Patents by Inventor Maria Drangova
Maria Drangova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11844627Abstract: A device including a base sized to be hand-held, the base defining a longitudinal axis between first and second opposing longitudinal ends, a cover reversibly fastened to the base in a closed position; a sheath clamp coupled to the base, the sheath clamp capturing a sheath handle of a sheath to immobilize the sheath handle relative to the base, wherein the sheath clamp is an aperture formed in corresponding abutting edges of the cover and the base, the aperture being formed when the cover and the base are in the closed position; a catheter clamp capturing a catheter, a remote end of the catheter configured to deliver a catheterized medical procedure; the catheter clamp aligned to be substantially co-axial with the sheath clamp; and a linear actuator effecting back-and-forth linear motion of the catheter clamp relative to the sheath clamp.Type: GrantFiled: September 16, 2022Date of Patent: December 19, 2023Assignee: The University of Western OntarioInventors: Daniel Gelman, Allan Skanes, Maria Drangova
-
Publication number: 20230017179Abstract: A device including a base sized to be hand-held, the base defining a longitudinal axis between first and second opposing longitudinal ends, a cover reversibly fastened to the base in a closed position; a sheath clamp coupled to the base, the sheath clamp capturing a sheath handle of a sheath to immobilize the sheath handle relative to the base, wherein the sheath clamp is an aperture formed in corresponding abutting edges of the cover and the base, the aperture being formed when the cover and the base are in the closed position; a catheter clamp capturing a catheter, a remote end of the catheter configured to deliver a catheterized medical procedure; the catheter clamp aligned to be substantially co-axial with the sheath clamp; and a linear actuator effecting back-and-forth linear motion of the catheter clamp relative to the sheath clamp.Type: ApplicationFiled: September 16, 2022Publication date: January 19, 2023Inventors: Daniel GELMAN, Allan SKANES, Maria DRANGOVA
-
Patent number: 11445977Abstract: A catheter force control system including: a hand-held catheter force control device including: a base sized to be hand-held; a cover reversibly fastened to the base in a closed position; a sheath clamp coupled to the base, the sheath clamp capturing a sheath handle to immobilize the sheath handle relative to the base, the sheath clamp is an aperture formed in corresponding abutting edges of the cover and the base, the aperture being formed when the cover and the base are in the closed position; a catheter clamp capturing a catheter, a remote end of the catheter configured to deliver an ablation therapy; the catheter clamp aligned to be substantially co-axial with the sheath clamp; and a linear actuator effecting linear motion of the catheter clamp relative to the sheath clamp; a force sensor located at the remote end of the catheter, the remote end configured for contact with a target tissue, the force sensor detecting real-time contact force data; a controller for receiving the real-time contact force dataType: GrantFiled: May 15, 2020Date of Patent: September 20, 2022Assignee: THE UNIVERSITY OF WESTERN ONTARIOInventors: Daniel Gelman, Allan Skanes, Maria Drangova
-
Publication number: 20200345305Abstract: A catheter force control system including: a hand-held catheter force control device including: a base sized to be hand-held; a cover reversibly fastened to the base in a closed position; a sheath clamp coupled to the base, the sheath clamp capturing a sheath handle to immobilize the sheath handle relative to the base, the sheath clamp is an aperture formed in corresponding abutting edges of the cover and the base, the aperture being formed when the cover and the base are in the closed position; a catheter clamp capturing a catheter, a remote end of the catheter configured to deliver an ablation therapy; the catheter clamp aligned to be substantially co-axial with the sheath clamp; and a linear actuator effecting linear motion of the catheter clamp relative to the sheath clamp; a force sensor located at the remote end of the catheter, the remote end configured for contact with a target tissue, the force sensor detecting real-time contact force data; a controller for receiving the real-time contact force dataType: ApplicationFiled: May 15, 2020Publication date: November 5, 2020Inventors: Daniel GELMAN, Allan SKANES, Maria DRANGOVA
-
Patent number: 10667752Abstract: A hand-held catheter force control device includes an elongate base sized to be hand-held. The base defines a longitudinal axis between first and second opposing longitudinal ends. A linear actuator is mounted to the base to provide linear motion substantially parallel to the longitudinal axis of the base. A sheath clamp is coupled to the base. The sheath clamp is sized to fixedly capture a sheath handle. A catheter clamp is coupled to the linear actuator. The catheter clamp is sized to fixedly capture a catheter, and is aligned to be substantially co-axial with the sheath clamp. Systems and methods can incorporate the catheter force control device.Type: GrantFiled: February 2, 2017Date of Patent: June 2, 2020Assignee: THE UNIVERSITY OF WESTERN ONTARIOInventors: Daniel Gelman, Allan Skanes, Maria Drangova
-
Patent number: 10534057Abstract: To perform Dixon MRI, generate multi-contrast images, and extract multi-parametric maps, this invention presents a multi-echo gradient echo protocol with two sets of echo trains. An example implementation of the invention at 3 T acquires a short-TE train (?TE˜1.2 ms, TE<10 ms), which is used to map B0 inhomogeneity and proton density fat fraction (FF), and a second—susceptibility sensitive—long-TE train (16 ms<TE<45 ms) will enable quantification of local frequency shift (LFS) and susceptibility. The presented pipeline automatically generates co-registered images and maps with/without fat-suppressed, including magnitude- and complex-based FF map, B0 map, anatomical images, brain mask, R2* map, unwrapped phase maps for each echo, susceptibility-sensitive images (SWI, LFS and quantitative susceptibility) for each echo, mean susceptibility-sensitive images for each echo-train. The invention is directly applicable to whole head/neck, liver, knee or even whole body scans with sliding table.Type: GrantFiled: March 9, 2018Date of Patent: January 14, 2020Inventor: Maria Drangova
-
Patent number: 10441374Abstract: Embodiments relate to systems and methods for catheter manipulation. In particular, systems as described herein can be used to drive a catheter while maintaining control along three degrees of freedom. Systems as described herein can be used in a wide variety of settings, including MRI in which small, non-magnetic robot systems having motors that remain stationary during use are advantageous.Type: GrantFiled: October 8, 2015Date of Patent: October 15, 2019Inventors: Mohammad Ali Tavallaei, Maria Drangova
-
Publication number: 20190107596Abstract: 3D printing in MRI-compatible plastic resin has been used to fabricate and implement a geometric distortion phantom for MRI and CT imaging. The sparse grid structure provides a rigid and accurate phantom with identifiable intersections that are larger than the supporting members, which produces images that are amenable to fully automated quantitative analysis using morphometric erosion, greyscale segmentation and centroiding. This approach produces a 3D vector map of geometric distortion that is useful in clinical applications where geometric accuracy is important, either in routine quality assurance or as a component of distortion correction utilities.Type: ApplicationFiled: December 6, 2018Publication date: April 11, 2019Inventors: David W. Holdsworth, Matthew G. Teeter, Jacques S. Milner, Steven I. Pollmann, Maria Drangova
-
Patent number: 10234521Abstract: Various embodiments of the present disclosure present unwrapping based B0 mapping systems and methods. An initial B0 map is obtained by unwrapping a pseudo-in-phase complex data that is generated from selected echoes of multi-echo gradient echo image data. Global and local phase errors that are present in the initial B0 map are corrected to produce a phase-error-corrected B0 map. A bias frequency shift is employed to produce a corrected fat-fraction map based on the phase-error-corrected B0 map. The corrected fat-fraction map is employed to generate a final B0 map.Type: GrantFiled: April 24, 2015Date of Patent: March 19, 2019Inventors: Junmin Liu, Maria Drangova
-
Publication number: 20190038227Abstract: A hand-held catheter force control device includes an elongate base sized to be hand-held. The base defines a longitudinal axis between first and second opposing longitudinal ends. A linear actuator is mounted to the base to provide linear motion substantially parallel to the longitudinal axis of the base. A sheath clamp is coupled to the base. The sheath clamp is sized to fixedly capture a sheath handle. A catheter clamp is coupled to the linear actuator. The catheter clamp is sized to fixedly capture a catheter, and is aligned to be substantially co-axial with the sheath clamp. Systems and methods can incorporate the catheter force control device.Type: ApplicationFiled: February 2, 2017Publication date: February 7, 2019Inventors: Daniel GELMAN, Allan SKANES, Maria DRANGOVA
-
Patent number: 10180483Abstract: 3D printing in MRI-compatible plastic resin has been used to fabricate and implement a geometric distortion phantom for MRI and CT imaging. The sparse grid structure provides a rigid and accurate phantom with identifiable intersections that are larger than the supporting members, which produces images that are amenable to fully automated quantitative analysis using morphometric erosion, greyscale segmentation and centroiding. This approach produces a 3D vector map of geometric distortion that is useful in clinical applications where geometric accuracy is important, either in routine quality assurance or as a component of distortion correction utilities.Type: GrantFiled: April 23, 2015Date of Patent: January 15, 2019Inventors: David W Holdsworth, Matthew G. Teeter, Jacques S. Milner, Steven I. Pollmann, Maria Drangova
-
Publication number: 20180259607Abstract: To perform Dixon MRI, generate multi-contrast images, and extract multi-parametric maps, this invention presents a multi-echo gradient echo protocol with two sets of echo trains. An example implementation of the invention at 3 T acquires a short-TE train (?TE˜1.2 ms, TE <10 ms), which is used to map B0 inhomogeneity and proton density fat fraction (FF), and a second—susceptibility sensitive—long-TE train (16 ms<TE<45 ms) will enable quantification of local frequency shift (LFS) and susceptibility. The presented pipeline automatically generates co-registered images and maps with/without fat-suppressed, including magnitude- and complex-based FF map, B0 map, anatomical images, brain mask, R2* map, unwrapped phase maps for each echo, susceptibility-sensitive images (SWI, LFS and quantitative susceptibility) for each echo, mean susceptibility-sensitive images for each echo-train. The invention is directly applicable to whole head/neck, liver, knee or even whole body scans with sliding table.Type: ApplicationFiled: March 9, 2018Publication date: September 13, 2018Inventor: Maria Drangova
-
Publication number: 20170304015Abstract: Embodiments relate to systems and methods for catheter manipulation. In particular, systems as described herein can be used to drive a catheter while maintaining control along three degrees of freedom. Systems as described herein can be used in a wide variety of settings, including MRI in which small, non-magnetic robot systems having motors that remain stationary during use are advantageous.Type: ApplicationFiled: October 8, 2015Publication date: October 26, 2017Inventors: Mohammad Ali TAVALLAEI, Maria DRANGOVA
-
Publication number: 20170038446Abstract: Various embodiments of the present disclosure present unwrapping based B0 mapping systems and methods. An initial B0 map is obtained by unwrapping a pseudo-in-phase complex data that is generated from selected echoes of multi-echo gradient echo image data. Global and local phase errors that are present in the initial B0 map are corrected to produce a phase-error-corrected B0 map. A bias frequency shift is employed to produce a corrected fat-fraction map based on the phase-error-corrected B0 map. The corrected fat-fraction map is employed to generate a final B0 map.Type: ApplicationFiled: April 24, 2015Publication date: February 9, 2017Inventors: Junmin LIU, Maria DRANGOVA
-
Patent number: 9513620Abstract: A method of controlling an ultrasonic motor coupled to a motor driver circuit, comprises receiving a temperature signal representing the temperature of the ultrasonic motor, receiving a position signal output by a first encoder representing the position of the ultrasonic motor, calculating an error between the position of the ultrasonic motor represented by the position signal and a target position, calculating a control signal based on the temperature of the ultrasonic motor represented by the temperature signal and the calculated error, and sending the control signal to the motor driver circuit to control the ultrasonic motor.Type: GrantFiled: March 25, 2014Date of Patent: December 6, 2016Assignee: Vital Biomedical Technologies Inc.Inventors: Mohammad Ali Tavallaei, Maria Drangova
-
Patent number: 9344012Abstract: A method for controlling an ultrasonic motor coupled to a motor driver circuit, comprises obtaining a position of a first encoder coupled to the ultrasonic motor, calculating an error between the position of the first encoder and a target position, and sending a control signal to the motor driver circuit to control the ultrasonic motor to adjust the position of the first encoder based the calculated error.Type: GrantFiled: February 11, 2013Date of Patent: May 17, 2016Assignee: Vital Biomedical Technologies Inc.Inventors: Mohammad Ali Tavallaei, Maria Drangova
-
Publication number: 20150309149Abstract: 3D printing in MRI-compatible plastic resin has been used to fabricate and implement a geometric distortion phantom for MRI and CT imaging. The sparse grid structure provides a rigid and accurate phantom with identifiable intersections that are larger than the supporting members, which produces images that are amenable to fully automated quantitative analysis using morphometric erosion, greyscale segmentation and centroiding. This approach produces a 3D vector map of geometric distortion that is useful in clinical applications where geometric accuracy is important, either in routine quality assurance or as a component of distortion correction utilities.Type: ApplicationFiled: April 23, 2015Publication date: October 29, 2015Inventors: David W. Holdsworth, Matthew G. Teeter, Jacques S. Milner, Steven I. Pollmann, Maria Drangova
-
Publication number: 20150270790Abstract: A method of controlling an ultrasonic motor coupled to a motor driver circuit, comprises receiving a temperature signal representing the temperature of the ultrasonic motor, receiving a position signal output by a first encoder representing the position of the ultrasonic motor, calculating an error between the position of the ultrasonic motor represented by the position signal and a target position, calculating a control signal based on the temperature of the ultrasonic motor represented by the temperature signal and the calculated error, and sending the control signal to the motor driver circuit to control the ultrasonic motor.Type: ApplicationFiled: March 25, 2014Publication date: September 24, 2015Applicant: VITAL BIOMEDICAL TECHNOLOGIES INC.Inventors: Mohammad Ali TAVALLAEI, Maria DRANGOVA
-
Patent number: 5485831Abstract: A technique for pulsed-injection of radiographic contrast agent uses a pressurized source of contrast agent interrupted by a rotary valve at rates ranging from 1 to 30 Hz. This produces well-defined boli at the end of the catheter. The position of these boli is recorded by a digital radiographic system and analyzed to produce quantitative measurements of blood velocity and flow rate throughout the cardiac cycle.Type: GrantFiled: November 30, 1993Date of Patent: January 23, 1996Assignee: University Hospital (London) Development CorporationInventors: David W. Holdsworth, Maria Drangova, Aaron Fenster