Abstract: The present application provides black perylene pigment microparticles having an average circularity of 0.8 or more which are amorphous; and a method of producing the black perylene pigment microparticles, which comprises a step of mixing a pigment solution in which a black perylene pigment is dissolved and a precipitation solvent for precipitating black perylene pigment microparticles from the pigment solution to form black perylene pigment microparticles, wherein at least one of the pigment solution and the precipitation solvent independently includes a salt of an alkaline earth metal and/or a particle growth inhibitor. The present invention can provide black perylene pigment microparticles having good dispersibility, high concealability and light-shielding property and controlled hue and chroma, and a method of easily producing the same, and the like.

Abstract: In a coloring ultraviolet protective agent, the average molar absorption coefficient in the wavelength range from 200 nm to 380 nm is increased, and the color characteristics in the visible region are controlled. The coloring ultraviolet protective agent is useful for shielding ultraviolet rays and coloring.

Abstract: The present application provides a microsphere comprising a lactic acid-glycolic acid copolymer (PLGA) as a main component, in which a biologically active substance is uniformly dispersed, wherein an average volume-based particle diameter of the microsphere is 1 ?m or more and 150 ?m or less, and a mass of the biologically active substance or an empty hole of 1.5 ?m or more is not present in the microsphere. The microsphere of the present invention can appropriately control the initial release amount of the biologically active substance and its release rate during a subsequent release period, and can continuously release the biologically active substance in vivo for a predetermined period of time.

Abstract: A heat exchanger includes a structure that is advantageous in increasing the overall heat transfer coefficient which represents the efficiency of heat exchange. Three flow paths, a first flow path, a second flow path, and a third flow path, which turn spirally in the space formed between an inner cylinder and an outer cylinder are provided. These flow paths are defined by an inner heat transfer body and an outer heat transfer body, and heat exchange is performed through the heat transfer bodies. The heat transfer bodies turn spirally, have a screw shape in an axial cross-sectional view, and are assembled into a screw shape. The flow path area of the first flow path is varied by changing the shapes of a male thread and a female thread, and the second flow path and the third flow path are formed in a spiral shape, allowing for exchange of heat through the heat transfer bodies.

Abstract: Provided are a method for producing organic material microparticles and a method for modifying organic material microparticles, whereby it becomes possible to improve the crystallinity of organic material microparticles or achieve the crystal transformation of the organic material microparticles while preventing the growth of the organic material microparticles in a solvent. A surfactant is added to a solvent that is capable of partially dissolving organic material microparticles, and then the organic material microparticles are reacted with the solvent. In this manner, it becomes possible to improve the degree of crystallization of the organic material microparticles or achieve the crystal transformation of the organic material microparticles without substantially altering the particle diameters of the organic material microparticles.

Abstract: The present application provides a microsphere in which a main agent is uniformly dispersed in a polymer matrix, wherein an average volume-based particle diameter of the microsphere is 1 ?m or more and 150 ?m or less, and a variation coefficient of area ratios in four regions is 0.35 or less, wherein the area ratios in four regions are calculated by (s/A)×100 (%) wherein the four regions are prepared by preparing a cross section observation sample obtained by cutting the microsphere; observing the cross section observation sample with an electron microscope at a magnification capable of confirming the main agent in the microsphere or a higher magnification; and dividing the electron microscope observation image into four regions; and A is an area of a respective divided region, and s is a sum of cross section areas of the main agent included in the respective divided region.

Abstract: Provided are a method for producing organic material microparticles and a method for modifying organic material microparticles, whereby it becomes possible to improve the crystallinity of organic material microparticles or achieve the crystal transformation of the organic material microparticles while preventing the growth of the organic material microparticles in a solvent. A surfactant is added to a solvent that is capable of partially dissolving organic material microparticles, and then the organic material microparticles are reacted with the solvent. In this manner, it becomes possible to improve the degree of crystallization of the organic material microparticles or achieve the crystal transformation of the organic material microparticles without substantially altering the particle diameters of the organic material microparticles.

Abstract: A method of producing an ultraviolet protective agent composition, which has high transparency and excellent protection ability against a light of ultraviolet region of wavelengths of 200 to 420 nm, and an ultraviolet protective agent composition obtained by the production method are provided. The method of producing an ultraviolet protective agent composition includes at least step (a) of precipitating iron oxide microparticles by mixing with a microreactor an iron oxide raw material fluid containing at least Fe3+ ion, and an iron oxide precipitation fluid containing at least a basic substance; and step (b) of dispersing the above precipitated iron oxide microparticles in a dispersion medium to obtain iron oxide microparticle dispersion, wherein a haze value of the iron oxide microparticle dispersion is 2.0% or less, and a transmittance of the iron oxide microparticle dispersion for the light of the wavelengths of 200 to 420 nm is 2.0% or less.

Abstract: A stirrer is provided that can more efficiently achieve shearing applied, by an action of an intermittent jet flow, to a fluid to be processed.

Abstract: The present application provides a microsphere in which a main agent is uniformly dispersed in a polymer matrix, wherein an average volume-based particle diameter of the microsphere is 1 ?m or more and 150 ?m or less, and a variation coefficient of area ratios in four regions is 0.35 or less, wherein the area ratios in four regions are calculated by (s/A)×100(%) wherein the four regions are prepared by preparing a cross section observation sample obtained by cutting the microsphere; observing the cross section observation sample with an electron microscope at a magnification capable of confirming the main agent in the microsphere or a higher magnification; and dividing the electron microscope observation image into four regions; and A is an area of a respective divided region, and s is a sum of cross section areas of the main agent included in the respective divided region.

Abstract: A method of producing an organic pigment composition including at least organic pigment microparticles, wherein a diffuse reflectance of the organic pigment microparticles is controlled for the purpose of improving a luminance of a color filter. The luminance of the color filter is controlled to be high, by controlling a ratio of an area of the diffuse reflectance in a target wavelength range to a total area of the diffuse reflectance in the entire measurement wavelength range in a diffuse reflection spectrum of the organic pigment microparticles in the wavelength range of 380 to 780 nm, to be high. The luminance of the color filter is controlled to be high, by coating at least a part of the surface of the organic pigment microparticles with an oxide.

Abstract: The object of the present invention is to provide silicon doped metal oxide particles for UV absorption, which average molar absorption coefficient in the wavelength range of 200 nm to 380 nm, is enhanced. Provided is silicon doped metal oxide particles in which the metal oxide particles are doped with silicon, wherein an average molar absorption coefficient in the wavelength range of 200 nm to 380 nm, of a dispersion in which the silicon doped metal oxide particles are dispersed in a dispersion medium, is improved as compared with similar metal oxide particles not doped with silicon.

Abstract: A forced thin film-type flow reactor is provided with a clearance adjustment mechanism that allows the clearance to be set and adjusted by an alternative means. The flow reactor processes a fluid to be processed by passing the fluid to be processed between a first processing surface and a second processing surface capable of moving towards and away from each other, and the flow reactor comprises a pressure balancing mechanism and a mechanical clearance mechanism. The pressure balancing mechanism forms a minute first clearance by providing pressure balance between the pressure applied by the fluid to be processed, which acts in the direction in which the first processing surface and the second processing surface move away from each other, and a force produced by a back pressure mechanism, which acts in the direction in which the first processing surface and the second processing surface move towards each other.

Abstract: A flow reactor is structured to increase the overall heat transfer coefficient, which represents the efficiency of heat exchange with respect to a reactive fluid to be treated. This flow reactor is provided with three flow passages, which are a first flow passage, a second flow passage, and a third flow passage which spirally circulate within a space formed between an inner tube and an outer tube. The flow passages are compartmented by an inner heat transfer body and an outer heat transfer bodies. The heat transfer bodies spirally circulate, have a screw-like cross-sectional shape in an axial cross-sectional view, and are assembled in a screw-like configuration. By changing the shapes of a male-thread portion and a female-thread portion, the flow passage area of the first flow passage is changed, the second flow passage and the third flow passage are spirally formed, and heat exchange and reaction take place through the heat transfer bodies.

Abstract: A heat exchanger with which a fluid to be treated or a generated gas can be prevented from stagnating in a heat transfer part, which can be disassembled for good washability, and which can be coated or lined. The heat exchanger is provided with tow flow passages, i.e. a first flow passage and a second flow passage, within a space formed between an inner tube and an outer tube which are concentric to each other. A spiral heat transfer body is disposed between the inner tube and the outer tube, and the spiral heat transfer body has a cross-sectional shape that is substantially triangular in the axial-direction cross section. The space is partitioned into the first flow passage and the second flow passage by the spiral heat transfer body, and heat is exchanged via the spiral heat transfer body between a first fluid flowing within the first flow passage and a fluid flowing within the second flow passage.

Abstract: A flow reactor can promote a reaction under appropriate temperature management, can precent reaction fluid or generated gas from being trapped in a heat transmission part, can be disassembled for easy cleaning, and to which a coating or lining can be applied. This flow reactor is provided with two flow paths, a reaction flow path and a second flow path, in a space formed between an inner cylinder and an outer cylinder that are concentric. A spiral heat transmission body is disposed between the inner cylinder and the outer cylinder, and the spiral heat transmission body has a substantially triangular cross-sectional shape in an axial cross-sectional view. The spiral heat transmission body partitions the space into the reaction flow path and the second flow path, and heat is exchanged via the spiral heat transmission body between a reaction fluid F1 flowing through the reaction flow path and a heat medium F2 flowing through the second flow path.

Abstract: Provided are an immediately-before-stirring-type fluid processing device and an immediately-before-stirring-type fluid processing method that can adjust or improve the final properties of a fluid to be processed that is introduced as a raw material into an annular flow channel of a microreactor employing the annular flow channel, which is formed between relatively rotating processing surfaces, as a flow channel in which fluid processing is performed. A fluid to be processed, which has been prepared in a fluid preparing system so as to be in an ideal state for reaction, is charged into a fluid processing device. The fluid processing device subjects the fluid to be processed to reaction processing in an annular flow channel, which is formed between two processing surfaces. A cylindrical stirring space is provided in the radially inner side of the annular flow channel, and a rotor and a screen are disposed inside the stirring space.

Abstract: In an agitator in which cavitation arising during treatment of a fluid being treated is suppressed, a stator part S is provided with a plurality of penetration parts in the circumferential direction of the stator part S, and a stator main part positioned between adjacent penetration parts.

Abstract: The present application provides black perylene pigment microparticles having an average circularity of 0.8 or more which are amorphous; and a method of producing the black perylene pigment microparticles, which comprises a step of mixing a pigment solution in which a black perylene pigment is dissolved and a precipitation solvent for precipitating black perylene pigment microparticles from the pigment solution to form black perylene pigment microparticles, wherein at least one of the pigment solution and the precipitation solvent independently includes a salt of an alkaline earth metal and/or a particle growth inhibitor. The present invention can provide black perylene pigment microparticles having good dispersibility, high concealability and light-shielding property and controlled hue and chroma, and a method of easily producing the same, and the like.

Abstract: A vacuum deaerator is provided with a refining device with which it is possible to suppress the occurrence of situations involving interrupted discharging and continuously discharge a material being treated that is highly viscous, etc. The vacuum deaerator introduces a liquid material being treated into a vessel having a vacuum therein to perform deaeration and then discharged the material being treated out of the vessel. A rotating rotor with refining device arranged in the vessel and a rotating discharge vane provided separately from the rotating rotor for the purpose of discharging the material being treated in the vessel out of the vessel are installed.