Publication number: 20220340566
Abstract: A compound represented by formula (I): or its pharmaceutically acceptable salt, wherein a group represented by formula: is a group represented by formula: R1 is each independently halogen, hydroxy, cyano or the like; m is 0, 1, 2, 3 or 4; R2 is a hydrogen atom, halogen, cyano, substituted or unsubstituted alkyl or the like; R3a, R3b, R3c and R3d are each independently hydrogen atom, halogen or the like, with the proviso that R3a, R3b, R3c and R3d are not simultaneously hydrogen atom; ring C is represented as follows: X is CH or N; Y is CH or N; R4 is each independently halogen, hydroxy, cyano or the like; p is 0 or 1; q is 0, 1, 2, 3 or 4; R5 is CR5C or N; R6 is CR6C or N; R7 is CR7C or N; R8 is CR8C or N; R9 is CR9C or N; with the proviso that R5, R6, R7, R8 and R9 are not simultaneously N; R5C, R6C, R7C, R8C and R9C are each independently hydrogen atom or the like.
Type:
Application
Filed:
September 10, 2020
Publication date:
October 27, 2022
Applicants:
Shionogi & Co., Ltd., HSIRI THERAPEUTICS, INC.
Inventors:
Manabu FUJITANI, Tsutomu IWAKI, Rina NAKAMURA, Marvin J. MILLER, Garrett C. MORASKI
