Patents by Inventor Maria Linton

Maria Linton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis
    Publication number: 20070021354
    Abstract: Compounds of the formula: where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.
    Type: Application
    Filed: June 9, 2006
    Publication date: January 25, 2007
    Inventors: Stacie Canan Koch, Therese Alexander, Benjamin Burke, Tanya Jewell, David Kucera, Maria Linton, Lennert Mitchell, Siegfried Reich, Donald Skalitzky, John Tatlock, Michael Varney, Scott Virgil, Stephen Webber, Stephen Worland, Mark Barvian, Gary Bolton, Frederick Boyer, Jeffrey Machak, Tod Holler, Sean Murphy, Michael Melnick, Vara Josyula
  • INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME
    Publication number: 20060189681
    Abstract: The invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, solvates, prodrugs and metabolites thereof, wherein W, Z, R1 and R2, are as defined herein. The invention also relates to methods of treating Hepatitis C virus in mammals by administering the compounds of formula 1, and to pharmaceutical compositions for treating such disorders, which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.
    Type: Application
    Filed: May 8, 2006
    Publication date: August 24, 2006
    Inventors: Allen Borchardt, Javier Gonzalez, Hui Li, Maria Linton, John Tatlock
  • HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis
    Publication number: 20050250707
    Abstract: Compounds of the formula: where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.
    Type: Application
    Filed: June 20, 2005
    Publication date: November 10, 2005
    Inventors: Stacie Canan Koch, Therese Alexander, Benjamin Burke, Tanya Jewell, David Kucera, Maria Linton, Lennert Mitchell, Siegfried Reich, Donald Skalitzky, John Tatlock, Michael Varney, Scott Virgil, Stephen Webber, Stephen Worland, Mark Barvian, Gary Bolton, Frederick Boyer, Jeffrey Machak, Tod Holler, Sean Murphy, Michael Melnick, Vara Josyula
  • Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same
    Publication number: 20050176701
    Abstract: The invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, solvates, prodrugs and metabolites thereof, wherein W, Z, R1 and R2, are as defined herein. The invention also relates to methods of treating Hepatitis C virus in mammals by administering the compounds of formula 1, and to pharmaceutical compositions for treating such disorders, which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.
    Type: Application
    Filed: November 19, 2003
    Publication date: August 11, 2005
    Inventors: Allen Borchardt, Javier Gonzalez, Hui Li, Maria Linton, John Tatlock
  • HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis
    Publication number: 20030225071
    Abstract: Compounds of the formula: 1
    Type: Application
    Filed: June 11, 2002
    Publication date: December 4, 2003
    Inventors: Stacie S. Canan Koch, Therese N. Alexander, Mark Barvian, Gary Bolton, Fredrick E. Boyer, Benjamin J. Burke, Tod Holler, Tanya M. Jewell, Vara Prasad Josyula, David J. Kucera, Maria A. Linton, Jeffrey J. Machak, Lennert J. Mitchell, Sean T. Murphy, Siegfried H. Reich, Donald J. Skalitzky, John H. Tatlock, Michael D. Varney, Scott C. Virgil, Stephen E. Webber, Stephen T. Worland, Michael Melnick
  • HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis
    Publication number: 20030153507
    Abstract: Compounds of the formula: 1
    Type: Application
    Filed: June 11, 2002
    Publication date: August 14, 2003
    Inventors: Stacie S. Canan-Koch, Therese N. Alexander, Mark Barvian, Gary Bolton, Frederick E. Boyer, Benjamin J. Burke, Tod Holler, Tanya M. Jewell, Vara Prasad Josyula, David J. Kucera, Maria A. Linton, Jeffrey J. Machak, Lennert J. Mitchell, Sean T. Murphy, Siegfried H. Reich, Donald J. Skalitzky, John H. Tatlock, Michael D. Varney, Scott C. Virgil, Stephen E. Webber, Stephen T. Worland, Michael Melnick