Abstract: The present invention addresses the problem of providing a compound for prophylaxis and/or treatment of central inflammatory diseases, or a pharmacologically acceptable salt thereof. The present invention addresses a compound of a general formula (I) or a pharmacologically acceptable salt thereof as a means to solve the problem.

Abstract: The present invention addresses the problem of providing a compound for prophylaxis and/or treatment of central inflammatory diseases, or a pharmacologically acceptable salt thereof. The present invention addresses a compound of a general formula (I) or a pharmacologically acceptable salt thereof as a means to solve the problem. [R1: a C1-C6 alkyl group or the like, R2: a C1-C6 alkyl group or the like, A: a 5-membered aromatic hetero-ring or the like, R3, R3?: a C1-C6 alkyl group or the like.

Abstract: A method of producing a composite nanoparticle (M-AxOy), having: generating, in an inert gas, an alloy (A-M) nanoparticle, which contains 0.1 at. % to 30 at. % of a noble metal (M), with the balance being a base metal (A) and inevitable impurities, and which has a particle size of 1 nm to 100 nm, to heat the alloy (A-M) nanoparticle and to bring the alloy (A-M) nanoparticle into contact with a supplied oxidizing gas during transportation of the alloy (A-M) nanoparticle with the inert gas, to oxidize the base metal component (A) in the floating alloy (A-M) nanoparticle, and to phase separate into the thus-oxidized base metal component (AxOy) and the noble metal component (M), to thereby obtain a composite nanoparticle (M-AxOy) having one noble metal particle (M) combined to the surface of a particulate base metal oxide (AxOy).

Abstract: A method of continuously generating a joined structure: comprising a cube- or quadratic prism-shaped rock salt-type oxide nanoparticle and a metal nanoparticle, and having high crystallinity, in a gas phase, the method is characterized in that alloy nanoparticles composed of a noble metal and a base metal and having a particle size of 1 to 100 nm are generated in an inert gas; and brought into contact with a hot oxidizing gas, while the nanoparticles are heated at a high temperature together with the inert gas, to oxidize a base metal component in the alloy nanoparticles floating in the gas, and to simultaneously allow phase separation of the metal component, whereby the joined structure.

Abstract: A protector (42) of a full-range-air-fuel-ratio sensor (2) is made of a material having an Ni content of 30.0 to 35.0 wt %, a Cr content of 19.0 to 23.0 wt %, an Al content of 0.15 to 0.60 wt %, and containing at least Fe as balance. The material of the protector may further contain Ti in an amount of 0.15 to 0.60 wt %.

Abstract: A method of producing a composite nanoparticle (M-AxOy), having: generating, in an inert gas, an alloy (A-M) nanoparticle, which contains 0.1 at. % to 30 at. % of a noble metal (M), with the balance being a base metal (A) and inevitable impurities, and which has a particle size of 1 nm to 100 nm, to heat the alloy (A-M) nanoparticle and to bring the alloy (A-M) nanoparticle into contact with a supplied oxidizing gas during transportation of the alloy (A-M) nanoparticle with the inert gas, to oxidize the base metal component (A) in the floating alloy (A-M) nanoparticle, and to phase separate into the thus-oxidized base metal component (AxOy) and the noble metal component (M), to thereby obtain a composite nanoparticle (M-AxOy) having one noble metal particle (M) combined to the surface of a particulate base metal oxide (AxOy).

Abstract: A gas sensor including: a gas detection element; a metal shell extending in an axial direction; and a metal cylinder extending in an axial direction, wherein a leading end portion of the metal cylinder surrounds a base end portion of the metal shell and is fixed to the metal shell via a circumferential welded portion. The metal shell includes: Fe in an amount equal to or more than 50.0 mass %; C in an amount of 0.02 mass % to 0.15 mass %; Cr in an amount of 11.5 mass % to 18.0 mass %; and Nb in an amount equal to or more than twice amount of C in mass %.

Abstract: A neutralization apparatus comprising an ion generation element employing a novel, high efficiency discharge system capable of generating high concentration ions with a low ozone concentration. In the neutralization apparatus, the ion generation element is a minute electrode ion generation element consisting of a discharge electrode and an induction electrode having minute protrusions arranged in one direction on a plane, and a thin dielectric film sandwiched between them.

Abstract: A gas sensor extending along an axial direction, the gas sensor including: a housing having a through hole, the through hole including an expanding portion at a leading end thereof; a gas sensing element inserted into the housing, having a closed leading end, and provided with a sensor electrode on an outer surface of the leading end side thereof; a heater inserted into the gas sensor, and including a contact portion where the heater contacts an inner surface; an protector fixed on the leading end side of the housing and having an outer protector including an outer air hole and an inner protector being positioned within the outer protector and spaced apart from the outer protector in the radial direction; and an inner air vent provided between the inner protector and the leading end of the housing.

Abstract: An ion generating element capable of cost reduction and space saving while exhibiting a high generation efficiency of positive ions and negative ions and stabilized generation capacity with less variation, and an ion generator and a neutralizer employing it. The ion generating element comprises a dielectric body having at least two faces, at least two discharge electrodes arranged on the at least two faces of the dielectric body, and an induction electrode arranged in the dielectric body and subjected to the action of the at least two discharge electrodes and is characterized in that positive ions and negative ions are generated on the body, and ions are generated from the at least two faces of the dielectric body through discharge generated because of the potential difference between the discharge electrode of the ion generating element and the induction electrode when a drive voltage is applied between them.

Abstract: The present invention is relating to an ion generator and an ionizer, in which the ion generator can obtain stable ion generation even if the electrode and the power supply slightly change, satisfies voltage and frequency conditions for realizing an ozone concentration less than 50 ppb as an allowable concentration.

Abstract: A gas sensor including: a gas detection element; a metal shell extending in an axial direction; and a metal cylinder extending in an axial direction, wherein a leading end portion of the metal cylinder surrounds a base end portion of the metal shell and is fixed to the metal shell via a circumferential welded portion. The metal shell includes: Fe in an amount equal to or more than 50.0 mass %; C in an amount of 0.02 mass % to 0.15 mass %; Cr in an amount of 11.5 mass % to 18.0 mass %; and Nb in an amount equal to or more than twice amount of C in mass %.

Abstract: An ion generating element capable of cost reduction and space saving while exhibiting a high generation efficiency of positive ions and negative ions and stabilized generation capacity with less variation, and an ion generator and a neutralizer employing it. The ion generating element comprises a dielectric body having at least two faces, at least two discharge electrodes arranged on the at least two faces of the dielectric body, and an induction electrode arranged in the dielectric body and subjected to the action of the at least two discharge electrodes and is characterized in that positive ions and negative ions are generated on the body, and ions are generated from the at least two faces of the dielectric body through discharge generated because of the potential difference between the discharge electrode of the ion generating element and the induction electrode when a drive voltage is applied between them.

Abstract: An oil agent of the kind and amount suitable for a post-step is applied on a workpiece regardless of the kind and residual amount of an oil agent used in a pre-step. A workpiece on which a first oil agent is deposited is immersed in a degreasing solution, taken out of the degreasing solution and cleaned to thereby remove all the first oil agent. Then, the workpiece having all the first oil agent removed is immersed in an oil agent solution to thereby newly deposit a second oil agent of the kind and amount suitable for a post-step on the workpiece.

Abstract: An oxygen sensor 10 includes an oxygen detection element 20, which assumes a hollow tubular shape extending along the axis. The oxygen detection element 20 has a closed tip end and an opened rear end. An internal electrode layer 23 is formed on an inner circumferential surface 22 of the oxygen detection element 20. The sensor 10 also has a terminal member 30 which is in contact with the internal electrode layer 23 and in electrical connection therewith. The terminal member 30 has press contact portions 34c and 34d which come into press contact with the inner circumferential surface 22 of the oxygen detection element 20 to hold the terminal member 30 in the oxygen detection element 20, and conduction portions 35b which come into press contact with the internal electrode layer 23 on the inner circumferential surface 22 of the oxygen detection element 20 and into electrical connection with the internal electrode layer 23.

Abstract: A neutralization apparatus comprising an ion generation element employing a novel, high efficiency discharge system capable of generating high concentration ions with a low ozone concentration. In the neutralization apparatus, the ion generation element is a minute electrode ion generation element consisting of a discharge electrode and an induction electrode having minute protrusions arranged in one direction on a plane, and a thin dielectric film sandwiched between them.

Abstract: The present invention is relating to an ion generator and an ionizer, in which the ion generator can obtain stable ion generation even if the electrode and the power supply slightly change, satisfies voltage and frequency conditions for realizing an ozone concentration less than 50 ppb as an allowable concentration.

Abstract: An oil agent of the kind and amount suitable for a post-step is applied on a workpiece regardless of the kind and residual amount of an oil agent used in a pre-step. A workpiece on which a first oil agent is deposited is immersed in a degreasing solution, taken out of the degreasing solution and cleaned to thereby remove all the first oil agent. Then, the workpiece having all the first oil agent removed is immersed in an oil agent solution to thereby newly deposit a second oil agent of the kind and amount suitable for a post-step on the workpiece.

Abstract: An oxygen sensor 10 includes an oxygen detection element 20, which assumes a hollow tubular shape extending along the axis. The oxygen detection element 20 has a closed tip end and an opened rear end. An internal electrode layer 23 is formed on an inner circumferential surface 22 of the oxygen detection element 20. The sensor 10 also has a terminal member 30 which is in contact with the internal electrode layer 23 and in electrical connection therewith. The terminal member 30 has press contact portions 34c and 34d which come into press contact with the inner circumferential surface 22 of the oxygen detection element 20 to hold the terminal member 30 in the oxygen detection element 20, and conduction portions 35b which come into press contact with the internal electrode layer 23 on the inner circumferential surface 22 of the oxygen detection element 20 and into electrical connection with the internal electrode layer 23.

Abstract: A method and an apparatus for separating fine particles of different fine particle sizes, structures, and functions are provided. The method includes the steps of introducing a group of fine particles of different sizes, structures, and functions into an atmosphere of an adsorption fluid; effecting critical adsorption of the adsorption molecular species to specific sites of the fine particles and, subsequently, separating the fine particles according to size, structure, or function based on one of the masses, the particle diameters, the fluid resistances, and the functions of adsorption abilities to a third substance, which have been changed due to the critical adsorption, or at least two of them in combination.