Patents by Inventor Masahiro Ota

Masahiro Ota has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11424086
    Abstract: An operation device includes a housing, an operation member, and a detector. The housing includes an electrically conductive portion on a surface thereof. The operation member is supported by the housing such that the operation member is movable in response to an operation by an operation body, and is configured to be capacitively coupled to the operation body and to the electrically conductive portion. The detector is configured to detect whether the operation body is in proximity to the operation member based on a change in capacitance at the electrically conductive portion.
    Type: Grant
    Filed: February 2, 2021
    Date of Patent: August 23, 2022
    Assignee: ALPS ALPINE CO., LTD.
    Inventors: Yasuji Hagiwara, Daisuke Takai, Takashi Sasaki, Takeshi Masaki, Toshiki Nakamura, Masaki Ota, Hiroshi Shigetaka, Masahiro Takata
  • Patent number: 11254292
    Abstract: A coupling clip includes a clip body that includes a wiper lever anchor portion to be anchored to a coupling shaft provided at a wiper lever assembly supporting a blade rubber, and a wiper arm anchor portion for anchoring a wiper arm. The coupling clip also includes a damper member that is attached to the clip body. When the wiper lever assembly is displaced with respect to the clip body, the damper member is deformed between the wiper lever assembly and the clip body.
    Type: Grant
    Filed: March 19, 2020
    Date of Patent: February 22, 2022
    Assignee: DENSO CORPORATION
    Inventor: Masahiro Ota
  • Publication number: 20220002277
    Abstract: It is intended to provide a novel compound or a salt thereof, or crystals of the compound or the salt, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl. [Solution] The present invention provides a pyridone derivative having a tetrahydropyranylmethyl group represented by the following formula (I) having various substituents, or a salt thereof, or crystals of the compound or the salt (wherein R1, R2, R3, R4, R5, W, X, Y, and Z are each as defined in the specification).
    Type: Application
    Filed: August 12, 2021
    Publication date: January 6, 2022
    Inventors: Noriyasu HAGINOYA, Takashi SUZUKI, Miho HAYAKAWA, Masahiro OTA, Tomoharu TSUKADA, Katsuhiro KOBAYASHI, Yosuke ANDO, Takeshi JIMBO, Koichi NAKAMURA
  • Patent number: 11208403
    Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: December 28, 2021
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Noriyasu Haginoya, Takashi Suzuki, Miho Hayakawa, Masahiro Ota, Tomoharu Tsukada, Katsuhiro Kobayashi, Yosuke Ando, Takeshi Jimbo, Koichi Nakamura
  • Patent number: 11020398
    Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of BTK, a pharmaceutical composition comprising a compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: June 1, 2021
    Assignee: ArQule, Inc.
    Inventors: Craig Bates, Sudharshan Eathiraj, Hiroaki Inagaki, Jean-Marc Lapierre, Takayuki Momose, Kiyoshi Nakayama, Takashi Odagiri, Masahiro Ota, Yusuke Ota, Yoshihiro Shibata, Manish Tandon, Tomoyuki Tsunemi
  • Publication number: 20200353898
    Abstract: A coupling clip includes a clip body that includes a wiper lever anchor portion to be anchored to a coupling shaft provided at a wiper lever assembly supporting a blade rubber, and a wiper arm anchor portion for anchoring a wiper arm. The coupling clip also includes a damper member that is attached to the clip body. When the wiper lever assembly is displaced with respect to the clip body, the damper member is deformed between the wiper lever assembly and the clip body.
    Type: Application
    Filed: March 19, 2020
    Publication date: November 12, 2020
    Applicant: DENSO CORPORATION
    Inventor: Masahiro OTA
  • Patent number: 10774087
    Abstract: Provided is a novel compound or a salt thereof inhibiting MTHFD2 and useful for treating a disease caused by overexpression of MTHFD2, a disease involved in overexpression of MTHFD2 and/or a disease associated with overexpression of MTHFD2. Solution Provided is a sulfonamide derivative having a coumarin skeleton represented by the following formula (I) and having various substituents: wherein R1, R2, R3, R4, R5, R6 and R7 are the same as defined in the specification, and a salt thereof.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: September 15, 2020
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Masahiro Ota, Hidekazu Inoue, Junya Kawai, Hitoshi Ohki, Tadashi Toki
  • Publication number: 20200115446
    Abstract: An object of the present invention is to provide a pharmaceutical agent for the treatment and/or prophylaxis of pediatric osteoporosis without causing bone growth disorder in a subject to be medicated. A pharmaceutical composition for the treatment and/or prophylaxis of pediatric osteoporosis contains an antibody or a functional fragment thereof which binds to Siglec-15 and has activity of suppressing formation of osteoclasts and/or bone resorption by osteoclasts.
    Type: Application
    Filed: June 29, 2018
    Publication date: April 16, 2020
    Applicants: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Masahiko TAKAHATA, Dai SATO, Masahiro OTA, Tomohiro SHIMIZU, Chie FUKUDA, Eisuke TSUDA
  • Publication number: 20200010458
    Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.
    Type: Application
    Filed: September 18, 2019
    Publication date: January 9, 2020
    Inventors: Noriyasu HAGINOYA, Takashi SUZUKI, Miho HAYAKAWA, Masahiro OTA, Tomoharu TSUKADA, Katsuhiro KOBAYASHI, Yosuke ANDO, Takeshi JIMBO, Koichi NAKAMURA
  • Publication number: 20190358233
    Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of BTK, a pharmaceutical composition comprising a compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.
    Type: Application
    Filed: August 5, 2019
    Publication date: November 28, 2019
    Inventors: Craig BATES, Sudharshan Eathiraj, Hiroaki Inagaki, Jean-Marc Lapierre, Takayuki Momose, Kiyoshi Nakayama, Takashi Odagiri, Masahiro Ota, Yusuke Ota, Yoshihiro Shibata, Manish Tandon, Tomoyuki Tsunemi
  • Patent number: 10442797
    Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: October 15, 2019
    Assignee: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Noriyasu Haginoya, Takashi Suzuki, Miho Hayakawa, Masahiro Ota, Tomoharu Tsukada, Katsuhiro Kobayashi, Yosuke Ando, Takeshi Jimbo, Koichi Nakamura
  • Publication number: 20190284198
    Abstract: Provided is a novel compound or a salt thereof inhibiting MTHFD2 and useful for treating a disease caused by overexpression of MTHFD2, a disease involved in overexpression of MTHFD2 and/or a disease associated with overexpression of MTHFD2. Solution Provided is a sulfonamide derivative having a coumarin skeleton represented by the following formula (I) and having various substituents: wherein R1, R2, R3, R4, R5, R6 and R7 are the same as defined in the specification, and a salt thereof.
    Type: Application
    Filed: November 22, 2017
    Publication date: September 19, 2019
    Applicant: Daiichi Sankyo Company, Limited
    Inventors: Masahiro Ota, Hidekazu Inoue, Junya Kawai, Hitoshi Ohki, Tadashi Toki
  • Publication number: 20180148436
    Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.
    Type: Application
    Filed: July 6, 2015
    Publication date: May 31, 2018
    Inventors: Noriyasu HAGINOYA, Takashi SUZUKI, Miho HAYAKAWA, Masahiro OTA, Tomoharu TSUKADA, Katsuhiro KOBAYASHI, Yosuke ANDO, Takeshi JIMBO, Koichi NAKAMURA
  • Publication number: 20180055846
    Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of BTK, a pharmaceutical composition comprising a compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.
    Type: Application
    Filed: August 23, 2017
    Publication date: March 1, 2018
    Inventors: Craig BATES, Sudharshan Eathiraj, Hiroaki Inagaki, Jean-Marc Lapierre, Takayuki Momose, Kiyoshi Nakayama, Takashi Odagiri, Masahiro Ota, Yusuke Ota, Yoshihiro Shibata, Manish Tandon, Tomoyuki Tsunemi
  • Publication number: 20170183329
    Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.
    Type: Application
    Filed: July 6, 2015
    Publication date: June 29, 2017
    Inventors: Noriyasu HAGINOYA, Takashi SUZUKI, Miho HAYAKAWA, Masahiro OTA, Tomoharu TSUKADA, Katsuhiro KOBAYASHI, Yosuke ANDO, Takeshi JIMBO, Koichi NAKAMURA
  • Patent number: 9625178
    Abstract: A water heater attachment method is a method for attaching a water heater body to a wall surface by using an attachment member provided at a rear end of an upper surface of the water heater body. The method includes a first step of inserting a tip of a rod member into a through hole formed in the attachment member, the rod member projecting forward from the wall surface, a second step of sliding the attachment member toward the wall surface along the rod member to shift the water heater body to an attachment position of the wall surface, and a third step of fastening the attachment member to the wall surface by a screw in a state where the attachment member is held by the rod member.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: April 18, 2017
    Assignee: Paloma Co., Ltd.
    Inventors: Masahiro Ota, Ryosuke Umemura
  • Patent number: 9320770
    Abstract: A vascular maturation, normalization or stabilization agent, or a Tie-2 activation agent, is provided comprising an extract derived from a plant belonging to the genus Cinnamomum.
    Type: Grant
    Filed: March 31, 2009
    Date of Patent: April 26, 2016
    Assignee: Shiseido Company, Ltd.
    Inventors: Masahiro Ota, Koji Kobayashi, Ken Kusakari, Makoto Tsunenaga, Nobuyuki Takakura
  • Publication number: 20160033168
    Abstract: A water heater attachment method is a method for attaching a water heater body to a wall surface by using an attachment member provided at a rear end of an upper surface of the water heater body. The method includes a first step of inserting a tip of a rod member into a through hole formed in the attachment member, the rod member projecting forward from the wall surface, a second step of sliding the attachment member toward the wall surface along the rod member to shift the water heater body to an attachment position of the wall surface, and a third step of fastening the attachment member to the wall surface by a screw in a state where the attachment member is held by the rod member.
    Type: Application
    Filed: January 21, 2015
    Publication date: February 4, 2016
    Inventors: Masahiro OTA, Ryosuke UMEMURA
  • Patent number: 8933103
    Abstract: Novel compounds or salts thereof, or crystals thereof, which inhibit Axl and are useful for treating diseases caused by Axl hyperfunction, diseases associated with Axl hyperfunction and/or diseases accompanied by Axl hyperfunction are provided. Pyridone derivatives represented by the formula (1) having various substituents or salts thereof, or crystals thereof (where R1, R2, R3, R5, R6, A, W, X and n in the formula (1) are as defined in the specification, respectively) are provided.
    Type: Grant
    Filed: January 30, 2013
    Date of Patent: January 13, 2015
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Hitoshi Ohki, Masahiro Ota, Kosuke Takeuchi, Hideaki Watanabe, Akitake Yamaguchi, Yoshihiro Shibata, Yuichi Tominaga, Takeshi Jimbo, Keijiro Kobayashi, Katsuhiro Kobayashi, Daisuke Fukatsu
  • Patent number: 8828349
    Abstract: A substrate for growing carbon nanotubes capable of elongating single-walled carbon nanotubes of an average diameter of less than 2 nm is provided. The substrate for growing carbon nanotubes 1 is equipped with a reaction prevention layer 3 formed on a base material 2, a catalyst material layer 4 formed on the reaction prevention layer 3, a dispersion layer 5 formed on the catalyst material layer 4, and a dispersion promotion layer 6 formed on the dispersion layer 5.
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: September 9, 2014
    Assignees: Honda Motor Co., Ltd., Waseda University
    Inventors: Toshiyuki Ohashi, Toshio Tokune, Masahiro Ota, Hidefumi Nikawa, Hiroshi Kawarada, Takumi Ochiai