Patents by Inventor Manabu ARAKI

Manabu ARAKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240043526
    Abstract: It has become clear that the therapeutic effect of an IL-6 inhibitor for IL-6- and neutrophil-associated diseases can be predicted using the expression level of neutrophil-associated genes as an indicator. It has also become clear that an IL-6 inhibitor is effective for the treatment of IL-6- and neutrophil-associated diseases in patients with high expression levels of neutrophil-associated genes. The present invention provides a method for selecting cases of IL-6- and neutrophil-associated diseases in which treatment with an IL-6 inhibitor is effective, as well as a method for effectively treating patients with IL-6- and neutrophil-associated diseases and with high expression levels of neutrophil-associated genes.
    Type: Application
    Filed: June 23, 2023
    Publication date: February 8, 2024
    Inventors: Takako MATSUOKA, Manabu ARAKI, Takashi YAMAMURA
  • Patent number: 11851486
    Abstract: It has become clear that the therapeutic effect of an IL-6 inhibitor for IL-6- and neutrophil-associated diseases can be predicted using the expression level of neutrophil-associated genes as an indicator. It has also become clear that an IL-6 inhibitor is effective for the treatment of IL-6- and neutrophil-associated diseases in patients with high expression levels of neutrophil-associated genes. The present invention provides a method for selecting cases of IL-6- and neutrophil-associated diseases in which treatment with an IL-6 inhibitor is effective, as well as a method for effectively treating patients with IL-6- and neutrophil-associated diseases and with high expression levels of neutrophil-associated genes.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: December 26, 2023
    Assignees: National Center of Neurology and Psychiatry, Chugai Seiyaku Kabushiki Kaisha
    Inventors: Takako Matsuoka, Manabu Araki, Takashi Yamamura
  • Patent number: 11794988
    Abstract: To avoid or reduce the necessity of loading a cargo container on a container carrying vehicle, for example, a cargo container 100 includes: engaging portions 101b disposed at four corners of each of upper and lower surfaces of a shell 101 and each engageable with a spreader of a container crane; and a wheel 113 capable of supporting the cargo container 100 such that the cargo container 100 is allowed to run. The wheel 113 is switchable between a runnable state where at least a lowermost portion is located below a bottom surface 101c of the cargo container 100 and supports the cargo container 100 such that the cargo container 100 is allowed to run, and a loaded state where the wheel 113 moves inward from the bottom surface 101c and the bottom surface 101c is allowed to make contact with a mount surface of the cargo container 100.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: October 24, 2023
    Assignee: SHIBAKAI CO., LTD.
    Inventors: Manabu Araki, Toru Araki
  • Patent number: 11401118
    Abstract: A method of handling bulk cargo, including suspending, with a spreader of a container crane, a cargo handling system above a dock where a ship loaded with bulk cargo lands, the cargo handling system including a frame having an engaging portion engageable with the spreader of the container crane, a blower attached to the frame and configured to suck air, and a separator attached to the frame and configured to separate bulk cargo sucked along with the air from the air sucked by the blower. While the cargo handling system is suspended above the dock, using the cargo handling system to suck up the bulk cargo from the ship with the blower of the cargo handling system together with the air; separate the bulk cargo from the air with the separator of the cargo handling system; and discharge the separated bulk cargo from the cargo handling system.
    Type: Grant
    Filed: February 24, 2021
    Date of Patent: August 2, 2022
    Assignee: SHIBAKAI CO., LTD.
    Inventors: Manabu Araki, Toru Araki
  • Patent number: 11142411
    Abstract: The availability of a container crane or a dock is improved. A cargo handling method includes steps of: moving a lighter 601 to a different dock, the lighter 601 carrying a freight container wheeled platform 501 loaded on the lighter 601, the freight container wheeled platform 501 carrying a container 401 placed on the freight container wheeled platform 501 in a container yard; and unloading the freight container wheeled platform 501 from the lighter 601 to the different dock.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: October 12, 2021
    Assignee: SHIBAKAI CO., LTD.
    Inventors: Manabu Araki, Toru Araki
  • Publication number: 20210206566
    Abstract: To avoid or reduce the necessity of loading a cargo container on a container carrying vehicle, for example, a cargo container 100 includes: engaging portions 101b disposed at four corners of each of upper and lower surfaces of a shell 101 and each engageable with a spreader of a container crane; and a wheel 113 capable of supporting the cargo container 100 such that the cargo container 100 is allowed to run. The wheel 113 is switchable between a runnable state where at least a lowermost portion is located below a bottom surface 101c of the cargo container 100 and supports the cargo container 100 such that the cargo container 100 is allowed to run, and a loaded state where the wheel 113 moves inward from the bottom surface 101c and the bottom surface 101c is allowed to make contact with a mount surface of the cargo container 100.
    Type: Application
    Filed: May 29, 2018
    Publication date: July 8, 2021
    Inventors: Manabu ARAKI, Toru ARAKI
  • Publication number: 20210179367
    Abstract: A method of handling bulk cargo, including suspending, with a spreader of a container crane, a cargo handling system above a dock where a ship loaded with bulk cargo lands, the cargo handling system including a frame having an engaging portion engageable with the spreader of the container crane, a blower attached to the frame and configured to suck air, and a separator attached to the frame and configured to separate bulk cargo sucked along with the air from the air sucked by the blower. While the cargo handling system is suspended above the dock, using the cargo handling system to suck up the bulk cargo from the ship with the blower of the cargo handling system together with the air; separate the bulk cargo from the air with the separator of the cargo handling system; and discharge the separated bulk cargo from the cargo handling system.
    Type: Application
    Filed: February 24, 2021
    Publication date: June 17, 2021
    Inventors: Manabu ARAKI, Toru ARAKI
  • Publication number: 20200148760
    Abstract: It has become clear that the therapeutic effect of an IL-6 inhibitor for IL-6- and neutrophil-associated diseases can be predicted using the expression level of neutrophil-associated genes as an indicator. It has also become clear that an IL-6 inhibitor is effective for the treatment of IL-6- and neutrophil-associated diseases in patients with high expression levels of neutrophil-associated genes. The present invention provides a method for selecting cases of IL-6- and neutrophil-associated diseases in which treatment with an IL-6 inhibitor is effective, as well as a method for effectively treating patients with IL-6- and neutrophil-associated diseases and with high expression levels of neutrophil-associated genes.
    Type: Application
    Filed: May 1, 2018
    Publication date: May 14, 2020
    Inventors: Takako MATSUOKA, Manabu ARAKI, Takashi YAMAMURA
  • Patent number: 10407137
    Abstract: To be able to improve the flexibility in handling containers, a container ship configured to transport containers includes: an opening 106 through which cargo may be handled by moving a wheeled platform 501 between the container ship and a dock, the wheeled platform 501 including a plurality of containers 401 placed thereon; and a floor board 108 or a rail configured to support the wheeled platform 501 loaded from the dock through the opening 106.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: September 10, 2019
    Assignee: SHIBAKAI CO., LTD.
    Inventors: Manabu Araki, Toru Araki
  • Publication number: 20180354588
    Abstract: To be able to improve the flexibility in handling containers, a container ship configured to transport containers includes: an opening 106 through which cargo may be handled by moving a wheeled platform 501 between the container ship and a dock, the wheeled platform 501 including a plurality of containers 401 placed thereon; and a floor board 108 or a rail configured to support the wheeled platform 501 loaded from the dock through the opening 106.
    Type: Application
    Filed: September 12, 2016
    Publication date: December 13, 2018
    Inventors: Manabu ARAKI, Toru ARAKI
  • Publication number: 20180050875
    Abstract: The availability of a container crane or a dock is improved. A cargo handling method includes steps of: moving a lighter 601 to a different dock, the lighter 601 carrying a freight container wheeled platform 501 loaded on the lighter 601, the freight container wheeled platform 501 carrying a container 401 placed on the freight container wheeled platform 501 in a container yard; and unloading the freight container wheeled platform 501 from the lighter 601 to the different dock.
    Type: Application
    Filed: March 4, 2015
    Publication date: February 22, 2018
    Inventors: Manabu ARAKI, Toru ARAKI
  • Publication number: 20180037406
    Abstract: The flexibility in landing bulk cargo is improved, and a dock is effectively used. A freight container includes an outer shell configured to contain bulk cargo. The outer shell includes an engageable portion 402 engageable with a spreader of a container crane, an opening 403 through which bulk cargo flows into the outer shell, and a filter 404 configured to exhaust air in the outer shell.
    Type: Application
    Filed: March 4, 2015
    Publication date: February 8, 2018
    Inventors: Manabu ARAKI, Toru ARAKI
  • Publication number: 20180037422
    Abstract: The flexibility in landing bulk cargo is improved, and a dock is effectively used. A cargo handling system configured to suck, transport, and handle bulk cargo includes a frame 202 having an engaging portion engageable with a spreader of a container crane, a blower 233 attached to the frame, and configured to suck air, and a separator 231 attached to the frame, and configured to separate bulk cargo sucked along with the air from the air sucked by the blower.
    Type: Application
    Filed: March 4, 2015
    Publication date: February 8, 2018
    Inventors: Manabu ARAKI, Toru ARAKI