Patents by Inventor Mary L. Nicholson

Mary L. Nicholson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibodies specific for 330 KD breast tumor antigen and assay using said monoclonal antibodies
    Patent number: 4960716
    Abstract: A substantially pure antigen found on normal and benign breast epithelial cell membranes and in breast cancer cells, fused cell hybrids which produce antibodies specific for such antigen, the monoclonal antibodies produced by such fused cell hybrids, a method for detecting the presence of breast cancer in a patient which is based on measuring the concentrations of one or more determinants of such antigen in a patient sample, and a method for either identifying those breast cancer patients whose tumors would respond to estrogen manipulation or determining prognosis based on the degree of differentiation, which method is based on measuring the concentration of an estrogen-modulated determinant of such antigen.
    Type: Grant
    Filed: December 28, 1988
    Date of Patent: October 2, 1990
    Assignee: Ciba Corning Diagnostics Corp.
    Inventors: Michael A. Harvey, Brenda D. Manning, Mary L. Nicholson, Karen L. Travis, Albert A. Luderer