Patents by Inventor Mahalakshmi Shankaran

Mahalakshmi Shankaran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for replacing biomarkers of protein kinetics from tissue samples by biomarkers of protein kinetics from body fluids after isotopic labeling in vivo
    Patent number: 9134319
    Abstract: Provided herein are method for measuring the rate of synthesis, breakdown, transport, or other kinetic parameters of a protein in a tissue of medical interest, without requiring physical sampling of the tissue, by a measurement of the protein in a body fluid.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: September 15, 2015
    Assignees: The Regents of the University of California, KineMed, Inc.
    Inventors: Marc K. Hellerstein, Martin Decaris, Mahalakshmi Shankaran
  • Retinoids and Related Compounds for the Treatment of Neuroinflammatory Conditions, Diseases and Disorders
    Publication number: 20080027031
    Abstract: The proliferation and activation of microglia is emerging as an important etiologic factor and target for therapeutic intervention in several CNS diseases, including Alzheimer's disease and multiple sclerosis. Here, we have discovered that retinoic acids dramatically inhibit microglial proliferation in an in vivo model including the widely-used animal model of multiple sclerosis, the experimental autoimmune encephalomyelitis (EAE) mouse model.
    Type: Application
    Filed: March 8, 2007
    Publication date: January 31, 2008
    Applicant: KineMed, Inc.
    Inventors: Marc Hellerstein, Michael Marino, Mahalakshmi Shankaran