Patents by Inventor Mariane MELO

Mariane MELO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11026894
    Abstract: Disclosed herein are lipid nanoparticles comprising 1,2-dioleoyl-3-trimethylammonium propane (DOTAP), 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), cholesterol, and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000](DSPE-PEG2000), compositions including such lipid nanoparticles, and methods of treatment using such lipid nanoparticles and compositions.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: June 8, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Darrell J. Irvine, Ron Weiss, Tasuku Kitada, Mariane Melo, Yuan Zhang
  • Publication number: 20200289629
    Abstract: Disclosed herein are polynucleotides encoding multi-epitope polypeptides and assemblies thereof, and their use for treating or limiting Toxoplasma gondii infection.
    Type: Application
    Filed: June 3, 2020
    Publication date: September 17, 2020
    Inventors: Rima MCLEOD, Kamal EL BISSATI, Ying ZHOU, Jeff ALEXANDER, Lo VANG, Steve REED, Sara M. PAULILLO, Senthil K. RAMAN, Peter BURKHARD, Mariane MELO, Darrel IRVINE, Ron WEISS, Yuan ZHANG, Alessandro SETTE, John SIDNEY, Brian D. LIVINGSTON, Hernan LORENZI
  • Publication number: 20200222332
    Abstract: Disclosed herein are lipid nanoparticles having a specific composition, compositions including such lipid nanoparticles, and methods of treatment using such lipid nanoparticles and compositions.
    Type: Application
    Filed: January 10, 2020
    Publication date: July 16, 2020
    Applicant: Massachusetts Institute of Technology
    Inventors: Darrell J. Irvine, Ron Weiss, Tasuku Kitada, Mariane Melo, Yuan Zhang
  • Publication number: 20190282679
    Abstract: Disclosed herein are polynucleotides encoding multi-epitope polypeptides and assemblies thereof, and their use for treating or limiting Toxoplasma gondii infection.
    Type: Application
    Filed: April 14, 2017
    Publication date: September 19, 2019
    Inventors: Rima MCLEOD, Kamal EL BISSATI, Ying ZHOU, Jeff ALEXANDER, Lo VANG, Steve REED, Sara M. PAULILLO, Senthil K. RAMAN, Peter BURKHARD, Mariane MELO, Darrel IRVINE, Ron WEISS, Yuan ZHANG, Alessandro SETTE, John SIDNEY, Brian D. LIVINGSTON, Hernan LORENZI