Patents by Inventor Marek Kwiatkowski

Marek Kwiatkowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180360974
    Abstract: The present application provides compounds of Formula (B): or pharmaceutically acceptable salts thereof, wherein D is a residue of a biologically active drug, which underdo hydrolysis under physiological conditions to release the biologically active drug and which are useful in the treatment of disorders that could be beneficially treated with the drug.
    Type: Application
    Filed: March 12, 2018
    Publication date: December 20, 2018
    Inventors: Marek Kwiatkowski, Christian Sund
  • Patent number: 10125220
    Abstract: This document relates to functionalized (e.g., mono- or bi-functional) polymers (e.g., polyethylene glycol and related polymers) as well as methods and materials for making and using such functionalized polymers.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: November 13, 2018
    Assignee: QuiaPEG Pharmaceuticals AB
    Inventor: Marek Kwiatkowski
  • Publication number: 20180251598
    Abstract: This document relates to functionalized (e.g., mono- or bi-functional) polymers (e.g., polyethylene glycol and related polymers) as well as methods and materials for making and using such functionalized polymers.
    Type: Application
    Filed: October 9, 2017
    Publication date: September 6, 2018
    Inventor: Marek Kwiatkowski
  • Patent number: 10010621
    Abstract: This document relates to conjugates of a biologically active molecule or a derivative thereof and functionalized (e.g., mono- or bi-functional) polymers (e.g., polyethylene glycol and related polymers) as well as methods and materials for making and using such conjugates.
    Type: Grant
    Filed: June 12, 2013
    Date of Patent: July 3, 2018
    Assignee: QuiaPEG Pharmaceuticals AB
    Inventor: Marek Kwiatkowski
  • Patent number: 9849187
    Abstract: This document relates to conjugates of TNF inhibitors or derivatives thereof and functionalized (e.g., mono- or bi-functional) polymers (e.g., polyethylene glycol and related polymers) as well as methods and materials for making and using such conjugates.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: December 26, 2017
    Assignee: QuiaPEG Pharmaceuticals AB
    Inventor: Marek Kwiatkowski
  • Patent number: 9790324
    Abstract: This document relates to functionalized (e.g., mono- or bi-functional) polymers (e.g., polyethylene glycol and related polymers) as well as methods and materials for making and using such functionalized polymers.
    Type: Grant
    Filed: September 29, 2014
    Date of Patent: October 17, 2017
    Inventor: Marek Kwiatkowski
  • Publication number: 20160354477
    Abstract: This document relates to conjugates of TNF inhibitors or derivatives thereof and functionalized (e.g., mono- or bi-functional) polymers (e.g., polyethylene glycol and related polymers) as well as methods and materials for making and using such conjugates.
    Type: Application
    Filed: December 28, 2015
    Publication date: December 8, 2016
    Inventor: Marek Kwiatkowski
  • Patent number: 9220789
    Abstract: This document relates to conjugates of TNF inhibitors or derivatives thereof and functionalized (e.g., mono- or bi-functional) polymers (e.g., polyethylene glycol and related polymers) as well as methods and materials for making and using such conjugates.
    Type: Grant
    Filed: June 12, 2013
    Date of Patent: December 29, 2015
    Assignee: QuiaPEG Pharmaceuticals AB
    Inventor: Marek Kwiatkowski
  • Publication number: 20150232615
    Abstract: This document relates to functionalized (e.g., mono- or bi-functional) polymers (e.g., polyethylene glycol and related polymers) as well as methods and materials for making and using such functionalized polymers.
    Type: Application
    Filed: September 29, 2014
    Publication date: August 20, 2015
    Inventor: Marek Kwiatkowski
  • Publication number: 20150147345
    Abstract: This document relates to conjugates of a biologically active molecule or a derivative thereof and functionalized (e.g., mono- or bi-functional) polymers (e.g., polyethylene glycol and related polymers) as well as methods and materials for making and using such conjugates.
    Type: Application
    Filed: June 12, 2013
    Publication date: May 28, 2015
    Inventor: Marek Kwiatkowski
  • Patent number: 8846941
    Abstract: This document relates to functionalized (e.g., mono- or bi-functional) polymers (e.g., polyethylene glycol and related polymers) as well as methods and materials for making and using such functionalized polymers.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: September 30, 2014
    Assignee: QuiaPEG AB
    Inventor: Marek Kwiatkowski
  • Publication number: 20140030278
    Abstract: This document relates to conjugates of TNF inhibitors or derivatives thereof and functionalized (e.g., mono- or bi-functional) polymers (e.g., polyethylene glycol and related polymers) as well as methods and materials for making and using such conjugates.
    Type: Application
    Filed: June 12, 2013
    Publication date: January 30, 2014
    Inventor: Marek Kwiatkowski
  • Publication number: 20120178940
    Abstract: This document relates to functionalized (e.g., mono- or bi-functional) polymers (e.g., polyethylene glycol and related polymers) as well as methods and materials for making and using such functionalized polymers.
    Type: Application
    Filed: December 13, 2011
    Publication date: July 12, 2012
    Inventor: Marek Kwiatkowski
  • Publication number: 20080281903
    Abstract: A system for providing interactive multimedia content includes an electronic device having a unique identification and an personalized content profile associated therewith. The electronic device includes an input device that receives data input by the user, a transmitter that transmits data, including data input by the user, to a provider system, a receiver that receives encoded multimedia content from the provider system and an output device that provides decoded multimedia content to a user. The electronic device further includes one or more controllers that control the operation of the input device, the transmitter, the receiver and the output device. The controllers decode the encoded multimedia content and output the decoded multimedia content through the output device. The decoding and output is based, at least in part, on the device's personalized content profile.
    Type: Application
    Filed: May 10, 2007
    Publication date: November 13, 2008
    Inventor: Marek Kwiatkowski
  • Patent number: 7345163
    Abstract: Methods for deprotecting and derivatizing oligonucleotides that are non-covalently bound to a solid support are described. The methods include providing a plurality of oligonucleotides linked to one or more hydrophobic separation functions, wherein the plurality includes protected oligonucleotides, precipitating the plurality of oligonucleotides on a hydrophobic solid support using an organic solvent to produce non-covalently immobilized oligonucleotides, and deprotecting the immobilized oligonucleotides.
    Type: Grant
    Filed: August 28, 2002
    Date of Patent: March 18, 2008
    Assignee: Quiatech AB
    Inventor: Marek Kwiatkowski
  • Patent number: 7279563
    Abstract: A hydrocarbyldithiomethyl-modified compound of the Formula: R1—O—CH2—S—S—R2 or a salt thereof wherein R1 is an organic molecule and R2 is a hydrocarbyl is useful for protecting and/or blocking hydroxyl groups in organic molecules such as nucleotides. The hydrocarbyldithiomethyl-modified compounds can also be used for chemically synthesizing oligonucleotides and for sequencing nucleic acid compounds.
    Type: Grant
    Filed: October 27, 2003
    Date of Patent: October 9, 2007
    Assignee: Helicos BioSciences Corporation
    Inventor: Marek Kwiatkowski
  • Patent number: 7118864
    Abstract: Synthetic probes and methods for detecting analytes using such probes are described. The probes contain an analyte reactive moiety linked to a nucleic acid molecule that can be extended by DNA polymerase.
    Type: Grant
    Filed: May 9, 2002
    Date of Patent: October 10, 2006
    Assignee: Quiatech AB
    Inventor: Marek Kwiatkowski
  • Publication number: 20050027116
    Abstract: The present invention relates to a support system for solid phase synthesis of oligomers, such as oligonucleotides, wherein the starting compound is bound to the support via a disiloxyl linkage. Furthermore, the invention relates to a method for synthesis of oligonucleotides on a solid support. The support system comprises a stable disiloxyl linkage providing high nucleoside loadings to the support and the method allows convenient non-laborious oligomer synthesis.
    Type: Application
    Filed: October 14, 2003
    Publication date: February 3, 2005
    Inventors: Marek Kwiatkowski, Mats Nilsson, Ulf Landegren
  • Patent number: 6790946
    Abstract: A method of preparing an immobilized oligonucleotide having a free 3′-end comprises the steps of: i) preparing an oligonucleotide attached in a first position to a solid support via its 3′-end and having a free 5′-end; ii) binding said oligonucleotide in a second position remote from the 3′-end to the solid support; and iii) selectively releasing the 3′-end of the oligonucleotide from the solid support to obta the oligonucleotide attached to the support in said second position in a reversed orientation with a free 3′-end.
    Type: Grant
    Filed: September 12, 2001
    Date of Patent: September 14, 2004
    Assignee: Quiatech AB
    Inventors: Marek Kwiatkowski, Ulf Landegren, Mats Nilsson
  • Publication number: 20040175726
    Abstract: A hydrocarbyldithiomethyl-modified compound of the Formula:
    Type: Application
    Filed: October 27, 2003
    Publication date: September 9, 2004
    Applicant: Quiatech AB, a Swedish corporation
    Inventor: Marek Kwiatkowski