Abstract: A manufacturing process of a fibrous preform for a composite material includes creating a fibrous texture by three-dimensional or multilayer weaving between a plurality of weft layers and warp layers, the fibrous texture including an extra-thick portion having a sacrificial portion and a useful portion adjacent to the sacrificial portion in the warp direction, the sacrificial portion, placing the fibrous texture in a forming toolset, shaping the fibrous texture so as to obtain a fibrous preform having a sacrificial portion and an adjacent useful portion, removing the sacrificial portion from the fibrous preform. When weaving the fibrous blank, one or more expansion elements are inserted into the weft layers located at the core of the sacrificial portion of the fibrous texture. Each expansion element has a cross-section greater than the cross-section or count of the weft threads or strands present in the useful portion.

Abstract: A method of fabricating a fiber structure by multilayer three-dimensional weaving between a plurality of weft yarns and of warp yarns, the fiber structure having at least first and second portions that are adjacent in the warp direction, the first portion presenting, in a direction perpendicular to the warp and weft directions, a thickness greater than the thickness of the second portion, includes making the first portion using a step of three-dimensionally weaving warp and weft layers in which a fiber fabric is formed in the form of a Mock-Leno weave grid in a core of the first portion together with skins at a surface of the first portion, a weave of the skins being modified locally so as to deflect certain warp yarns from said skins and weave them with the fiber fabric in the form of the Mock-Leno weave grid.

Abstract: A manufacturing process of a fibrous preform for a composite material includes creating a fibrous texture by three-dimensional or multilayer weaving between a plurality of weft layers and warp layers, the fibrous texture including an extra-thick portion having a sacrificial portion and a useful portion adjacent to the sacrificial portion in the warp direction, the sacrificial portion, placing the fibrous texture in a forming toolset, shaping the fibrous texture so as to obtain a fibrous preform having a sacrificial portion and an adjacent useful portion, removing the sacrificial portion from the fibrous preform. When weaving the fibrous blank, one or more expansion elements are inserted into the weft layers located at the core of the sacrificial portion of the fibrous texture. Each expansion element has a cross-section greater than the cross-section or count of the weft threads or strands present in the useful portion.

Abstract: The invention relates to a three-dimensionally woven multilayer fibrous structure (20) having the same number of warp yarns woven at any level along the warp direction, the fibrous structure (20) comprising, in the warp direction, a first part (22) and a second part (24), the first part (22) having a thickness measured in a direction perpendicular to the warp and weft directions, greater than the second part (24), characterised in that the spacing between two weft planes along the warp direction is greater in the second part than in the first part (22), and in that the number of weft yarns is lower in the second part (24) than in the first part (22).

Abstract: The invention relates to an energy-releasing composite material comprising at least one nanoporous material and at least one inorganic oxidant, characterised in that said nanoporous material is a nanoporous carbon material.

Abstract: The invention relates to a method of fabricating a turbine engine blade out of composite material comprising fiber reinforcement densified by a matrix, the blade comprising an airfoil, a platform situated at a longitudinal end of the airfoil, and at least one functional element projecting from the outside face of the platform. The method comprises: making a single-piece fiber blank by multilayer weaving; shaping the fiber blank to obtain a single-piece fiber preform having a first portion (302) forming a preform for the blade airfoil (320) and a second portion (314) forming a preform for the platform (340) and at least one preform for a functional element (352; 354); and densifying the fiber preform with a matrix. The second preform portion comprises a set of yarn layers interlinked by weaving with at least one zone of non-interlinking being provided to make it possible to deploy the functional element preform relative to the first platform preform.

Abstract: A fiber structure includes a plurality of weft layers and a plurality of warp layers interlinked with three-dimensional or multilayer weaving, the fiber structure including at least first and second portions that are adjacent in the warp direction, the first portion presenting thickness in a direction perpendicular to the warp and weft directions that is greater than the thickness of the second portion. The weft layers situated in the core of the first portion of the fiber structure include braids. The weft layers extending on either side of the weft layers including the braids and going as far as the skin of the first portion include yarns or strands, the braids presenting a section greater than the section of the yarns or strands.

Abstract: A method of fabricating a fiber structure by multilayer three-dimensional weaving between a plurality of weft yarns and of warp yarns, the fiber structure having at least first and second portions that are adjacent in the warp direction, the first portion presenting, in a direction perpendicular to the warp and weft directions, a thickness greater than the thickness of the second portion, includes making the first portion using a step of three-dimensionally weaving warp and weft layers in which a fiber fabric is formed in the form of a Mock-Leno weave grid in a core of the first portion together with skins at a surface of the first portion, a weave of the skins being modified locally so as to deflect certain warp yarns from said skins and weave them with the fiber fabric in the form of the Mock-Leno weave grid.

Abstract: A fiber structure includes a plurality of weft layers and of warp layers interlinked by multilayer three-dimensional weaving, the fiber structure having at least first and second portions that are adjacent in the warp direction, the first portion presenting, in a direction perpendicular to the warp and weft directions, a thickness that is greater than the thickness of the second portion, wherein the first portion has at its core at least one fiber fabric obtained by three-dimensional weaving of warp yarns and weft yarns in the form of a Mock Leno weave grid, the at least one fabric being present between two skins present at the surface of the first portion and being linked to the skins by warp yarns belonging to the skins that are locally deflected into the fabric.

Abstract: A fiber structure includes a plurality of weft layers and of warp layers interlinked by multilayer three-dimensional weaving, the fiber structure having at least first and second portions that are adjacent in the warp direction, the first portion presenting, in a direction perpendicular to the warp and weft directions, a thickness that is greater than the thickness of the second portion, wherein the first portion has at its core at least one fiber fabric obtained by three-dimensional weaving of warp yarns and weft yarns in the form of a Mock Leno weave grid, the at least one fabric being present between two skins present at the surface of the first portion and being linked to the skins by warp yarns belonging to the skins that are locally deflected into the fabric.

Abstract: The invention relates to a method of fabricating a turbine engine blade out of composite material comprising fiber reinforcement densified by a matrix, the blade comprising an airfoil, a platform situated at a longitudinal end of the airfoil, and at least one functional element projecting from the outside face of the platform. The method comprises: making a single-piece fiber blank by multilayer weaving; shaping the fiber blank to obtain a single-piece fiber preform having a first portion (302) forming a preform for the blade airfoil (320) and a second portion (314) forming a preform for the platform (340) and at least one preform for a functional element (352; 354); and densifying the fiber preform with a matrix. The second preform portion comprises a set of yarn layers interlinked by weaving with at least one zone of non-interlinking being provided to make it possible to deploy the functional element preform relative to the first platform preform.

Abstract: A method of fabricating a composite material part including fiber reinforcement and a ceramic matrix present in the pores of the fiber reinforcement, the method including a) forming the fiber reinforcement by three-dimensionally weaving ceramic yarns, the fiber reinforcement as formed in this way presenting an interlock weave; b) forming a first ceramic matrix phase in the pores of the fiber reinforcement; c) after performing step b), introducing into the pores of the fiber reinforcement a powder that includes a mixture of SiC particles and of carbon particles; and d) infiltrating the fiber reinforcement obtained after performing step c), with an infiltration composition in the molten state including at least silicon so as to form a second ceramic matrix phase in the pores of the fiber reinforcement, thereby obtaining the composite material part.

Abstract: The invention relates to a method of fabricating a turbine engine blade out of composite material comprising fiber reinforcement densified by a matrix, the blade comprising an airfoil, a platform situated at a longitudinal end of the airfoil, and at least one functional element projecting from the outside face of the platform. The method comprises: making a single-piece fiber blank by multilayer weaving; shaping the fiber blank to obtain a single-piece fiber preform having a first portion (302) forming a preform for the blade airfoil (320) and a second portion (314) forming a preform for the platform (340) and at least one preform for a functional element (352; 354); and densifying the fiber preform with a matrix. The second preform portion comprises a set of yarn layers interlinked by weaving with at least one zone of non-interlinking being provided to make it possible to deploy the functional element preform relative to the first platform preform.

Abstract: Antibodies are provided which specifically bind human and Macaca fascicularis lysosomal-associated membrane protein 1 (LAMP1) proteins and immunoconjugates comprising said antibodies conjugated or linked to a growth inhibitory agent. Pharmaceutical compositions comprising antibodies or immunoconjugates of the invention and use of the antibodies or immunoconjugates for the treatment of cancer are also provided, as well as LAMP1 antibodies, isolated nucleic acids, vectors and host cells comprising a sequence encoding said antibodies and the use of said antibody as a diagnostic tool. The application further provides for the detection of LAMP1 gene amplification or gain in cancer cells leading to the determination if patients with cancer are likely to respond to anti-LAMP1 therapy.

Abstract: A fiber structure includes a plurality of weft layers and a plurality of warp layers interlinked with three-dimensional or multilayer weaving, the fiber structure including at least first and second portions that are adjacent in the warp direction, the first portion presenting thickness in a direction perpendicular to the warp and weft directions that is greater than the thickness of the second portion. The weft layers situated in the core of the first portion of the fiber structure include braids. The weft layers extending on either side of the weft layers including the braids and going as far as the skin of the first portion include yarns or strands, the braids presenting a section greater than the section of the yarns or strands.

Abstract: Antibodies are provided which specifically bind human and Macaca fascicularis lysosomal-associated membrane protein 1 (LAMP1) proteins and immunoconjugates comprising said antibodies conjugated or linked to a growth inhibitory agent. Pharmaceutical compositions comprising antibodies or immunoconjugates of the invention and use of the antibodies or immunoconjugates for the treatment of cancer are also provided, as well as LAMP1 antibodies, isolated nucleic acids, vectors and host cells comprising a sequence encoding said antibodies and the use of said antibody as a diagnostic tool. The application further provides for the detection of LAMP1 gene amplification or gain in cancer cells leading to the determination if patients with cancer are likely to respond to anti-LAMP1 therapy. Anti-LAMP1 therapeutic agent for use for treating cancer in a patient harboring LAMP1 gene copy number gain in cancer cells is further provided.

Abstract: The invention relates to a method of fabricating a turbine engine blade out of composite material comprising fiber reinforcement densified by a matrix, the blade comprising an airfoil, a platform situated at a longitudinal end of the airfoil, and at least one functional element projecting from the outside face of the platform. The method comprises: making a single-piece fiber blank by multilayer weaving; shaping the fiber blank to obtain a single-piece fiber preform having a first portion (302) forming a preform for the blade airfoil (320) and a second portion (314) forming a preform for the platform (340) and at least one preform for a functional element (352; 354); and densifying the fiber preform with a matrix. The second preform portion comprises a set of yarn layers interlinked by weaving with at least one zone of non-interlinking being provided to make it possible to deploy the functional element preform relative to the first platform preform.

Abstract: Antibodies are provided which specifically bind human and Macaca fascicularis lysosomal-associated membrane protein 1 (LAMP1) proteins and immunoconjugates comprising said antibodies conjugated or linked to a growth inhibitory agent. Pharmaceutical compositions comprising antibodies or immunoconjugates of the invention and use of the antibodies or immunoconjugates for the treatment of cancer are also provided, as well as LAMP1 antibodies, isolated nucleic acids, vectors and host cells comprising a sequence encoding said antibodies and the use of said antibody as a diagnostic tool. The application further provides for the detection of LAMP1 gene amplification or gain in cancer cells leading to the determination if patients with cancer are likely to respond to anti-LAMP1 therapy.

Abstract: The invention relates to a method of manufacturing locks for doors of a plurality of models of motor vehicles, each lock comprising a latch (1) which is rotatable about an axis (A) and which is associated with a pawl (2) rotatable about an axis (B), and also a mechanical and/or electrical transmission arrangement for carrying out an identical list of commands, the positioning of the fastening points (3, 4, 5) of these locks being identical, and the relative positioning of their “S point” (S1, S2) being different. According to the invention, said mechanical and/or electrical transmission arrangement of each of the locks is identical and only the assembly consisting of the latch and the associated pawl is different for each model of vehicles, in order to achieve said positioning of the “S point”.

Abstract: Lock comprising a rotary latch and a pawl for retaining the latch; external opening control rod and internal opening control rod for acting on the pawl by way of an intermediate lever and an electric drive. The intermediate lever has one end connected to the pawl. The lever being articulated in such a way as to be able to pivot at least about two different axes forming an angle between them. A pivoting of the lever about a first direction permits the locking function to be performed, a pivoting of the lever about the second direction permits the child safety function to be performed, and a combined pivoting of the lever about the first and second directions permits the double-locking function to be performed, so that the electric drive has only to control two movements in order to execute the three functions: locking, child safety and double-locking.