Patents by Inventor Marie-Françoise Rosier-Montus

Marie-Françoise Rosier-Montus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acids encoding a human PAP1 polypeptide
    Patent number: 8273548
    Abstract: The present invention relates to novel compounds and their uses, in particular their pharmaceutical or diagnostic uses or their use as pharmacological targets. More particularly, the present invention relates to a novel protein, referred to as PAP1, as well as to novel peptides and compounds which are capable of modulating, at least partially, the activity of parkin.
    Type: Grant
    Filed: March 28, 2006
    Date of Patent: September 25, 2012
    Assignee: Aventis Pharma S.A.
    Inventors: Han Koutnikova, Alexis Brice, Alain Fournier, Laurent Pradier, Catherine Prades, Isabelle Arnould-Reguigne, Marie-Françoise Rosier-Montus, Olga Corti
  • Regulatory nucleic acid for the ABC1 gene, molecules modifying its activity and therapeutic uses
    Patent number: 7378274
    Abstract: The present invention concerns a nucleic acid which is capable of regulating the transcription of the ABC1 gene, which is a causal gene for pathologies linked to a dysfunctioning of cholesterol metabolism, inducing diseases such as atherosclerosis. The invention also relates to nucleotide constructs comprising a polynucleotide which encodes a polypeptide or a nucleic acid of interest, placed under the control a regulatory nucleic acid for the ABC1 gene. The invention also relates to recombinant vectors, transformed host cells and nonhuman transgenic mammals comprising a nucleic acid which regulates the transcription of the ABC1 gene or an abovementioned nucleotide construct, as well as methods for screening molecules or substances which are capable of modifying the activity of the regulatory nucleic acid for the ABC1 gene.
    Type: Grant
    Filed: May 2, 2001
    Date of Patent: May 27, 2008
    Assignee: Aventis Pharma S.A.
    Inventors: Marie-Françoise Rosier-Montus, Catherine Prades, Cendrine Lemoine, Laurent Naudin, Patrice Denefle, Nicolas Duverger, Bryan Brewer, Alan Remaley, Sylvia Santamarina-Fojo
  • Compositions which can be used for regulating the activity of parkin
    Publication number: 20060287230
    Abstract: The present invention relates to novel compounds and their uses, in particular their pharmaceutical or diagnostic uses or their use as pharmacological targets. More particularly, the present invention relates to a novel protein, referred to as PAP1, as well as to novel peptides and compounds which are capable of modulating, at least partially, the activity of parkin.
    Type: Application
    Filed: March 28, 2006
    Publication date: December 21, 2006
    Inventors: Hana Koutnikova, Alexis Brice, Alain Fournier, Laurent Pradier, Catherine Prades, Isabelle Arnould-Reguigne, Marie-Francoise Rosier-Montus, Olga Corti
  • Compositions which can be used for regulating the activity of parkin
    Patent number: 7132396
    Abstract: The present invention relates to novel compounds and their uses, in particular their pharmaceutical or diagnostic uses or their use as pharmacological targets. More particularly, the present invention relates to a novel protein, referred to as PAP1, as well as to novel peptides and compounds which are capable of modulating, at least partially, the activity of parkin.
    Type: Grant
    Filed: February 20, 2001
    Date of Patent: November 7, 2006
    Assignee: Aventis Pharma S.A.
    Inventors: Hana Koutnikova, Alexis Brice, Alain Fournier, Laurent Pradier, Catherine Prades, Isabelle Arnould-Reguigne, Marie-Françoise Rosier-Montus, Olga Corti
  • Nucleic and proteinic acids corresponding to human gene ABC1
    Publication number: 20040185456
    Abstract: The invention relates to nucleic acids corresponding to different exons and introns of gene ABC1 which is shown to be a gene causing pathologies linked to cholesterol metabolism dysfunction causing diseases such as atherosclerosis, more particularly perturbation of reverse cholesterol transport and more particularly the FHD's such as Tangier Disease
    Type: Application
    Filed: June 18, 2003
    Publication date: September 23, 2004
    Applicant: Aventis Pharma S.A.
    Inventors: Patrice Denefle, Marie-Francoise Rosier-Montus, Isabelle Arnould-Reguigne, Catherine Prades, Laurent Naudin, Cendrine Lemoine, Nicolas Duverger, Stephan Rust, Gerd Assmann, Harald Funke, H. Bryan Brewer
  • Nucleic acids of the human ABCA12 gene, vectors containing such nucleic acids and uses thereof
    Publication number: 20030087246
    Abstract: The present invention relates to a novel human ABCA12 gene as well as cDNAs encoding the novel full and short length ABCA12 proteins. The invention also relates to vectors and recombinants host cells comprising such nucleic acids, nucleotide probes and primers, and means for the detection of polymorphisms and mutations in the ABCA12 gene or in the corresponding protein produced by the allelic form of the ABCA12 gene.
    Type: Application
    Filed: February 12, 2002
    Publication date: May 8, 2003
    Inventors: Isabelle Arnould-Reguigne, Catherine Prades, Laurent Naudin, Cendrine Lemoine, Michael Dean, Patrice Denefle, Marie-Francoise Rosier-Montus
  • Nucleic acid for regulating the ABCA7 gene, molecules modulating its activity and therapeutic applications
    Publication number: 20030077591
    Abstract: The present invention relates to nucleic acid sequences that regulate the transcription of the ABCA7 gene, which may be involved in the metabolism of lipids in hematopoietic tissues, as well as in cell signaling mechanisms linked to the immune reaction and to inflammation. The invention also relates to polypeptides and polynucleotides that may be involved in diseases associated with the genetic locus q13 of chromosome 19.
    Type: Application
    Filed: October 24, 2001
    Publication date: April 24, 2003
    Inventors: Patrice Denefle, Marie-Francoise Rosier-Montus, Catherine Prades, Isabelle Arnould-Reguigne, Jose Osorio Y Fortea, Nicolas Duverger, Giovanna Chimini
  • Polymorphic sequences of the human ABCA1 gene, their uses, and detection methods and kits therefor
    Publication number: 20030056234
    Abstract: The present invention relates to isolated nucleic acids encoding the ABCA1 transporter protein and comprising polymorphic sequence variations, and to peptides which are derived from the human ABCA1 transporter and which contain polymorphic amino acids.
    Type: Application
    Filed: October 31, 2001
    Publication date: March 20, 2003
    Inventors: Patrice Denefle, Marie-Francoise Rosier-Montus, Isabelle Arnould-Reguigne, Nicolas Duverger, Francois Cambien
  • Nucleic acids of the human ABCA5, ABCA6, ABCA9, AND ABCA10 Genes, vectors containing such nucleic acids, and uses thereof
    Publication number: 20030044895
    Abstract: The present invention relates to nucleic acids corresponding to various exons of ABCA5, ABCA6, ABCA9, and ABCA10 genes as well as cDNAs encoding the novel full length of ABCA5, ABCA6, ABCA9, and ABCA10 proteins. The invention also relates to means for the detection of polymorphisms in general, and of mutations in particular, in the ABCA5, ABCA6, ABCA9, and ABCA10 genes or in the corresponding protein produced by the allelic form of the ABCA5, ABCA6, ABCA9, and ABCA10 genes.
    Type: Application
    Filed: December 7, 2001
    Publication date: March 6, 2003
    Inventors: Patrice Denefle, Marie-Francoise Rosier-Montus, Catherine Prades, Isabelle Arnould-Reguigne, Nicolas Duverger, Rando Allikmets, Michael Dean
  • Compositions which can be used for regulating the activity of parkin
    Publication number: 20020155577
    Abstract: The present invention relates to novel compounds and their uses, in particular their pharmaceutical or diagnostic uses or their use as pharmacological targets. More particularly, the present invention relates to a novel protein, referred to as PAP1, as well as to novel peptides and compounds which are capable of modulating, at least partially, the activity of parkin.
    Type: Application
    Filed: February 20, 2001
    Publication date: October 24, 2002
    Inventors: Hana Koutnikova, Alexis Brice, Alain Fournier, Laurent Pradier, Catherine Prades, Isabelle Arnould-Reguigne, Marie-Francoise Rosier-Montus, Olga Corti
  • Regulatory nucleic acid for the ABC1 gene, molecules modifying its activity and therapeutic uses
    Publication number: 20020146792
    Abstract: The present invention concerns a nucleic acid which is capable of regulating the transcription of the ABC1 gene, which is a causal gene for pathologies linked to a dysfunctioning of cholesterol metabolism, inducing diseases such as atherosclerosis.
    Type: Application
    Filed: May 2, 2001
    Publication date: October 10, 2002
    Inventors: Marie-Francoise Rosier-Montus, Catherine Prades, Cendrine Lemoine, Laurent Naudin, Patrice Denefle, Nicolas Duverger, Bryan Brewer, Alan Remaley, Sylvia Santamarina-Fojo