Patents by Inventor Marissa M. Darmoc

Marissa M. Darmoc has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9447169
    Abstract: The invention relates to hemostatic compositions and methods for promoting hemostasis. The invention also relates to hemostatic compositions and methods for promoting wound healing. In various embodiments, the hemostatic compositions comprise crosslinkable collagen molecules having a porosity controlled by the ratio of weight percent collagen solids to weight percent crosslinker when crosslinking the collagen. In other embodiments, the hemostatic compositions comprise crosslinkable collagen molecules having a porosity controlled by the temperature and rate of freezing when drying the composition during fabrication. In some embodiments, the compositions contain additional agents, including biological agents.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: September 20, 2016
    Assignee: Orthovita, Inc.
    Inventors: Marissa M. Darmoc, Lauren S. Brown, Jenny E. Raynor, Alice Chou, Abigail Cohen
  • Publication number: 20150133578
    Abstract: Methods of preparing bioactive composites are described. Also described are methods of molding such composites. Shaped bodies comprising bioactive composites are further described.
    Type: Application
    Filed: January 26, 2015
    Publication date: May 14, 2015
    Inventors: James P. Murphy, Erik M. Erbe, Charanpreet S. Bagga, Marissa M. Darmoc
  • Patent number: 8968797
    Abstract: Methods of preparing bioactive composites are described. Also described are methods of molding such composites. Shaped bodies comprising bioactive composites are further described.
    Type: Grant
    Filed: September 25, 2007
    Date of Patent: March 3, 2015
    Assignee: Orthovita, Inc.
    Inventors: James P. Murphy, Erik M. Erbe, Charanpreet S. Bagga, Marissa M. Darmoc
  • Patent number: 8778378
    Abstract: The present invention generally relates to bioactive antibacterial materials and composites that enhance bone growth while preventing surgical site infection. The present invention also relates to bioactive antibacterial materials and composites that include a bimodal bioactive glass particle size distribution. The bioactive antibacterial composite finds utility in a variety of clinical applications including spine and orthopaedic procedures.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: July 15, 2014
    Assignee: Orthovita, Inc.
    Inventors: Theodore D. Clineff, Marissa M. Darmoc, Lauren Brown
  • Patent number: 8647614
    Abstract: A method for reducing the occurrence of new post-operative fractures in vertebrae of a patient's spine after a vertebroplasty procedure performed to stabilize a fracture in a vertebra of a patient comprising the steps of performing a vertebroplasty procedure to stabilize a fracture in a vertebra of the patient, wherein the vertebroplasty procedure comprises the step of injecting a material into the fractured vertebra, wherein the material is formed by mixing together a first paste and a second paste, wherein the first paste comprises at least one of a polymerizable monomer and a filler, and wherein the second paste comprises at least one of a polymerizable monomer and a filler.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: February 11, 2014
    Assignee: Orthovita, Inc.
    Inventors: Theodore D. Clineff, Maarten Persenaire, Gina M. Nagvajara, Marissa M. Darmoc, Matthew B. Havener, Stephen G. Gilbert, Erik M. Erbe
  • Patent number: 8597675
    Abstract: Methods of preparing bioactive composites are described. Also described are methods of molding such composites. Shaped bodies comprising bioactive composites are further described.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: December 3, 2013
    Assignee: Orthovita, Inc.
    Inventors: James P. Murphy, Erik M. Erbe, Charanpreet S. Bagga, Marissa M. Darmoc
  • Patent number: 8460686
    Abstract: The invention relates to biocompatible bone graft materials for repairing bone defects and the application of such bone grafts. The devices of the invention comprise resorbable calcium phosphate, resorbable collagen and bioactive glasses.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: June 11, 2013
    Assignee: Orthovita, Inc.
    Inventors: Theodore D. Clineff, Antony Koblish, Charanpreet S. Bagga, Erik M. Erbe, Gina M. Nagvajara, Marissa M. Darmoc
  • Patent number: 8303967
    Abstract: The invention relates to biocompatible bone graft materials for repairing bone defects and the application of such bone grafts. The devices of the invention comprise resorbable calcium phosphate, resorbable collagen, and bioactive glasses.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: November 6, 2012
    Assignee: Orthovita, Inc.
    Inventors: Theodore D. Clineff, Antony Koblish, Charanpreet S. Bagga, Erik M. Erbe, Gina M. Nagvajara, Marissa M. Darmoc
  • Publication number: 20120237568
    Abstract: Methods of preparing bioactive composites are described. Also described are methods of molding such composites. Shaped bodies comprising bioactive composites are further described.
    Type: Application
    Filed: March 21, 2012
    Publication date: September 20, 2012
    Inventors: James P. Murphy, Erik M. Erbe, Charanpreet S. Bagga, Marissa M. Darmoc
  • Publication number: 20120230977
    Abstract: The invention relates to hemostatic compositions and methods for promoting hemostasis. The invention also relates to hemostatic compositions and methods for promoting wound healing. In various embodiments, the hemostatic compositions comprise crosslinkable collagen molecules having a porosity controlled by the ratio of weight percent collagen solids to weight percent crosslinker when crosslinking the collagen. In other embodiments, the hemostatic compositions comprise crosslinkable collagen molecules having a porosity controlled by the temperature and rate of freezing when drying the composition during fabrication. In some embodiments, the compositions contain additional agents, including biological agents.
    Type: Application
    Filed: March 2, 2012
    Publication date: September 13, 2012
    Inventors: Marissa M. Darmoc, Lauren S. BROWN, Jenny E. RAYNOR, Alice CHOU, Abigail COHEN
  • Publication number: 20110151027
    Abstract: The present invention is directed to strontium-containing calcium phosphate bone graft materials. Methods of making and using the bone grafts are also described.
    Type: Application
    Filed: December 21, 2009
    Publication date: June 23, 2011
    Inventors: Theodore D Clineff, Justin J. Martin, Matthew B. Havener, Marissa M. Darmoc
  • Publication number: 20110150963
    Abstract: The present invention generally relates to bioactive antibacterial materials and composites that enhance bone growth while preventing surgical site infection. The present invention also relates to bioactive antibacterial materials and composites that include a bimodal bioactive glass particle size distribution. The bioactive antibacterial composite finds utility in a variety of clinical applications including spine and orthopaedic procedures.
    Type: Application
    Filed: December 21, 2009
    Publication date: June 23, 2011
    Inventors: Theodore D. Clineff, Marissa M. Darmoc, Lauren Brown
  • Publication number: 20100247478
    Abstract: A method for reducing the occurrence of new post-operative fractures in vertebrae of a patient's spine after a vertebroplasty procedure performed to stabilize a fracture in a vertebra of a patient comprising the steps of performing a vertebroplasty procedure to stabilize a fracture in a vertebra of the patient, wherein the vertebroplasty procedure comprises the step of injecting a material into the fractured vertebra, wherein the material is formed by mixing together a first paste and a second paste, wherein the first paste comprises at least one of a polymerizable monomer and a filler, and wherein the second paste comprises at least one of a polymerizable monomer and a filler.
    Type: Application
    Filed: February 16, 2010
    Publication date: September 30, 2010
    Inventors: Theodore D. Clineff, Maarten Persenaire, Gina M. Nagvajara, Marissa M. Darmoc, Matthew B. Havener, Stephen G. Gilbert, Erik M. Erbe
  • Publication number: 20100168798
    Abstract: The present invention generally relates to bioactive composites of polymer and glass and, more particularly, to bioactive implants. The present invention also relates to methods of manufacturing bioactive composites. The bioactive composite finds utility in a variety of load-bearing clinical applications including spine, orthopaedic and dental procedures.
    Type: Application
    Filed: October 13, 2009
    Publication date: July 1, 2010
    Inventors: Theodore D. Clineff, Marissa M. Darmoc, Matthew B. Havener, James P. Murphy, Zachary S. Szczerbinski
  • Publication number: 20100129416
    Abstract: Methods of preparing bioactive composites are described. Also described are methods of molding such composites. Shaped bodies comprising bioactive composites are further described.
    Type: Application
    Filed: September 25, 2007
    Publication date: May 27, 2010
    Applicant: ORTHOVITA, INC
    Inventors: James P. Murphy, Erik M. Erbe, Charanpreet S. Bagga, Marissa M. Darmoc
  • Publication number: 20080187571
    Abstract: The invention relates to biocompatible bone graft materials for repairing bone defects and the application of such bone graft materials.
    Type: Application
    Filed: June 29, 2007
    Publication date: August 7, 2008
    Applicant: Orthovita, Inc.
    Inventors: Theodore D. Clineff, Antony Koblish, Charanpreet S. Bagga, Erik M. Erbe, Gina M. Nagvajara, Marissa M. Darmoc