Patents by Inventor Mariappan S. Nadar

Mariappan S. Nadar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230298230
    Abstract: Various techniques of reconstructing multiple Magnetic Resonance Imaging, MRI, images for multiple slices based on an MRI measurement dataset that is acquired using a simultaneous multi-slice protocol and undersampling and K-space are disclosed. A convolutional neural network can be used to implement a regularization operation of an iterative optimization for the reconstruction, i.e., an unrolled neural network or variational neural network. A combination with Dixon imaging, i.e., separation of multiple chemical species, is disclosed.
    Type: Application
    Filed: March 18, 2022
    Publication date: September 21, 2023
    Inventors: Esther Raithel, Boris Mailhe, Mahmoud Mostapha, Jan Fritz, Florian Knoll, Marcel Dominik Nickel, Gregor Körzdörfer, Inge Brinkmann, Mariappan S. Nadar
  • Publication number: 20230298162
    Abstract: For reconstruction in medical imaging using phase correction, a machine learning model is trained for reconstruction of an image. The reconstruction may be for a sequence without repetitions or may be for a sequence with repetitions. Where repetitions are used, rather than using just a loss for that repetition in training, the loss based on an aggregation of images reconstructed from multiple repetitions may used to train the machine learning model. In either approach, a phase correction is applied in machine training. A phase map is extracted from output of the model in training or extracted from the ground truth of the training data. The phase correction, based on the phase map, is applied to the ground truth and/or the output of the model in training. The resulting machine-learned model may better reconstruct an image as a result of having been trained using phase correction.
    Type: Application
    Filed: March 17, 2022
    Publication date: September 21, 2023
    Inventors: Simon Arberet, Marcel Dominik Nickel, Thomas Benkert, Mariappan S. Nadar
  • Publication number: 20230274418
    Abstract: For reconstruction in medical imaging, self-consistency using data augmentation is improved by including data consistency. Artificial intelligence is trained based on self-consistency and data consistency, allowing training without supervision. Fully sampled data and/or ground truth is not needed but may be used. The machine-trained model is less likely to reconstruct images with motion artifacts, and/or the training data may be more easily gathered by not requiring full sampling.
    Type: Application
    Filed: February 25, 2022
    Publication date: August 31, 2023
    Inventors: Simon Arberet, Mariappan S. Nadar, Mahmoud Mostapha, Dorin Comaniciu
  • Publication number: 20230255506
    Abstract: A method of scanning an organ structure of a patient using magnetic resonance imaging, includes scanning, in a first scanning process, the patient to obtain first image data indicative of at least the organ structure of the patient. The method further includes determining, based on the first image data, one or more parameters obtain second image data indicative of at least the organ structure of the patient. The first scanning process includes a first quality of imaging scan, the second scanning process includes a second quality of imaging scan, and the first quality of imaging scan is higher than the second quality of imaging scan.
    Type: Application
    Filed: February 10, 2023
    Publication date: August 17, 2023
    Applicant: Siemens Healthcare GmbH
    Inventors: Andreas Greiser, Venkata Veerendranadh Chebrolu, Boris Mailhe, Mariappan S. Nadar, Daniel Rinck
  • Publication number: 20230253095
    Abstract: For data analytics in magnetic resonance (MR) scanning, the scanning configuration information and the resulting raw data are directly used to determine the analytics or clinical decision. Artificial intelligence provides a value for a clinical finding characteristic of the patient based on the raw data from scanning and the controls used to scan, allowing the value to be based on all of the information content of the scan results. Reconstruction is not needed, allowing for simpler hardware, such as hardware with less homogeneous B0 and/or B1 fields than the norm and/or non-linear gradients.
    Type: Application
    Filed: May 31, 2022
    Publication date: August 10, 2023
    Inventors: Boris Mailhe, Dorin Comaniciu, Ali Kamen, Bin Lou, Mariappan S. Nadar, Andreas Greiser, Venkata Veerendranadh Chebrolu
  • Publication number: 20230252623
    Abstract: Systems and methods for performing a quality assessment of a medical imaging analysis task are provided. At least one low-field MRI (magnetic resonance imaging) quality assurance imaging data of the patient is received. A quality assessment of a medical imaging analysis task is performed based on the at least one low-field MRI quality assurance imaging data using one or more machine learning based networks. Results of the quality assessment are output.
    Type: Application
    Filed: December 8, 2022
    Publication date: August 10, 2023
    Inventors: Bin Lou, Ali Kamen, Boris Mailhe, Mariappan S. Nadar, Dorin Comaniciu
  • Publication number: 20230248255
    Abstract: For autonomous MR scanning for a given medical test, a simplified MR scanner may be used without or will little input or control by a technologist (e.g., by a physician, radiologist, or person trained in MR scanner operation). The MR scanner autonomously positions, scans, checks quality, analyzes, and/or outputs an answer to a diagnostic question with or without an MR image. Scan analysis, based on artificial intelligence, allows for on-going or on-the-fly alteration of the scanning configuration to acquire the data desired to answer the diagnostic question. By using a simplified MR scanner, both position of the patient relative to the MR scanner and localization of the scan by the MR scanner are jointly solved. Sensors may sense a patient in a scan position where the reduced radio frequency requirements allow for a more open bore.
    Type: Application
    Filed: June 16, 2022
    Publication date: August 10, 2023
    Inventors: Boris Mailhe, Dorin Comaniciu, Ali Kamen, Mariappan S. Nadar, Bin Lou, Andreas Greiser, Venkata Veerendranadh Chebrolu
  • Publication number: 20230221392
    Abstract: For reconstruction of an image in MRI, unsupervised training (i.e., data-driven) based on a scan of a given patient is used to reconstruct model parameters, such as estimating values of a contrast model and a motion model based on fit of images generated by the models for different readouts and times. The models and the estimated values from the scan-specific unsupervised training are then used to generate the patient image for that scan. This may avoid artifacts from binning different readouts together while allowing for scan sequences using multiple readouts.
    Type: Application
    Filed: January 11, 2022
    Publication date: July 13, 2023
    Inventors: Boris Mailhe, Dorin Comaniciu, Simon Arberet, Nirmal Janardhanan, Mariappan S. Nadar, Hongki Lim, Mahmoud Mostapha
  • Publication number: 20230108663
    Abstract: For magnetic resonance (MR) reconstruction using artificial intelligence (AI), the AI-based reconstruction for MR imaging systems is offloaded to one or more servers. A remote server performs AI-based reconstruction. A library of recent, old, custom, and/or publicly available AI-based reconstruction processes may be rapidly deployed and available to the server, which has the memory and processing resources for AI-based reconstruction. Load balancing of the data and/or between servers may improve performance.
    Type: Application
    Filed: October 6, 2021
    Publication date: April 6, 2023
    Inventors: Nirmal Janardhanan, Laszlo Lazar, Boris Mailhe, Simon Arberet, Mariappan S. Nadar, Dorin Comaniciu, Kelvin Chow, Michael Bush
  • Publication number: 20230095222
    Abstract: For reconstruction in medical imaging, user control of a characteristic (e.g., noise level) of the reconstructed image is provided. A machine-learned model alters the reconstructed image to enhance or reduce the characteristic. The user selected level of characteristic is then provided by combining the reconstructed image with the altered image based on the input level of the characteristic. Personalized or more controllable impression for medical imaging reconstruction is provided without requiring different reconstructions.
    Type: Application
    Filed: September 24, 2021
    Publication date: March 30, 2023
    Inventors: Mahmoud Mostapha, Boris Mailhe, Marcel Dominik Nickel, Gregor Körzdörfer, Simon Arberet, Mariappan S. Nadar
  • Publication number: 20230093752
    Abstract: One or more tractograms of a global tractography of a tissue of interest are determined. At least one instance of diffusion magnetic resonance imaging data of the tissue of interest is obtained. A trained machine-learning algorithm generates the one or more tractograms based on the at least one instance of the diffusion magnetic resonance imaging data.
    Type: Application
    Filed: September 8, 2022
    Publication date: March 23, 2023
    Inventors: Mahmoud Mostapha, Boris Mailhe, Dorin Comaniciu, Nirmal Janardhanan, Simon Arberet, Hongki Lim, Mariappan S. Nadar
  • Publication number: 20230079353
    Abstract: For correction of an image from an imaging system, an inverse solution uses an imaging prior as a regularizer and a physics model of the imaging system. An invertible network is used as the deep-learnt generative model in the regularizer of the inverse solution with the physics model of the degradation behavior of the imaging system. The prior model based on the invertible network provides a closed-form expression of the prior probability, resulting in a more versatile or accurate probability prediction.
    Type: Application
    Filed: September 14, 2021
    Publication date: March 16, 2023
    Inventors: Boris Mailhe, Mariappan S. Nadar, Simon Arberet, Mahmoud Mostapha
  • Publication number: 20230085254
    Abstract: For reconstruction in medical imaging using a scan protocol with repetition, a machine learning model is trained for reconstruction of an image for each repetition. Rather than using a loss for that repetition in training, the loss based on an aggregation of images reconstructed from multiple repetitions is used to train the machine learning model. This loss for reconstruction of one repetition based on aggregation of reconstructions for multiple repetitions is based on deep set-based deep learning. The resulting machine-learned model may better reconstruct an image from a given repetition and/or a combined image from multiple repetitions than a model learned from a loss per repetition.
    Type: Application
    Filed: September 13, 2021
    Publication date: March 16, 2023
    Inventors: Simon Arberet, Boris Mailhe, Thomas Benkert, Marcel Dominik Nickel, Mahmoud Mostapha, Mariappan S. Nadar
  • Patent number: 11585876
    Abstract: A system is provided for MRI coil sensitivity estimation and reconstruction At least two cascades of regularization networks are serially connected such that the output of a cascade is used as input of a following cascade, at least two deepsets coil sensitivity map networks are serially connected such that the output of a deepsets coil sensitivity map network is used as input of a following deepsets coil sensitivity map network (CR), and wherein the outputs of the deepsets coil sensitivity map networks are also used as inputs for the cascades.
    Type: Grant
    Filed: January 17, 2022
    Date of Patent: February 21, 2023
    Assignee: Siemens Healthcare GmbH
    Inventors: Mahmoud Mostapha, Boris Mailhe, Mariappan S. Nadar, Simon Arberet, Marcel Dominik Nickel
  • Patent number: 11580381
    Abstract: For machine training and application of a trained complex-valued machine learning model, an activation function of the machine learning model, such as a neural network, includes a learnable parameter that is complex or defined in a complex domain with two dimensions, such as real and imaginary or magnitude and phase dimensions. The complex learnable parameter is trained for any of various applications, such as MR fingerprinting, other medical imaging, or non-medical uses.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: February 14, 2023
    Assignee: Siemens Healthcare GmbH
    Inventors: Guillaume Daval Frerot, Xiao Chen, Simon Arberet, Boris Mailhe, Mariappan S. Nadar, Peter Speier, Mathias Nittka
  • Publication number: 20220334204
    Abstract: Object specific in-homogeneities in an MRI system are corrected. Prescan information available at the MR imaging system is determined. The prescan information includes at least object specific information of an object located in the MR imaging system from which an MR image is to be generated. The prescan information does not include a B1 map of the MRI system with the object being present in the MR imaging system. The prescan information is applied to a trained machine learning module provided at the MRI system. The trained machine learning module determines and generates shimming information as output. The shimming information is applied to a shimming module of the MR imaging system, wherein the shimming module uses the shimming information to generate a corrected magnetic field B0.
    Type: Application
    Filed: March 21, 2022
    Publication date: October 20, 2022
    Inventors: Birgi Tamersoy, Boris Mailhe, Vivek Singh, Ankur Kapoor, Mariappan S. Nadar
  • Patent number: 11435419
    Abstract: For radial sampling in magnetic resonance imaging (MRI), a rescaling factor is determined from k-space data for each coil. The rescale factor is inversely proportional to the streak energy in the k-space data. The k-space data from the coils is rescaled for reconstruction, such as weighting the k-space data by the rescale factor in a data consistency term of iterative reconstruction. The rescale factor is additionally or alternatively used to determine a correction field for correction of intensity bias applied to intensities in the image-object space after reconstruction. These approaches may result in a diagnostically useful bias-corrected image with reduced streak artifact while benefiting from the efficient computation (i.e., computer operates to reconstruct more quickly).
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: September 6, 2022
    Assignee: Siemens Healthcare GmbH
    Inventors: Sajan Goud Lingala, Boris Mailhe, Nirmal Janardhanan, Jyotipriya Das, Robert Grimm, Marcel Dominik Nickel, Mariappan S. Nadar
  • Patent number: 11422217
    Abstract: For reconstruction in medical imaging, such as reconstruction in MR imaging, a high-resolution image is reconstructed using a generator of a progressive generative adversarial network (PGAN or progressive GAN). In machine training the network, both the generator and discriminator of the GAN are grown progressively: starting from a low resolution, new layers are added that model finer details as training progresses. The resulting generator may be better able to handle high-resolution information than a generator of a GAN.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: August 23, 2022
    Assignee: Siemens Healthcare GmbH
    Inventors: Boris Mailhe, Simon Arberet, Anatole Louis Jerome Moreau, Mariappan S. Nadar
  • Publication number: 20220252683
    Abstract: A system is provided for MRI coil sensitivity estimation and reconstruction At least two cascades of regularization networks are serially connected such that the output of a cascade is used as input of a following cascade, at least two deepsets coil sensitivity map networks are serially connected such that the output of a deepsets coil sensitivity map network is used as input of a following deepsets coil sensitivity map network (CR), and wherein the outputs of the deepsets coil sensitivity map networks are also used as inputs for the cascades.
    Type: Application
    Filed: January 17, 2022
    Publication date: August 11, 2022
    Inventors: Mahmoud Mostapha, Boris Mailhe, Mariappan S. Nadar, Simon Arberet, Marcel Dominik Nickel
  • Publication number: 20220215600
    Abstract: A computer-implemented method includes, based on an input dataset defining an input image, determining a reconstructed image using a reconstruction algorithm, and executing a data-consistency operation for enforcing consistency between the input image and the reconstructed image. The data-consistency operation determines, for multiple K-space positions at which the input dataset comprises respective source data, a contribution of respective K-space values associated with the input dataset to a K-space representation of the reconstructed image.
    Type: Application
    Filed: December 7, 2021
    Publication date: July 7, 2022
    Inventors: Simon Arberet, Mariappan S. Nadar, Boris Mailhe, Mahmoud Mostapha, Nirmal Janardhanan