Patents by Inventor Maria Hottelet Foley

Maria Hottelet Foley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA-BASED LOGIC CIRCUITS WITH RNA BINDING PROTEINS, APTAMERS AND SMALL MOLECULES
    Publication number: 20220395585
    Abstract: Engineered synthetic RNA-based genetic circuits are provided that are regulated exclusively at the post-transcriptional level.
    Type: Application
    Filed: May 3, 2022
    Publication date: December 15, 2022
    Applicants: Massachusetts Institute of Technology, Kyoto University
    Inventors: Ron Weiss, Liliana Wroblewska, Velia Siciliano, Tasuku Kitada, Maria Hottelet Foley, Katie Bodner, Hirohide Saito, Kei Endo, Darrell J. Irvine, Tyler Wagner, Jacob Becraft
  • RNA-based logic circuits with RNA binding proteins, aptamers and small molecules
    Patent number: 11351271
    Abstract: Engineered synthetic RNA-based genetic circuits are provided that are regulated exclusively at the post-transcriptional level.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: June 7, 2022
    Assignees: Massachusetts Institute of Technology, Kyoto University
    Inventors: Ron Weiss, Liliana Wroblewska, Velia Siciliano, Tasuku Kitada, Maria Hottelet Foley, Katie Bodner, Hirohide Saito, Kei Endo, Darrell J. Irvine, Tyler Wagner, Jacob Becraft
  • ENGINEERED HERPES SIMPLEX VIRUS-1 (HSV-1) VECTORS AND USES THEREOF
    Publication number: 20200291428
    Abstract: Provided herein are engineered HSV-1 vectors comprising a modified HSV-1 genome. The engineered HSV-1 vectors can be used to deliver genetic circuits (e.g., up to 100 kb) to cells in vitro or in vivo. Methods of treating or diagnosing a disease (e.g., cancer) using the engineered HSV-1 vectors described herein are also provided.
    Type: Application
    Filed: January 14, 2020
    Publication date: September 17, 2020
    Applicant: Massachusetts Institute of Technology
    Inventors: Ron Weiss, Maria Hottelet Foley, Jin Huh, Ross D. Jones
  • RNA-BASED LOGIC CIRCUITS WITH RNA BINDING PROTEINS, APTAMERS AND SMALL MOLECULES
    Publication number: 20190151474
    Abstract: Engineered synthetic RNA-based genetic circuits are provided that are regulated exclusively at the post-transcriptional level.
    Type: Application
    Filed: September 8, 2015
    Publication date: May 23, 2019
    Applicants: Massachusetts Institute of Technology, Kyoto University
    Inventors: Ron Weiss, Liliana Wroblewska, Velia Siciliano, Tasuku Kitada, Maria Hottelet Foley, Katie Bodner, Hirohide Saito, Kei Endo, Darrell J. Irvine, Tyler Wagner, Jacob Becraft
  • RNA-BASED LOGIC CIRCUITS WITH RNA BINDING PROTEINS, APTAMERS AND SMALL MOLECULES
    Publication number: 20180296702
    Abstract: Engineered synthetic RNA-based genetic circuits are provided that are regulated exclusively at the post-transcriptional level.
    Type: Application
    Filed: September 8, 2015
    Publication date: October 18, 2018
    Applicants: Massachusetts Institute of Technology, Kyoto University
    Inventors: Ron Weiss, Liliana Wroblewska, Velia Siciliano, Tasuku Kitada, Maria Hottelet Foley, Katie Bodner, Hirohide Saito, Kei Endo, Darrell J. Irvine, Tyler Wagner, Jacob Becraft