Patents by Inventor Martin T. Gerber

Martin T. Gerber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190224399
    Abstract: The invention relates to devices, systems, and methods for recharging zirconium phosphate. The devices, system, and methods use a patient pre-dialysis BUN level to set one or more recharge parameters for recharging the zirconium phosphate. The devices, systems, and methods allow for precision recharging of the zirconium phosphate based on the patient pre-dialysis BUN level.
    Type: Application
    Filed: March 29, 2019
    Publication date: July 25, 2019
    Inventors: Kenneth J. Collier, Christopher M. Hobot, Martin T. Gerber, Bryant J. Pudil
  • Patent number: 10357757
    Abstract: A stacked sorbent assembly for use in sorbent dialysis. The stacked sorbent assembly contains two or more interchangeable sorbent pouches that allow for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouches. Any of the pouches in the sorbent cartridge can be reused and/or recharged.
    Type: Grant
    Filed: March 11, 2015
    Date of Patent: July 23, 2019
    Assignee: MEDTRONIC, INC.
    Inventors: Martin T. Gerber, Christopher M. Hobot
  • Patent number: 10343145
    Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer or module of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include a fluid source containing at least one recharging fluid, wherein the fluid source is fluidly connectable to at least one rechargeable sorbent module for use in sorbent dialysis in a fluid flow path. The methods and apparatuses include passing a single solution through the zirconium phosphate for ion exchanges, resulting in zirconium phosphate to maintain a substantially consistent pH in a dialysate used during dialysis.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: July 9, 2019
    Assignee: Medtronic, Inc.
    Inventors: Bryant J. Pudil, Martin T. Gerber, Christopher M. Hobot
  • Publication number: 20190201810
    Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis. The system is configured to allow insertion of a urease pouch, injection of a urease solution, or addition of a urease cartridge, into a dialysis cabinet containing a dialysis flow loop. The urease can be dissolved and the resulting urease solution added to the sorbent cartridge in the flow loop to replenish the urease within the sorbent cartridge. The sorbent cartridge can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.
    Type: Application
    Filed: March 14, 2019
    Publication date: July 4, 2019
    Inventors: Martin T. Gerber, Christopher M. Hobot
  • Patent number: 10335534
    Abstract: Systems and methods are provided for determining an estimated risk of arrhythmia during or after dialysis based on changes in serum potassium concentration of a patient and an amount of fluid removed from the patient during dialysis. The systems and methods allow for a determination of a risk that arrhythmia will occur due to the changes in potassium and fluid volume of a patient during dialysis, and for optimizing a dialysis prescription in order to minimize the risk of arrhythmia.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: July 2, 2019
    Assignee: Medtronic, Inc.
    Inventors: Amy Roettger, VenKatesh R. Manda, John Burnes, Rebecca Poindexter, Martin T. Gerber
  • Patent number: 10286380
    Abstract: A sorbent pouch for use in sorbent dialysis. The sorbent pouch allows for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouch.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: May 14, 2019
    Assignee: Medtronic, Inc.
    Inventors: Martin T. Gerber, Christopher M. Hobot
  • Publication number: 20190134288
    Abstract: A medical monitoring device for monitoring electrical signals from the body of a subject is described. The medical monitoring device monitors electrical signals originating from a cardiac cycle of the subject and associates each cardiac cycle with a time index. The medical monitoring device applies a forward computational procedure to generate a risk score indicative of hyperkalemia, hypokalemia or arrhythmia of the subject. The medical monitoring device can adjust the forward computational procedure based upon clinical data obtained from the subject.
    Type: Application
    Filed: January 7, 2019
    Publication date: May 9, 2019
    Inventors: Orhan Soykan, VenKatesh R. Manda, Martin T. Gerber, Christopher M. Hobot
  • Publication number: 20190134291
    Abstract: The invention relates to systems and methods for estimating a patient urea level at any arbitrary time during dialysis treatment. The systems and methods use either one or more urea sensors or any two of a pH sensor, ammonia sensor, and ammonium sensor to determine an amount of urea removed by a dialysate regeneration system. The systems and methods use the amount of urea removed by the dialysate regeneration system to estimate the patient urea level.
    Type: Application
    Filed: October 1, 2018
    Publication date: May 9, 2019
    Inventors: Michael J. M. Mazack, Martin T. Gerber, Christopher M. Hobot
  • Publication number: 20190134289
    Abstract: The invention relates to systems and methods for performing dialysis with closed-loop control of sodium and bicarbonate concentrations in the dialysate. The system and methods can use one or more conductivity sensors in a dialysate flow path to determine a water addition rate and a bicarbonate addition rate resulting in a dialysate having desired sodium and bicarbonate concentrations.
    Type: Application
    Filed: October 1, 2018
    Publication date: May 9, 2019
    Inventors: Bryant J. Pudil, Martin T. Gerber, Christopher M. Hobot
  • Patent number: 10272363
    Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis. The system is configured to allow insertion of a urease pouch, injection of a urease solution, or addition of a urease cartridge, into a dialysis cabinet containing a dialysis flow loop. The urease can be dissolved and the resulting urease solution added to the sorbent cartridge in the flow loop to replenish the urease within the sorbent cartridge. The sorbent cartridge can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.
    Type: Grant
    Filed: March 9, 2015
    Date of Patent: April 30, 2019
    Assignee: MEDTRONIC, INC.
    Inventors: Martin T. Gerber, Christopher M. Hobot
  • Patent number: 10258728
    Abstract: Systems and methods are provided for performing selective sorbent-based regeneration of dialysate. The systems and method provide for dialysate regeneration to be carried out intermittently throughout a dialysis session, decreasing the necessary amounts of sorbent materials and infusates to conduct dialysis. The system and methods allow for regeneration of dialysate as needed based on the concentration of waste species in the dialysate, allowing for effective treatment with a decreased need for sorbent materials.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: April 16, 2019
    Assignee: Medtronic, Inc.
    Inventor: Martin T. Gerber
  • Publication number: 20190099538
    Abstract: A customizable modular dialysate regeneration assembly with connectable sorbent packaging systems. The dialysate regeneration assembly can be customized based on patient parameters or dialysis session parameters. A processor can be included that can determine the correct amount of each sorbent material necessary for a given patient and a given dialysis session.
    Type: Application
    Filed: December 3, 2018
    Publication date: April 4, 2019
    Inventors: Martin T. Gerber, Christopher M. Hobot
  • Patent number: 10245365
    Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis. The sorbent cartridge is configured to allow an amount of urease to be added to the sorbent cartridge. A urease solution can be injected into the sorbent cartridge to replenish the urease containing module, or solid urease can be added to the sorbent cartridge. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: April 2, 2019
    Assignee: Medtronic, Inc.
    Inventors: Martin T. Gerber, Christopher M. Hobot
  • Publication number: 20190091394
    Abstract: A portable dialysis cabinet for use in dialysis. The portable dialysis cabinet can have a size and weight that facilitates easy movement of the cabinet from one location to another with relative ease. The portable dialysis cabinet can have additional features necessary to facilitate portability, such as wheels and a handle. In general, the portable dialysis cabinet can contain all the necessary components for performing a dialysis session.
    Type: Application
    Filed: November 28, 2018
    Publication date: March 28, 2019
    Inventors: Thomas E. Meyer, David B. Lura, Bryant J. Pudil, Martin T. Gerber
  • Patent number: 10207041
    Abstract: A medical monitoring device for monitoring electrical signals from the body of a subject is described. The medical monitoring device monitors electrical signals originating from a cardiac cycle of the subject and associates each cardiac cycle with a time index. The medical monitoring device applies a forward computational procedure to generate a risk score indicative of hyperkalemia, hypokalemia or arrhythmia of the subject. The medical monitoring device can adjust the forward computational procedure based upon clinical data obtained from the subject.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: February 19, 2019
    Assignee: Medtronic, Inc.
    Inventors: Orhan Soykan, VenKatesh R. Manda, Martin T. Gerber, Christopher M. Hobot
  • Publication number: 20190038997
    Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis using urease pouches. The sorbent cartridge is configured to allow insertion of a urease pouch or injection of a urease solution into the sorbent cartridge containing a urease pouch. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.
    Type: Application
    Filed: October 9, 2018
    Publication date: February 7, 2019
    Inventors: Martin T. Gerber, Christopher M. Hobot
  • Publication number: 20190038824
    Abstract: A blood based solute monitoring system for measuring at least one blood solute species that has a first recirculation flow path in fluid communication with a dialyzer. The first recirculation flow path is configured to allow a fluid to recirculate through a dialyzer such that the concentration of at least one solute species in the fluid becomes equilibrated to the solute species concentration of the blood in a blood compartment of the dialyzer. The blood solute monitoring system has at least one sensor to measure a fluid characteristic.
    Type: Application
    Filed: October 9, 2018
    Publication date: February 7, 2019
    Inventors: Bryant J. Pudil, Thomas E. Meyer, David B. Lura, Martin T. Gerber
  • Patent number: 10172991
    Abstract: A customizable modular dialysate regeneration assembly with connectable sorbent packaging systems. The dialysate regeneration assembly can be customized based on patient parameters or dialysis session parameters. A processor can be included that can determine the correct amount of each sorbent material necessary for a given patient and a given dialysis session.
    Type: Grant
    Filed: March 11, 2015
    Date of Patent: January 8, 2019
    Assignee: Medtronic, Inc.
    Inventors: Martin T. Gerber, Christopher M. Hobot
  • Publication number: 20190001303
    Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer or module of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include a fluid source containing at least one recharging fluid, wherein the fluid source is fluidly connectable to at least one rechargeable sorbent module for use in sorbent dialysis in a fluid flow path. The methods and apparatuses include passing a single solution through the zirconium phosphate for ion exchanges, resulting in zirconium phosphate to maintain a substantially consistent pH in a dialysate used during dialysis.
    Type: Application
    Filed: July 27, 2018
    Publication date: January 3, 2019
    Inventors: Bryant J. Pudil, Martin T. Gerber, Christopher M. Hobot
  • Publication number: 20180353136
    Abstract: A system and method for determining the amount of fluid to be removed from a dialysis patient is disclosed. The system utilizes sensors and a computer. The computer obtains the input parameters from the sensors, along with information added directly by the user, and performs a forward algorithm to determine a recommended change in patient fluid level. As fluid is removed, the effect of the removal on the parameters is detected by the sensors and re-transmitted back to the computer. The computer then performs a backward algorithm to refine the variables used in the forward algorithm and obtain more accurate results. The system and method provide for changing the amount of fluid removed from the patient based on the results of the algorithm and the data received from the sensors.
    Type: Application
    Filed: August 21, 2018
    Publication date: December 13, 2018
    Inventors: Orhan SOYKAN, Christopher M. HOBOT, Martin T. GERBER, VenKatesh R. MANDA