Patents by Inventor Martin Anibal Orecchia

Martin Anibal Orecchia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biopharmaceutical compositions comprising antibody variants
    Patent number: 11613571
    Abstract: The present disclosure relates to compositions comprising antibody variants, for treating interleukin 5 (IL-5) mediated diseases, and related methods.
    Type: Grant
    Filed: May 21, 2019
    Date of Patent: March 28, 2023
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Chika Akinseye, Tejinder Bhinder, Li Cui, Steven Grant, Laura Hook, Alan Peter Lewis, Martin Anibal Orecchia
  • BIOPHARMACEUTICAL COMPOSITIONS COMPRISING ANTIBODY VARIANTS
    Publication number: 20210115128
    Abstract: The present disclosure relates to compositions comprising antibody variants, for treating interleukin 5 (IL-5) mediated diseases, and related methods.
    Type: Application
    Filed: May 21, 2019
    Publication date: April 22, 2021
    Inventors: Chika AKINSEYE, Tejinder BHINDER, Li CUI, Steven GRANT, Laura HOOK, Alan Peter LEWIS, Martin Anibal ORECCHIA
  • ANTIGEN-BINDING CONSTRUCTS
    Publication number: 20160207993
    Abstract: The invention relates to antigen-binding constructs comprising a protein scaffold which are linked to one or more epitope-binding domains wherein the antigen-binding construct has at least two antigen binding sites at least one of which is from an epitope binding domain and at least one of which is from a paired VH/VL domain, methods of making such constructs and uses thereof.
    Type: Application
    Filed: June 15, 2015
    Publication date: July 21, 2016
    Inventors: Claire ASHMAN, Thil Batuwangala, Michael Neil Burden, Stephanie Jane Clegg, Rudolf Maria De Wildt, Jonathan Henry Ellis, Paul Andrew Hamblin, Farhana Hussain, Laurent Jespers, Alan Lewis, Martin Anibal Orecchia, Radha Shah, Michael Steward
  • Antigen-binding proteins
    Patent number: 9394374
    Abstract: The invention relates to linkers suitable for use in antigen-binding proteins, certain antigen binding proteins and methods of making such proteins and uses thereof.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: July 19, 2016
    Assignee: Glaxo Group Limited
    Inventors: Paul Andrew Hamblin, Alan Peter Lewis, Martin Anibal Orecchia, Radha Shah Parmar
  • IL-13 binding protein
    Patent number: 8680245
    Abstract: The present invention relates to antigen binding proteins to human IL-13, including anti-IL-13 antibodies and anti-IL-3/anti-IL-4 mAbdAbs, pharmaceutical formulations containing them and to the use of such antigen binding proteins in the treatment and/or prophylaxis of inflammatory diseases such as asthma or IPF.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: March 25, 2014
    Assignee: Glaxo Group Limited
    Inventors: Claire Ashman, Jonathan Henry Ellis, Paul Andrew Hamblin, Alan Peter Lewis, Martin Anibal Orecchia
  • HUMANISED ANTIGEN BINDING PROTEINS TO MYOSTATIN6
    Publication number: 20130142788
    Abstract: The present invention relates to humanised antigen binding proteins, such as antibodies, which bind to myostatin, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. The present invention also concerns the use of such humanised antigen binding proteins in the treatment or prophylaxis of diseases associated with any one or a combination of decreased muscle mass, muscle strength and muscle function.
    Type: Application
    Filed: June 2, 2011
    Publication date: June 6, 2013
    Inventors: Claire Ashman, Stephen Ashman, Paul Andrew Hamblin, Alan Peter Lewis, Martin Anibal Orecchia
  • IL-13 BINDING PROTEIN
    Publication number: 20120082682
    Abstract: The present invention relates to antigen binding proteins to human IL-13, including anti-IL-13 antibodies and anti-IL-3/anti-IL-4 mAbdAbs, pharmaceutical formulations containing them and to the use of such antigen binding proteins in the treatment and/or prophylaxis of inflammatory diseases such as asthma or IPF.
    Type: Application
    Filed: May 26, 2010
    Publication date: April 5, 2012
    Inventors: Claire Ashman, Jonathan Henry Ellis, Paul Andrew Hamblin, Alan Peter Lewis, Martin Anibal Orecchia
  • ANTIGEN-BINDING PROTEINS
    Publication number: 20120070439
    Abstract: The invention relates to linkers suitable for use in antigen-binding proteins, certain antigen binding proteins and methods of making such proteins and uses thereof.
    Type: Application
    Filed: May 26, 2010
    Publication date: March 22, 2012
    Inventors: Paul Andrew Hamblin, Alan Peter Lewis, Martin Anibal Orecchia, Radha Shah Parmar
  • MYOSTATIN BINDING PROTEINS
    Publication number: 20110256132
    Abstract: Description of antigen binding proteins, such as antibodies, which bind to myostatin, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. Furthermore, description of the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with anyone or a combination of decreased muscle mass, muscle strength and muscle function.
    Type: Application
    Filed: December 18, 2009
    Publication date: October 20, 2011
    Inventors: Claire Ashman, Andrew Beaton, Jonathan Henry Ellis, Baijin Han, Ian Kirby, Frederick Kull, Alan Lewis, Kathryn Mason Lindley, Martin Anibal Orecchia, Ying Shen, Paul Wilson, Tian Shun Xun, Hong Zhang
  • ANTIGEN-BINDING CONSTRUCTS
    Publication number: 20110008345
    Abstract: The invention relates to antigen-binding constructs comprising a protein scaffold which are linked to one or more epitope-binding domains wherein the antigen-binding construct has at least two antigen binding sites at least one of which is from an epitope binding domain and at least one of which is from a paired VH/VL domain, methods of making such constructs and uses thereof.
    Type: Application
    Filed: November 28, 2008
    Publication date: January 13, 2011
    Inventors: Claire Ashman, Thil Batuwangala, Michael Neil Burden, Stephanie Jane Clegg, Rudolf Maria De Wildt, Jonathan Henry Ellis, Paul Andrew Hamblin, Farhana Hussain, Laurent Jespers, Alan Lewis, Martin Anibal Orecchia, Radha Shah, Michael Steward
  • IMMUNOGLOBULINS
    Publication number: 20100303821
    Abstract: The present invention relates to antigen binding proteins to human IL-13, including anti-IL-13 antibodies and anti-IL-3/anti-IL-4 mAbdAbs, pharmaceutical formulations containing them and to the use of such antigen binding proteins in the treatment and/or prophylaxis of inflammatory diseases such as asthma or IPF.
    Type: Application
    Filed: May 26, 2010
    Publication date: December 2, 2010
    Applicant: GLAXO GROUP LIMITED
    Inventors: CLAIRE ASHMAN, JONATHAN HENRY ELLIS, PAUL ANDREW HAMBLIN, ALAN PETER LEWIS, MARTIN ANIBAL ORECCHIA
  • ANTIGEN-BINDING CONSTRUCTS
    Publication number: 20090148905
    Abstract: The invention relates to antigen-binding constructs comprising a protein scaffold which are linked to one or more epitope-binding domains wherein the antigen-binding construct has at least two antigen binding sites at least one of which is from an epitope binding domain and at least one of which is from a paired VH/VL domain, methods of making such constructs and uses thereof.
    Type: Application
    Filed: November 28, 2008
    Publication date: June 11, 2009
    Inventors: Claire ASHMAN, Thil Batuwangala, Michael Neil Burden, Stephanie Jane Clegg, Rudolf Maria De Wildt, Jonathan Henry Ellis, Paul Andrew Hamblin, Farhana Hussain, Laurent Jespers, Alan Lewis, Martin Anibal Orecchia, Radha Shah, Michael Steward