Patents by Inventor Margaret H. Sherlock

Margaret H. Sherlock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Naphthyridines which affect IL-4 and G-CSF
    Patent number: 5939431
    Abstract: Compounds of formula ##STR1## or pharmaceutically acceptable salts thereof, wherein E, Q, T, U, V, L, Z, X, W, M, Y and Y' are as set forth herein, are described. These compounds are useful as agents in the treatment of allergy, inflammation, autoimmune diseases, B-cell lymphomas, tumors, and the after effects of bone marrow transplantation.
    Type: Grant
    Filed: June 19, 1997
    Date of Patent: August 17, 1999
    Assignee: Schering Corporation
    Inventors: Daniel M. Solomon, Michael J. Grace, Jay S. Fine, Loretta A. Bober, Margaret H. Sherlock
  • Heterobicyclic compounds having antiinflammatory activity
    Patent number: 5182289
    Abstract: Heterobicyclic and heterocyclic intermediate compounds and their use in treating inflammation, hyperproliferative skin conditions such as psoriasis and allergy are disclosed.
    Type: Grant
    Filed: December 10, 1990
    Date of Patent: January 26, 1993
    Assignee: Schering Corporation
    Inventors: Pauline C. Ting, Margaret H. Sherlock, Wing C. Tom, James J. Kaminski
  • Method for treating allergic reactions and compositions therefore
    Patent number: 4628055
    Abstract: Certain substituted 1,8-naphthyridines and 1,5,8-azanaphthyridines are useful for treating allergic reactions in mammals. Certain of the compounds may also be utilized to treat chronic obstructive lung diseases in mammals.Methods for preparing the compounds and methods for their use are also described.
    Type: Grant
    Filed: October 15, 1984
    Date of Patent: December 9, 1986
    Assignee: Schering Corporation
    Inventor: Margaret H. Sherlock
  • Substituted 1,8-naphthyridinones, useful as anti-allergic agents
    Patent number: 4596809
    Abstract: Substituted 1,8-naphthyridinones are anti-allergic, anti-inflammatory and cytoprotective agents. Methods for their preparation and use are disclosed.
    Type: Grant
    Filed: March 25, 1985
    Date of Patent: June 24, 1986
    Assignee: Schering Corporation
    Inventor: Margaret H. Sherlock
  • Anti-inflammatory 1-mercaptoalkyl-substituted-2-imidazolidinone derivatives, composition, and method of use therefor
    Patent number: 4579857
    Abstract: 1-Mercaptoalkyl-substituted-2-imidazolidinones having anti-inflammatory activity are disclosed. Methods for their preparation and use are described.
    Type: Grant
    Filed: February 14, 1983
    Date of Patent: April 1, 1986
    Assignee: Schering Corporation
    Inventor: Margaret H. Sherlock
  • Composition containing 1-phenyl-1,8-naphthridin-2(1H)-ones and a non-steroidal anti-inflammatory drug
    Patent number: 4551463
    Abstract: Certain substitute 1,8-naphthyridines and 1,5,8-azanaphthyridines are useful in treating and preventing ulcers in mammals.Methods for preparing the compounds and methods for their use are also described.
    Type: Grant
    Filed: September 19, 1983
    Date of Patent: November 5, 1985
    Assignee: Schering Corporation
    Inventor: Margaret H. Sherlock
  • 1-Phenyl-1,8-naphthridin-2(1H)-ones
    Patent number: 4492702
    Abstract: Certain substituted 1,8-naphthyridines and 1,5,8-azanaphthyridines are useful for treating allergic reactions in mammals. Certain of the compounds may also be utilized to treat chronic obstructive lung diseases in mammals.Methods for preparing the compounds and methods for their use are also described.
    Type: Grant
    Filed: September 19, 1983
    Date of Patent: January 8, 1985
    Assignee: Schering Corporation
    Inventor: Margaret H. Sherlock
  • Salts of 3(n-butyl)-4-hydroxy-1-phenyl-1,8-naphthyridine-2(1H)-one and their use in treating chronic obstructive lung diseases
    Patent number: 4452800
    Abstract: There are disclosed certain alkali metal, alkaline earth metal, amine and amino acid salts of 3-(n-butyl)-4-hydroxy-1-phenyl-1,8-naphthyridine-2(1H)-one which, unlike the parent compound, are useful for orally treating chronic obstructive lung diseases such as asthma, bronchitis and the like.
    Type: Grant
    Filed: April 26, 1982
    Date of Patent: June 5, 1984
    Assignee: Schering Corporation
    Inventor: Margaret H. Sherlock
  • Process for preparing 1-aminonaphthyridines
    Patent number: 4260759
    Abstract: This invention relates to 1-amino naphthyridines prepared by a base-catalyzed condensation while in an aprotic solvent. In this condensation an o-alkyl aryl nitrile may be reacted either with the same or different o-alkyl aryl nitrile or with another nitrile. The 1-amino naphthyridines are useful as antifungal and antibacterial agents.
    Type: Grant
    Filed: August 14, 1978
    Date of Patent: April 7, 1981
    Assignee: Schering-Corporation
    Inventors: Joseph Mayer, Margaret H. Sherlock
  • Anti-diarrheal anilino nicotinic acids and method of using same
    Patent number: 4205073
    Abstract: This invention relates to compositions of matter useful as anti-diarrheal agents and to the method of controlling and treating diarrhea in warm blooded animals. The active anti-diarrheal agents are substituted anilino nicotinic acids, and salts thereof and ester and hydrazine derivatives of said acids.
    Type: Grant
    Filed: April 30, 1975
    Date of Patent: May 27, 1980
    Assignee: Schering Corporation
    Inventors: Margaret H. Sherlock, James F. Long
  • 5-(Substituted triphenylmethyl)picolinamides and their use as anti-acne agents
    Patent number: 4139625
    Abstract: Disclosed herein are novel 5-tritylpicolinic acids, amides, esters and pharmaceutically acceptable salts thereof. Also disclosed are methods for the use of said novel compounds as anti-acne agents.
    Type: Grant
    Filed: August 12, 1977
    Date of Patent: February 13, 1979
    Assignee: Schering Corporation
    Inventor: Margaret H. Sherlock
  • Diphenylmethyl picolinic acid derivatives and their use as anti-acne agents
    Patent number: 4138488
    Abstract: Disclosed herein are substituted diphenylmethyl picolinic acids, pharmaceutically acceptable salts, amides and esters thereof. The compounds disclosed are useful as topical anti-acne agents.
    Type: Grant
    Filed: January 10, 1977
    Date of Patent: February 6, 1979
    Assignee: Schering Corporation
    Inventors: Margaret H. Sherlock, Heide Roebke
  • Trityl picolinic acid derivatives and their use as anti-acne agents
    Patent number: 4133887
    Abstract: Disclosed herein are novel 5-tritylpicolinic acids, amides, esters and pharmaceutically acceptable salts thereof. Also disclosed are methods for the use of said novel compounds as anti-acne agents.
    Type: Grant
    Filed: August 12, 1977
    Date of Patent: January 9, 1979
    Assignee: Schering Corporation
    Inventor: Margaret H. Sherlock
  • Cyanoalkyl-5-(substituted triphenylmethyl)picolinate
    Patent number: 4127662
    Abstract: Disclosed herein are novel 5-tritylpicolinic acids, amides, esters and pharmaceutically acceptable salts thereof. Also disclosed are methods for the use of said novel compounds as anti-acne agents.
    Type: Grant
    Filed: August 12, 1977
    Date of Patent: November 28, 1978
    Assignee: Schering Corporation
    Inventor: Margaret H. Sherlock
  • N-1-(p-Biphenylalkyl)piperazines and their use as anti-inflammatory agents
    Patent number: 4125612
    Abstract: This invention relates to N-1(p-biphenylalkyl) piperazines, to the processes for making such compounds and to the use of such compounds as anti-inflammatory agents, particularly useful in the treatment of rheumatoid arthritis.
    Type: Grant
    Filed: June 20, 1977
    Date of Patent: November 14, 1978
    Assignee: Schering Corporation
    Inventor: Margaret H. Sherlock
  • 2-Cyano-5-(substituted triphenylmethyl) pyridines
    Patent number: 4123433
    Abstract: Disclosed herein are novel 5-tritylpicolinic acids, amides, esters and pharmaceutically acceptable salts thereof. Also disclosed are methods for the use of said novel compounds as anti-acne agents.
    Type: Grant
    Filed: August 12, 1977
    Date of Patent: October 31, 1978
    Assignee: Schering Corporation
    Inventor: Margaret H. Sherlock
  • 1-Aminonaphthyridines
    Patent number: 4115395
    Abstract: This invention relates to 1-amino naphthyridines prepared by a base-catalyzed condensation while in an aprotic solvent. In this condensation an o-alkyl aryl nitrile may be reacted either with the same or different o-alkyl aryl nitrile or with another nitrile. The 1-amino naphthyridines are useful as antifungal and antibacterial agents.
    Type: Grant
    Filed: January 26, 1977
    Date of Patent: September 19, 1978
    Assignee: Schering Corporation
    Inventors: Joseph Mayer, Margaret H. Sherlock
  • Certain amino naphthyridines
    Patent number: 4107166
    Abstract: This invention relates to 1-amino naphthyridines prepared by a base-catalyzed condensation while in an aprotic solvent. In this condensation an o-alkyl aryl nitrile may be reacted either with the same or different o-alkyl aryl nitrile or with another nitrile. The 1-amino naphthyridines are useful as antifungal and antibacterial agents.
    Type: Grant
    Filed: April 11, 1977
    Date of Patent: August 15, 1978
    Assignee: Schering Corporation
    Inventors: Joseph Mayer, Margaret H. Sherlock
  • Trityl picolinic acid derivatives and their use as anti-acne agents
    Patent number: 4044140
    Abstract: Disclosed herein are novel 5-tritylpicolinic acids, amides, esters and pharmaceutically acceptable salts thereof. Also disclosed are methods for the use of said novel compounds as anti-acne agents.
    Type: Grant
    Filed: November 28, 1975
    Date of Patent: August 23, 1977
    Assignee: Schering Corporation
    Inventor: Margaret H. Sherlock
  • Anti-diarrheal anthranilic acids
    Patent number: 4029815
    Abstract: This invention relates to compositions of matter useful as anti-diarrheal agents and to the method of controlling and treating diarrhea in warm blooded animals. The active anti-diarrheal agents are substituted N-aryl-anthranilic acids, and salts thereof and ester and hydrazine derivatives of said acids.
    Type: Grant
    Filed: April 30, 1975
    Date of Patent: June 14, 1977
    Assignee: Schering Corporation
    Inventors: Margaret H. Sherlock, James F. Long