Patents by Inventor Magali Jeannine Blandine Maillet

Magali Jeannine Blandine Maillet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spiro-cyclic compounds useful as anti-inflammatory agents
    Patent number: 7199125
    Abstract: The present invention is directed to compounds having the formula (I): useful in treating inflammatory and immune diseases, in which K and L are independently, O or S; Q is —C(?O)— or optionally substituted C1-6alkylene; Ar is optionally-substituted aryl or heteroaryl; J1, J2, J3 and Y are selected so that ring A is a five-to-six membered optionally-substituted cycloalkenyl or heterocyclo ring having 0 to 2 nitrogen heteroatoms; R1 is N or C(R9); and R2, and R3, are as defined in the specification.
    Type: Grant
    Filed: October 1, 2004
    Date of Patent: April 3, 2007
    Assignees: Bristol-Myers Squibb Company, Cerep SA
    Inventors: T. G. Murali Dhar, Edwin Iwanowicz, Michele Launay, Dominique Potin, Magali Jeannine Blandine Maillet, Eric Nicolai
  • Spiro-hydantoin compounds useful as anti-inflammatory agents
    Patent number: 7078420
    Abstract: Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates, enantiomers, and diastereomers, and prodrugs thereof, are useful as inhibitors of LFA-1/ICAM and as anti-inflammatory agents, wherein L and K are O or S; Z is N or CR4b; Ar is an optionally-substituted aryl or heteroaryl; G is a linker attached to T or M or is absent; J, M and T are selected to define a three to six membered saturated or partially unsaturated non-aromatic ring; and R2, R4a, R4b, and R4c are as defined in the specification.
    Type: Grant
    Filed: May 24, 2004
    Date of Patent: July 18, 2006
    Assignees: Bristol-Myers Squibb Company, Cerep SA
    Inventors: T. G. Murali Dhar, Dominique Potin, Magali Jeannine Blandine Maillet, Michele Launay, Eric Antoine Nicolai, Edwin J. Iwanowicz
  • Spiro-hydantoin compounds useful as anti-inflammatory agents
    Patent number: 6977267
    Abstract: Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates, enantiomers, and diastereomers, and prodrugs thereof, are useful as inhibitors of LFA-1/ICAM and as anti-inflammatory agents, wherein L and K are O or S; Z is N or CR4b; Ar is an optionally-substituted aryl or heteroaryl; G is a linker attached to T or M or is absent; J, M and T are selected to define a three to six membered saturated or partially unsaturated non-aromatic ring; and R2,R4a, R4b, and R4c are as defined in the specification.
    Type: Grant
    Filed: October 1, 2002
    Date of Patent: December 20, 2005
    Assignees: Bristol-Myers Squibb Company, CEREP SA
    Inventors: T. G. Murali Dhar, Dominique Potin, Magali Jeannine Blandine Maillet, Michele Launay, Eric Antoine Nicolai, Edwin J. Iwanowicz
  • Hexahydro-benzimidazolone compounds useful as anti-inflammatory agents
    Patent number: 6974815
    Abstract: The present invention is directed to compounds having the formula (I): useful in treating inflammatory and immune diseases, in which K is O or S; Q is —C(?O)— or optionally substituted C1-4alkylene; Ar is optionally-substituted aryl or heteroaryl; J1, J2, J3, and Y are selected so that ring A is a five-to-six membered optionally-substituted cycloalkenyl or heterocyclo ring having 0 to 2 nitrogen heteroatoms; Z is N or C(R9); and R1, R2, R3 and R9 are as defined in the specification.
    Type: Grant
    Filed: October 9, 2003
    Date of Patent: December 13, 2005
    Assignees: Bristol-Myers Squibb Company, Cerep SA
    Inventors: T G. Murali Dhar, Dominique Potin, Magali Jeannine Blandine Maillet, Michele Launay, Eric Antoine Nicolai, Edwin J. Iwanowicz
  • Spiro-hydantoin compounds useful as anti-inflammatory agents
    Publication number: 20040259897
    Abstract: Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates, enantiomers, and diastereomers, and prodrugs thereof, 1
    Type: Application
    Filed: June 16, 2004
    Publication date: December 23, 2004
    Inventors: T.G. Murali Dhar, Dominique Potin, Magali Jeannine Blandine Maillet, Michele Launay, Eric Antoine Nicolai, Edwin J. Iwanowicz
  • Spiro-hydantoin compounds useful as anti-inflammatory agents
    Publication number: 20040248920
    Abstract: Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates, enantiomers, and diastereomers, and prodrugs thereof, 1
    Type: Application
    Filed: May 24, 2004
    Publication date: December 9, 2004
    Inventors: T.G. Murali Dhar, Dominique Potin, Magali Jeannine Blandine Maillet, Michele Launay, Eric Antoine Nicolai, Edwin J. Iwanowicz
  • Hexahydro-benzimidazolone compounds useful as anti-inflammatory agents
    Publication number: 20040116467
    Abstract: The present invention is directed to compounds having the formula (I): 1
    Type: Application
    Filed: October 9, 2003
    Publication date: June 17, 2004
    Inventors: T.G. Murali Dhar, Dominique Potin, Magali Jeannine Blandine Maillet, Michele Launay, Eric Antoine Nicolai, Edwin J. Iwanowicz
  • Hydantoin compounds useful as anti-inflammatory agents
    Patent number: 6710064
    Abstract: Compounds having the formula (I): and pharmaceutically-acceptable salts thereof, are useful for treating inflammatory or immune diseases, in which A is a four to seven membered heterocyclic or carbocyclic saturated ring; L and K are O or S; M is N or CH; Y is N or CH; Z is hydrogen, alkyl or substituted alkyl; and R1-R4 are as defined in the specification.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: March 23, 2004
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Michele Launay, Dominique Potin, Magali Jeannine Blandine Maillet, Eric Antoine Nicolai, T. G. Murali Dhar, Edwin J. Iwanowicz
  • Spiro-hydantoin compounds useful as anti-inflammatory agents
    Publication number: 20040009998
    Abstract: Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates, enantiomers, and diastereomers, and prodrugs thereof, 1
    Type: Application
    Filed: October 1, 2002
    Publication date: January 15, 2004
    Inventors: T. G. Murali Dhar, Dominique Potin, Magali Jeannine Blandine Maillet, Michele Launay, Eric Antoine Nicolai, Edwin J. Iwanowicz
  • Urazole compounds useful as anti-inflammatory agents
    Patent number: 6673825
    Abstract: Urazole compounds having the formula (I), or pharmaceutically-acceptable salts thereof, are effective as anti-inflammatory or immunosuppressive agents, wherein L and K are O or S; Q is a linker such as —O—, —S—, C(═O), and so forth, R1 is an aryl or heteroaryl group, and R3, R4a, R4c, Z, r, s and t are as defined in the specification.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: January 6, 2004
    Assignees: Bristol-Myers Squibb Co., Cerep SA
    Inventors: Michele Launay, Dominique Potin, Magali Jeannine Blandine Maillet, Eric Antoine Nicolai, Edwin J. Iwanowicz, T. G. Murali Dhar
  • Urazole compounds useful as anti-inflammatory agents
    Publication number: 20030013745
    Abstract: Urazole compounds having the formula (I), 1
    Type: Application
    Filed: May 21, 2002
    Publication date: January 16, 2003
    Inventors: Michele Launay, Dominique Potin, Magali Jeannine Blandine Maillet, Eric Antoine Nicolai, Edwin J. Iwanowicz, T. G. Murali Dhar
  • Hydantoin compounds useful as anti-inflammatory agents
    Publication number: 20020143035
    Abstract: Compounds having the formula (I): 1
    Type: Application
    Filed: November 30, 2001
    Publication date: October 3, 2002
    Inventors: Michele Launay, Dominique Potin, Magali Jeannine Blandine Maillet, Eric Antoine Nicolai, T.G. Murali Dhar, Edwin J. Iwanowicz