Patents by Inventor Margaret M. Billingsley

Margaret M. Billingsley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AMNIOTIC FLUID STABILIZED COMPOSITIONS AND METHODS FOR IN UTERO DELIVERY OF THERAPEUTIC AGENTS
    Publication number: 20240325308
    Abstract: The present disclosure relates, in part, to lipid nanoparticles (LNPs), and compositions comprising the same, which have increased stability in amniotic fluid, and methods of use thereof for in utero delivery of therapeutic agents, to treat and/or prevent diseases and/or disorders in a fetal subject. The present disclosure further relates to an ex vivo assay for screening LNP stability in a test fluid.
    Type: Application
    Filed: August 3, 2022
    Publication date: October 3, 2024
    Applicants: The Trustees of the University of Pennsylvania, The Children's Hospital of Philadelphia
    Inventors: Michael Mitchell, Kelsey L. Swingle, Margaret M. Billingsley, William Peranteau