Patents by Inventor Mary Maral Mouradian

Mary Maral Mouradian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating dyskinesia
    Patent number: 9289423
    Abstract: Methods of treating patients with dyskinesias, by administering a therapeutically effective amount of a dual-action mu-opioid receptor antagonist/kappa-opioid receptor agonist or prodrug thereof to a subject in need thereof, sufficient to mitigate the dyskinesia. Alternatively, a combination of both a mu-opioid receptor antagonist or prodrug thereof, and a kappa-opioid receptor agonist or prodrug thereof can be administered, either together or separately.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: March 22, 2016
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Mary Maral Mouradian, Steven Braithwaite, Michael Voronkov
  • RNA targeting in alpha-synucleinopathies
    Patent number: 9255266
    Abstract: Therapies and assays to screen for small molecules that can have therapeutic use in the control of neurodegenerative diseases such as Parkinson's and other alpha-synucleinopathies.
    Type: Grant
    Filed: May 6, 2010
    Date of Patent: February 9, 2016
    Assignee: Rutgers, the State University of New Jersey
    Inventors: Mary Maral Mouradian, Eunsung Junn
  • RNA Targeting in Alpha-Synucleinopathies
    Publication number: 20120129912
    Abstract: Therapies and assays to screen for small molecules that can have therapeutic use in the control of neurodegenerative diseases such as Parkinson's and other alpha-synucleinopathies.
    Type: Application
    Filed: May 6, 2010
    Publication date: May 24, 2012
    Applicant: University of Medicine and Dentistry of New Jersey
    Inventors: Mary Maral Mouradian, Eunsung Junn
  • Use of marrow-derived glial progenitor cells as gene delivery vehicles into the central nervous system
    Patent number: 7022321
    Abstract: The present disclosure relates to a method for introducing a hematopoietic cell into the brain of a mammal, by administering bone marrow-derived progenitor cells into the body of the mammal by intravenous injection. The bone marrow-derived cell is preferably a cell that differentiates into a glial cell. The disclosure also relates to a method for delivery of therapeutic protein molecules into the brain of a mammal, by administering to a mammal an effective amount of bone marrow-derived progenitor cells which contain a gene having a nucleic acid sequence that encodes a functional therapeutic protein. Isolated recombinant cells and a pharmaceutical composition are also provided.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: April 4, 2006
    Inventors: Martin A. Eglitis, Eva Mezey, Mary Maral Mouradian
  • Use of marrow-derived glial progenitor cells as gene delivery vehicles into the central nervous system
    Publication number: 20030003087
    Abstract: The present disclosure relates to a method for introducing a hematopoietic cell into the brain of a mammal, by administering bone marrow-derived progenitor cells into the body of the mammal by intravenous injection. The bone marrow-derived cell is preferably a cell that differentiates into a glial cell.
    Type: Application
    Filed: April 11, 2002
    Publication date: January 2, 2003
    Applicant: Department of Health and Human Services
    Inventors: Martin A. Eglitis, Eva Mezey, Mary Maral Mouradian