Patents by Inventor Mark L. Mathis

Mark L. Mathis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150057695
    Abstract: The invention provides improved medical devices, therapeutic treatment systems, and treatment methods for treatment of the lung. A lung volume reduction system includes an implantable device having an elongate body that is sized and shaped for delivery via the airway system to a lung airway of a patient. The implant is inserted and positioned while the implant is in a delivery configuration, and is reconfigured to a deployed configuration so as to locally compress adjacent tissue of the lung, with portions of the elongate body generally moving laterally within the airway so as to laterally compress lung tissue. A plurality of such implants will often be used to treat a lung of a patient.
    Type: Application
    Filed: April 24, 2014
    Publication date: February 26, 2015
    Applicant: PneumRx, Inc.
    Inventors: Mark L. Mathis, David Thompson, Nathan Aronson, Patrick Wu
  • Publication number: 20150051709
    Abstract: A device for enhancing the breathing efficiency of a patient is provided. The implantable device may include a deployed configuration with one or more helical sections with proximal end in a stand-off proximal end configuration. The stand-off proximal end configuration may reduce migration of the deployed device and may preserve implant tissue compression. Alternative configurations may include two or more helical sections with a transition section disposed between the two or more helical sections. A device may include a right-handed helical section and a left-handed helical section and the transition section comprises a switchback transition section. The switchback section may provide greater control of the device during deployment by limiting recoiling forces of a device comprising a spring material. The deployed device may compress the lung to increase a gas filling resistance of the compressed portion of the lung, and/or increase tension and elastic recoil in other portions of the lung.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 19, 2015
    Applicant: PneumRx, Inc.
    Inventors: Jaime Vasquez, Mark L. Mathis, Tim Machold, Andrew Stein
  • Patent number: 8932310
    Abstract: A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: January 13, 2015
    Assignee: PneumRx, Inc.
    Inventors: David Thompson, Nathan Aronson, Patrick Wu, David Lehrberg, Mark L. Mathis, Michael Boutillette, Jaime Vasquez
  • Publication number: 20140371705
    Abstract: A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.
    Type: Application
    Filed: January 23, 2014
    Publication date: December 18, 2014
    Applicant: PneumRx, Inc.
    Inventors: David Thompson, Nathan Aronson, Patrick Wu, David Lehrberg, Mark L. Mathis, Michael Boutillette, Jaime Vasquez
  • Patent number: 8888800
    Abstract: The invention provides improved medical devices, therapeutic treatment systems, and treatment methods for treatment of the lung. A lung volume reduction system includes an implantable device having an elongate body that is sized and shaped for delivery via the airway system to a lung airway of a patient. The implant is inserted and positioned while the implant is in a delivery configuration, and is reconfigured to a deployed configuration so as to locally compress adjacent tissue of the lung, with portions of the elongate body generally moving laterally within the airway so as to laterally compress lung tissue. A plurality of such implants will often be used to treat a lung of a patient.
    Type: Grant
    Filed: March 13, 2012
    Date of Patent: November 18, 2014
    Assignee: PneumRx, Inc.
    Inventors: Mark L. Mathis, David Thompson, Nathan Aronson, Patrick Wu
  • Publication number: 20140236219
    Abstract: A vessel-occluding medical device for the use in diagnosis and/or treatment of cardiovascular disease in the human body includes an outer tube, an inner tube slidably housed within the outer tube, and a tubular sleeve comprising a generally U-shaped, direction reversing region, which moves along the length of the tubular sleeve, to assume radially contracted and radially expanded state as the inner and outer tubes move between the first and second positions. When the tubular sleeve is in the radially expanded state, the inner portion of the tubular sleeve has a funnel-shaped surface and a longitudinally-extending opening to permit material to pass therethrough for receipt of material into the inner tube.
    Type: Application
    Filed: April 30, 2014
    Publication date: August 21, 2014
    Applicant: Capture Vascular, Inc.
    Inventors: William R. DUBRUL, Brent D. SEYBOLD, Mark L. MATHIS, Phillip M. LEOPOLD, Richard E. FULTON, III
  • Publication number: 20140188246
    Abstract: A lung volume reduction system is disclosed comprising an elongate implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to compress lung tissue. The implant may be longer in axial length than an axial length of the target axial region in which it is deployed. Deployment may involve allowing an end of the implant to move relative to surrounding tissue while the implant is progressively deployed.
    Type: Application
    Filed: December 19, 2013
    Publication date: July 3, 2014
    Applicant: PneumRx, Inc.
    Inventors: Nathan Aronson, Mark L. Mathis
  • Publication number: 20140188127
    Abstract: A vessel-occluding medical device for the use in diagnosis and/or treatment of cardiovascular disease in the human body includes an outer tube, an inner tube slidably housed within the outer tube, and a tubular sleeve comprising a generally U-shaped, direction reversing region, which moves along the length of the tubular sleeve, to assume radially contracted and radially expanded state as the inner and outer tubes move between the first and second positions. When the tubular sleeve is in the radially expanded state, the inner portion of the tubular sleeve has a funnel-shaped surface and a longitudinally-extending opening to permit material to pass therethrough for receipt of material into the inner tube.
    Type: Application
    Filed: March 7, 2014
    Publication date: July 3, 2014
    Inventors: William R. DUBRUL, Brent D. SEYBOLD, Mark L. MATHIS, Phillip M. LEOPOLD, Richard E. FULTON, III
  • Patent number: 8740921
    Abstract: The invention provides improved medical devices, therapeutic treatment systems, and treatment methods for treatment of the lung. A lung volume reduction system includes an implantable device having an elongate body that is sized and shaped for delivery via the airway system to a lung airway of a patient. The implant is inserted and positioned while the implant is in a delivery configuration, and is reconfigured to a deployed configuration so as to locally compress adjacent tissue of the lung, with portions of the elongate body generally moving laterally within the airway so as to laterally compress lung tissue. A plurality of such implants will often be used to treat a lung of a patient.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: June 3, 2014
    Assignee: PneumRx, Inc.
    Inventors: Mark L. Mathis, David Thompson, Nathan Aronson, Patrick Wu
  • Patent number: 8721734
    Abstract: Elongate implant structures can be introduced into an airway system to a target airway axial region, often to apply lateral bending and/or compression forces against the lung tissue from within the airways for an extended period of time. Structures or features of the implants may inhibit tissue reactions that might otherwise allow portions of the device to eventually traverse through the wall of the airway. The devices may enhance the area bearing laterally on the tissue of a surrounding airway lumen wall. Embodiments may have features which increase the device friction with the airway to allow the device to grip the surrounding airway as the device is deployed. An appropriate adhesive may be introduced around the device in the lung. Hydrophilic material may inhibit biofilm formation, or features which induce some tissue ingrowth (stimulation of tissue growth) may enhance implanted device supported.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: May 13, 2014
    Assignee: PneumRx, Inc.
    Inventors: Mark L. Mathis, Patrick Wu, David Lehrberg, Jaime Vasquez, Erin McGurk, Ronald Dieck, Andrew Stein
  • Patent number: 8668707
    Abstract: A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: March 11, 2014
    Assignee: PneumRx, Inc.
    Inventors: David Thompson, Nathan Aronson, Patrick Wu, David Lehrberg, Mark L. Mathis, Michael Boutillette, Jaime Vasquez
  • Patent number: 8632605
    Abstract: A lung volume reduction system is disclosed comprising an elongate implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to compress lung tissue. The implant may be longer in axial length than an axial length of the target axial region in which it is deployed. Deployment may involve allowing an end of the implant to move relative to surrounding tissue while the implant is progressively deployed.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: January 21, 2014
    Assignee: PneumRx, Inc.
    Inventors: David Thompson, Nathan Aronson, Patrick Wu, David Lehrberg, Mark L. Mathis, Michael Boutillette, Jaime Vasquez
  • Publication number: 20130253629
    Abstract: The present invention provides devices and methods for use in the perfusion of organs and anatomical regions. In one aspect the present method provides a percutaneously deliverable device for supporting a vessel in a human or animal subject including means for supporting the vessel during delivery of a fluid thereto or collection of a fluid therefrom. In another aspect the invention provides a method for delivery or collection of a fluid to or from an organ or anatomical region in a human or animal subject, the method including the step of supporting a vessel associated with the organ or anatomical region. The devices and methods may be used to deliver, remove or recirculate a therapeutic agent to an organ or anatomical region.
    Type: Application
    Filed: May 13, 2013
    Publication date: September 26, 2013
    Applicant: Osprey Medical Inc.
    Inventors: John Melmouth Power, Mark L. Mathis, David Martin Kaye, Adam Lucas Bilney
  • Publication number: 20130217956
    Abstract: A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.
    Type: Application
    Filed: September 14, 2012
    Publication date: August 22, 2013
    Applicant: PneumRx, Inc.
    Inventors: David Thompson, Nathan Aronson, Patrick Wu, David Lehrberg, Mark L. Mathis, Michael Boutillette, Jaime Vasquez
  • Publication number: 20130110152
    Abstract: A vessel-occluding medical device for the use in diagnosis and/or treatment of cardiovascular disease in the human body includes an outer tube, an inner tube slidably housed within the outer tube, and a tubular sleeve comprising a generally U-shaped, direction reversing region, which moves along the length of the tubular sleeve, to assume radially contracted and radially expanded state as the inner and outer tubes move between the first and second positions. When the tubular sleeve is in the radially expanded state, the inner portion of the tubular sleeve has a funnel-shaped surface and a longitudinally-extending opening to permit material to pass therethrough for receipt of material into the inner tube.
    Type: Application
    Filed: December 21, 2012
    Publication date: May 2, 2013
    Applicant: Genessis Technologies LLC
    Inventors: William R. Dubrul, Brent D. Seybold, Mark L. Mathis, Phillip M. Leopold, Richard E. Fulton, III
  • Publication number: 20130102887
    Abstract: A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.
    Type: Application
    Filed: September 14, 2012
    Publication date: April 25, 2013
    Applicant: PneumRx, Inc.
    Inventors: David Thompson, Nathan Aronson, Patrick Wu, David Lehrberg, Mark L. Mathis, Michael Boutillette, Jaime Vasquez
  • Publication number: 20130103059
    Abstract: A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.
    Type: Application
    Filed: September 14, 2012
    Publication date: April 25, 2013
    Applicant: PneumRx, Inc.
    Inventors: Mark L. Mathis, David Thompson, Patrick Wu
  • Publication number: 20130096603
    Abstract: The invention provides improved medical devices, therapeutic treatment systems, and treatment methods for treatment of the lung. A lung volume reduction system includes an implantable device having an elongate body that is sized and shaped for delivery via the airway system to a lung airway of a patient. The implant is inserted and positioned while the implant is in a delivery configuration, and is reconfigured to a deployed configuration so as to locally compress adjacent tissue of the lung, with portions of the elongate body generally moving laterally within the airway so as to laterally compress lung tissue. A plurality of such implants will often be used to treat a lung of a patient.
    Type: Application
    Filed: September 14, 2012
    Publication date: April 18, 2013
    Applicant: PneumRx, Inc.
    Inventors: Mark L. Mathis, David Thompson, Nathan Aronson, Patrick Wu
  • Patent number: 8282660
    Abstract: A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: October 9, 2012
    Assignee: PneumRx, Inc.
    Inventors: David Thompson, Nathan Aronson, Patrick Wu, David Lehrberg, Mark L. Mathis, Michael Boutillette, Jaime Vasquez
  • Publication number: 20120197389
    Abstract: An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.
    Type: Application
    Filed: April 10, 2012
    Publication date: August 2, 2012
    Inventors: Clifton A. Alferness, John M. Adams, Mark L. Mathis, David G. Reuter, Cruz Beeson, Leonard Kowalsky