof, and to isolated polynucleotide molecules encoding polypeptides having galactanase activity.Type: GrantFiled: February 11, 2000Date of Patent: December 18, 2001Assignee: Novozymes A/SInventors: Mads Eskelund Bjørnvad, Ib Groth Clausen, Martin Schülein, Lisbeth Bech, Peter Rahbek Østergaard, Carsten Sjøholm
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Patent number: 6258590Abstract: The present invention provides methods for higha-temperature biopreparation of cellulosic fibers by contacting the fibers with pectin-degrading enzymes, preferably thermostable, alkaline, divalent cation-independent pectate lyases, under conditions compatible with scouring and bleaching technologies.Type: GrantFiled: November 2, 1998Date of Patent: July 10, 2001Assignees: Novozymes A/S, Novozymes North AmericaInventors: Niels Erik Krebs Lange, Lars Kongsbak, Martin Shülein, Mads Eskelund Bjørnvad, Philip Anwar Husain
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Patent number: 6207436Abstract: An enzyme preparation comprising an enzyme having endo-&bgr;-1,4-glucanase activity obtainable from or endogeneous to a strain belonging to the genus Saccharothrix such as Saccharothrix australiensis, IFO 14444; an isolated polynucleotide (DNA) molecule encoding an enzyme or enzyme core (the catalytically active domain of the enzyme) exhibiting endo-&bgr;-1,4-glucanase activity selected from (a) polynucleotide molecules comprising a nucleotide sequence as shown in SEQ ID NO:1 from nucleotide 676 to nucleotide 1470, (b) polynucleotide molecules that encode a polypeptide that is at least 80% identical to the amino acid sequence of SEQ ID NO:2 from amino acid residue 226 to amino acid residue 490, and (c) degenerate nucleotide sequences of (a) or (b), the expressed endoglucanase and the enzyme preparation being useful in a detergent or fabric softener composition or in the textile industry for improving the properties of cellulosic fibres or fabric or for providing a stone-washed look of denim.Type: GrantFiled: July 2, 1998Date of Patent: March 27, 2001Assignee: NovoNordisk A/SInventors: Mads Eskelund Bjørnvad, Mariko Hatakeyama, Martin Schülein, Jack Bech Nielsen