Patents by Inventor Masanobu Shinoda
Masanobu Shinoda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8950916Abstract: Disclosed is a vehicle light fitting unit that can include a plurality of light sources, a reflecting plane which diffusely reflects light emitted from the plurality of light sources, and a lens which emits the light, which is diffusely reflected by the reflecting plane, to a front direction. The plurality of light sources can each be provided so that a pitch between one light source and another light source adjacent to the one light source is shorter than a light path length from the one light source to the lens passing through the reflecting plane.Type: GrantFiled: June 23, 2011Date of Patent: February 10, 2015Assignees: Stanley Electric Co., Ltd., Honda Motor Co., Ltd.Inventors: Kazuya Makiuchi, Hidetaka Okada, Takuya Matsumaru, Takashi Futami, Koji Fukura, Michio Furukawa, Masanobu Shinoda, Hideto Hosoda, Masahiro Yamagiwa, Yuji Tsuchiya, Tomohiro Tsukada
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Patent number: 8436009Abstract: By oral administration of a compound represented by the following Formula (I): the blood level of Compound (IV): which has an excellent inhibitory action against blood coagulation factor VIIa and the anticoagulant action, reaches a level sufficient for expression of its pharmacological actions. Therefore, the compound of the present invention is useful as a therapeutic and/or prophylactic agent for diseases caused by thrombus formation.Type: GrantFiled: May 18, 2011Date of Patent: May 7, 2013Assignee: Eisai R&D Management Co., Ltd.Inventors: Richard Clark, Fumiyoshi Matsuura, Masanobu Shinoda, Shinsuke Hirota, Kazunobu Kira, Hiroshi Azuma, Atsushi Takemura, So Yasui, Kazutomi Kusano, Masaki Mikamoto, Takao Omae
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Publication number: 20130053563Abstract: By oral administration of a compound represented by the following Formula (I): the blood level of Compound (IV): which has an excellent inhibitory action against blood coagulation factor VIIa and the anticoagulant action, reaches a level sufficient for expression of its pharmacological actions. Therefore, the compound of the present invention is useful as a therapeutic and/or prophylactic agent for diseases caused by thrombus formation.Type: ApplicationFiled: May 18, 2011Publication date: February 28, 2013Applicant: EISAI R&D MANAGEMENT CO., LTD.Inventors: Richard Clark, Fumiyoshi Matsuura, Masanobu Shinoda, Shinsuke Hirota, Kazunobu Kira, Hiroshi Azuma, Atsushi Takemura, So Yasui, Kazutomi Kusano, Masaki Mikamoto, Takao Omae
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Patent number: 8124780Abstract: A novel chemical compound useful as a therapeutic or prophylactic agent for acid-related diseases is provided, which has an excellent inhibitory effect against gastric acid secretion, an excellent effect of maintaining the inhibitory effect against gastric acid secretion, thereby maintaining intragastric pH high for a long time, and having more safety and appropriate physicochemical stability. Provided is a compound represented by where R1 and R3 may be the same or different and each represent a hydrogen atom or a C1-C6 alkyl group; R2 represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy group, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy group, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy group, or (2,2-dimethyl-1,3-dioxan-5-yl)methoxy group; R4, R5, R6 and R7 represent a hydrogen atom, halogen atom, C1-C6 alkyl group, C1-C6 haloalkyl group, C1-C6 alkoxy group or C1-C6 haloalkoxy group; and W1 represents a single bond, methylene or ethylene group, a salt thereof or a solvate of these.Type: GrantFiled: August 11, 2008Date of Patent: February 28, 2012Assignee: Eisai R&D Management Co., Ltd.Inventors: Shuhei Miyazawa, Masanobu Shinoda, Tetsuya Kawahara, Nobuhisa Watanabe, Hitoshi Harada, Daisuke Iida, Hiroki Terauchi, Junichi Nagakawa, Hideaki Fujisaki, Atsuhiko Kubota, Masato Ueda
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Publication number: 20110317442Abstract: Disclosed is a vehicle light fitting unit that can include a plurality of light sources, a reflecting plane which diffusely reflects light emitted from the plurality of light sources, and a lens which emits the light, which is diffusely reflected by the reflecting plane, to a front direction. The plurality of light sources can each be provided so that a pitch between one light source and another light source adjacent to the one light source is shorter than a light path length from the one light source to the lens passing through the reflecting plane.Type: ApplicationFiled: June 23, 2011Publication date: December 29, 2011Inventors: Kazuya Makiuchi, Hidetaka Okada, Takuya Matsumaru, Takashi Futami, Koji Fukura, Michio Furukawa, Masanobu Shinoda, Hideto Hosoda, Masahiro Yamagiwa, Yuji Tsuchiya, Tomohiro Tsukada
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Patent number: 7816405Abstract: The present invention relates to calcium bis[(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy) -2-fluoropropoxy]phenyl]-2-isopropoxypropionate] represented by formula (I), a hydrate thereof, a crystal of the compound of formula (I), and a crystal of the hydrate of the compound of formula (I) which are useful as pharmaceuticals, and to processes for producing the same, and intermediates therefore, and processes for production thereof. There is need for (2S)-3-[3-[(2S)-3-(4 -chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionic acid, in the form of a drug substance, purified so as to minimize a residual solvent content and having a uniformized specification and a highly favorable workability, and a process for producing the same. Crystalline calcium bis[(2S)-3-[3-[(2S)-3-(4 -chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionate], a calcium salt of (2S) -3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionic acid, solves the above problem.Type: GrantFiled: April 18, 2006Date of Patent: October 19, 2010Assignee: Eisai R&D Management Co., Ltd.Inventors: Masanobu Shinoda, Fumiyoshi Matsuura, Kaoru Murata, Masaharu Gotoda, Kenji Hayashi, Manabu Sasho, Naoki Ozeki, Susumu Inoue, Katsutoshi Nishiura, Yoshihiko Hisatake, Teiji Takigawa, Mamoru Miyazawa, Shigeto Negi, Keisuke Matsuyama
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Patent number: 7687664Abstract: The present invention provides novel carboxylic acid derivatives useful as an insulin sensitizer, a salt thereof or a hydrate of them, and a medicament comprising the derivative as the active ingredient. Specifically, it provides a carboxylic acid derivative represented by the following formula (I): (wherein Y, L, X, T, Z, U, M and W are defined in the specification) and a salt thereof, and ester thereof or a hydrate of them.Type: GrantFiled: June 4, 2002Date of Patent: March 30, 2010Assignee: Eisai R&D Management Co., Ltd.Inventors: Fumiyoshi Matsuura, Eita Emori, Masanobu Shinoda, Richard Clark, Shunji Kasai, Hideki Yoshitomi, Kazuto Yamazaki, Takashi Inoue, Sadakazu Miyashita, Taro Hihara
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Publication number: 20090215795Abstract: A cyclic amidine derivative represented by the formula: [wherein R1, R2 and R3 represent hydrogen, C1-6 alkyl, aryl-C1-6 alkyl, etc.; R4, R5 and R7 represent hydrogen, C1-6 alkyl, etc.; Z represents 0 or 1; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; n represents 1 or 2; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; Ar represents hydrogen, a group represented by the formula: [wherein R10-R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc., and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocycle], etc.] or a salt thereof.Type: ApplicationFiled: July 17, 2008Publication date: August 27, 2009Applicant: EISAI R&D MANAGEMENT CO., LTD.Inventors: Shuichi Suzuki, Makoto Kotake, Mitsuaki Miyamoto, Tetsuya Kawahara, Akiharu Kajiwara, Ieharu Hishinuma, Kazuo Okano, Syuhei Miyazawa, Richard Clark, Fumihiro Ozaki, Nobuaki Sato, Masanobu Shinoda, Atsushi Kamada, Itaru Tsukada, Fumiyoshi Matsuura, Yoshimitsu Naoe, Taro Terauchi, Yoshiaki Oohashi, Osamu Ito, Hiroshi Tanaka, Takashi Musha, Motoji Kogushi, Tsutomu Kawata, Toshiyuki Matsuoka, Hiroko Kobayashi, Ken-ichi Chiba, Akifumi Kimura, Naoto Ono
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Publication number: 20090203911Abstract: A novel chemical compound useful as a therapeutic or prophylactic agent for acid-related diseases is provided, which has an excellent inhibitory effect against gastric acid secretion, an excellent effect of maintaining the inhibitory effect against gastric acid secretion, thereby maintaining intragastric pH high for a long time, and having more safety and appropriate physicochemical stability. Provided is a compound represented by where R1 and R3 may be the same or different and each represent a hydrogen atom or a C1-C6 alkyl group; R2 represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy group, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy group, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy group, or (2,2-dimethyl-1,3-dioxan-5-yl)methoxy group; R4, R5, R6 and R7 represent a hydrogen atom, halogen atom, C1-C6 alkyl group, C1-C6 haloalkyl group, C1-C6 alkoxy group or C1-C6 haloalkoxy group; and W1 represents a single bond, methylene or ethylene group, a salt thereof or a solvate of these.Type: ApplicationFiled: August 11, 2008Publication date: August 13, 2009Inventors: Shuhei MIYAZAWA, Masanobu Shinoda, Tetsuya Kawahara, Nobuhisa Watanabe, Hitoshi Harada, Daisuke Iida, Hiroki Terauchi, Junichi Nagakawa, Hideaki Fujisaki, Atsuhiko Kubota, Masato Ueda
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Patent number: 7544835Abstract: Carboxylic acid compound or salt or hydrate thereof useful as insulin sensitizer, represented by the formula wherein R1 represents hydrogen, hydroxyl, halogen, carboxyl, or C1-6 alkyl, L represents single bond or C1-6-alkylene, C2-6-alkenylene, or C2-6-alkynylene, M represents single bond or C1-6-alkylene, C2-6-alkenylene, or C2-6-alkynylene, T represents single bond, or C1-3-alkylene, C2-3-alkenylene, or C2-3-alkynylene, W represents carboxyl, represents single bond, X represents single bond, oxygen, —NRX1CQ1O—, —OCQ1NRX1—, —CQ1NRX1O—, ONRX1CQ1—, —Q2SO2—, or —SO2Q2—, Y represents 5- to 14-membered aromatic group, and ring Z represents 5- to 14-membered aromatic group.Type: GrantFiled: April 18, 2002Date of Patent: June 9, 2009Assignee: Eisai R&D Management Co., Ltd.Inventors: Fumiyoshi Matsuura, Eita Emori, Masanobu Shinoda, Richard Clark, Shunji Kasai, Hideki Yoshitomi, Kazuto Yamazaki, Takashi Inoue, Sadakazu Miyashita, Taro Hihara, Hitoshi Harada, Kaya Ohashi
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Publication number: 20090069591Abstract: The present invention relates to calcium bis[(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionate] represented by formula (I), a hydrate thereof, a crystal of the compound of formula (I), and a crystal of the hydrate of the compound of formula (I) which are useful as pharmaceuticals, and to processes for producing the same, and intermediates therefore, and processes for production thereof. [Problem] There is need for (2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionic acid, in the form of a drug substance, purified so as to minimize a residual solvent content and having a uniformized specification and a highly favorable workability, and a process for producing the same. [Solution] Crystalline calcium bis[(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionate], a calcium salt of (2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionic acid, solves the above problem.Type: ApplicationFiled: April 18, 2006Publication date: March 12, 2009Applicant: EISAI R & D MANAGEMENT CO., LTD.Inventors: Masanobu Shinoda, Fumiyoshi Matsuura, Kaoru Murata, Masaharu Gotoda, Kenji Hayashi, Manabu Sasho, Naoki Ozeki, Susumu Inoue, Katsutoshi Nishiura, Yoshihiko Hisatake, Teiji Takigawa, Mamoru Miyazawa, Shigeto Negi, Keisuke Matsuyama
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Patent number: 7476688Abstract: A cyclic amidine derivative represented by the formula: [wherein R1, R2 and R3 represent hydrogen, C1-6 alkyl, aryl-C1-6 alkyl, etc.; R4, R5 and R7 represent hydrogen, C1-6 alkyl, etc.; Z represents 0 or 1; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; n represents 1 or 2; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; Ar represents hydrogen, a group represented by the formula: [wherein R10-R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc., and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocycle], etc.] or a salt thereof.Type: GrantFiled: April 19, 2002Date of Patent: January 13, 2009Assignee: EISAI R&D Management Co., Ltd.Inventors: Shuichi Suzuki, Masanobu Shinoda, Motoji Kogushi, Hiroko Kobayashi
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Patent number: 7425634Abstract: An object of the present invention is to provide a novel chemical compound useful as a therapeutic or prophylactic agent for acid-related diseases, having an excellent inhibitory effect against gastric acid secretion, an excellent effect of maintaining the inhibitory effect against gastric acid secretion, thereby maintaining intragastric pH high for a long time, and having more safety and appropriate physicochemical stability. Provided is a compound represented by where R1 and R3 may be the same or different and each represent a hydrogen atom or a C1-C6 alkyl group; R2 represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy group, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy group, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy group, or (2,2-dimethyl-1,3-dioxan-5-yl)methoxy group; R4, R5, R6 and R7 represent a hydrogen atom, halogen atom, C1-C6 alkyl group, C1-C6 haloalkyl group, C1-C6 alkoxy group or C1-C6 haloalkoxy group; and W1 represents a single bond, methylene or ethylene group, a salt thereof or a solvate of these.Type: GrantFiled: September 14, 2006Date of Patent: September 16, 2008Assignee: Eisai R&D Management Co., Ltd.Inventors: Shuhei Miyazawa, Masanobu Shinoda, Tetsuya Kawahara, Nobuhisa Watanabe, Hitoshi Harada, Daisuke Iida, Hiroki Terauchi, Junichi Nagakawa, Hideaki Fujisaki, Atsuhiko Kubota, Masato Ueda
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Patent number: 7371777Abstract: The present invention provides a novel compound having an excellent PPAR agonist action. More specifically, it provides a compound represented by the following formula, a salt thereof, an ester thereof or a hydrate of them. Wherein a, b and c are the same as or different from one another and each represents 0 to 4; R1 to R6 are the same as or different from one another and each represents a hydrogen atom, a hydroxyl group, a cyano group, a halogen atom, etc.; A1 and A2 are the same as or different from each other and each represents a single bond, an oxygen atom, etc.; L, M and T each represent a single bond, an alkylene group having one to six carbon atoms, etc.; W represents a carboxyl group; the partial structure represented by the formula: represents a single bond or a double bond; X represents a single bond, an oxygen atom, —NRx1CQ1O—, etc.; Y represents Y1—Y2— (wherein Y1 represents a 5 to 14-membered aromatic ring having one to four substituents, etc.Type: GrantFiled: August 16, 2002Date of Patent: May 13, 2008Assignee: Eisai Co., Ltd.Inventors: Richard Clark, Fumiyoshi Matsuura, Eita Emori, Masanobu Shinoda, Shunji Kasai, Hideki Yoshitomi, Kazuto Yamazaki, Takashi Inoue, Sadakazu Miyashita, Taro Hihara
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Patent number: 7304083Abstract: A 2-iminoimidazole derivative represented by the formula: {wherein R1, R2 and R3 represent hydrogen, optionally substituted C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10–R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc., and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocycle], etc.}or salt thereof.Type: GrantFiled: April 19, 2002Date of Patent: December 4, 2007Assignee: Eisai R&D Management Co., Ltd.Inventors: Shuichi Suzuki, Makoto Kotake, Mitsuaki Miyamoto, Tetsuya Kawahara, Akiharu Kajiwara, Ieharu Hishinuma, Kazuo Okano, Syuhei Miyazawa, Richard Clark, Fumihiro Ozaki, Nobuaki Sato, Masanobu Shinoda, Atsushi Kamada, Itaru Tsukada, Fumiyoshi Matsuura, Yoshimitsu Naoe, Taro Terauchi, Yoshiaki Oohashi, Osamu Ito, Hiroshi Tanaka, Takashi Musha, Motoji Kogushi, Tsutomu Kawata, Toshiyuki Matsuoka, Hiroko Kobayashi, Ken-ichi Chiba, Akifumi Kimura, Naoto Ono
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Patent number: 7253178Abstract: The present invention provides a novel carboxylic acid derivative, a salt thereof or a hydrate of them which is useful as an insulin sensitizer, and a medicament comprising the derivative as the effective ingredient. More specifically, it provides a carboxylic acid compound represented by the formula (I), a salt thereof or a hydrate of them.Type: GrantFiled: March 27, 2002Date of Patent: August 7, 2007Assignee: Eisai Co., Ltd.Inventors: Hitoshi Harada, Masanobu Shinoda, Richard Clark, Fumiyoshi Matsuura, Eita Emori, Shunji Kasai, Hideki Yoshitomi, Kazuto Yamazaki, Takashi Inoue, Sadakazu Miyashita, Taro Hihara
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Patent number: 7244730Abstract: A 2-iminopyrrolidine derivative represented by the formula: {wherein ring B represents a benzene ring, pyridine ring, etc.; R101–R103 represent hydrogen, halogen, C1-6 alkyl, etc.; R5 represents hydrogen, C1-6 alkyl, C1-6 alkoxy-C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10—R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc.; and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocyclic ring], etc.}, or a salt thereof.Type: GrantFiled: April 19, 2002Date of Patent: July 17, 2007Assignee: Eisai Co., LtdInventors: Shuichi Suzuki, Makoto Kotake, Mitsuaki Miyamoto, Tetsuya Kawahara, Akiharu Kajiwara, Ieharu Hishinuma, Kazuo Okano, Syuhei Miyazawa, Richard Clark, Fumihiro Ozaki, Nobuaki Sato, Masanobu Shinoda, Atsushi Kamada, Itaru Tsukada, Fumiyoshi Matsuura, Yoshimitsu Naoe, Taro Terauchi, Yoshiaki Oohashi, Osamu Ito, Hiroshi Tanaka, Takashi Musya, Motoji Kogushi, Tsutomu Kawada, Toshiyuki Matsuoka, Hiroko Kobayashi, Ken-ichi Chiba, Akifumi Kimura, Naoto Ono
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Patent number: 7244861Abstract: The present invention provides a medicament comprising a benzene compound useful as an insulin sensitizer, a salt thereof or a hydrate of them and a derivative of them as the active ingredient. Specifically, it provides a benzene compound represented by the following formula, a salt thereof or a hydrate of them. In the formula, X represents 1) a C6-10 aryl group which may have one or more substituents or 2) a 5- to 10-membered heteroaryl group which may have one or more substituents; Y represents a group represented by the formula: (in the above formulae, Ry1, Ry2 and Ry3 are the same as or different from one another and each represents a hydrogen atom, a halogen atom, a C1-6 alkyl group, a C1-6 alkoxy group, or a C3-7 cycloalkyl group) etc.Type: GrantFiled: March 27, 2002Date of Patent: July 17, 2007Assignee: Eisai Co., Ltd.Inventors: Fumiyoshi Matsuura, Eita Emori, Masanobu Shinoda, Richard Clark, Shunji Kasai, Hideki Yoshitomi, Kazuto Yamazaki, Takashi Inoue, Sadakazu Miyashita, Taro Hihara
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Publication number: 20070117866Abstract: The present invention relates to calcium bis[(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionate] represented by formula (I), a hydrate thereof, a crystal of the compound of formula (I), and a crystal of the hydrate of the compound of formula (I) which are useful as pharmaceuticals, and to processes for producing the same, and intermediates therefore, and processes for production thereof. [Problem]There is need for (2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionic acid, in the form of a drug substance, purified so as to minimize a residual solvent content and having a uniformized specification and a highly favorable workability, and a process for producing the same. [Solution]Crystalline calcium bis[(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionate], a calcium salt of (2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionic acid, solves the above problem.Type: ApplicationFiled: April 18, 2006Publication date: May 24, 2007Applicant: Eisai Co., Ltd.Inventors: Masanobu Shinoda, Fumiyoshi Matsuura, Kaoru Murata, Masaharu Gotoda, Kenji Hayashi, Manabu Sasho, Naoki Ozeki, Susumu Inoue, Katsutoshi Nishiura, Yoshihiko Hisatake, Teiji Takigawa, Mamoru Miyazawa, Shigeto Negi, Keisuke Matsuyama
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Publication number: 20070015782Abstract: An object of the present invention is to provide a novel chemical compound useful as a therapeutic or prophylactic agent for acid-related diseases, having an excellent inhibitory effect against gastric acid secretion, an excellent effect of maintaining the inhibitory effect against gastric acid secretion, thereby maintaining intragastric pH high for a long time, and having more safety and appropriate physicochemical stability. Provided is a compound represented by where R1 and R3 may be the same or different and each represent a hydrogen atom or a C1-C6 alkyl group; R2 represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy group, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy group, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy group, or (2,2-dimethyl-1,3-dioxan-5-yl)methoxy group; R4, R5, R6 and R7 represent a hydrogen atom, halogen atom, C1-C6 alkyl group, C1-C6 haloalkyl group, C1-C6 alkoxy group or C1-C6 haloalkoxy group; and W1 represents a single bond, methylene or ethylene group, a salt thereof or a solvate of these.Type: ApplicationFiled: April 14, 2006Publication date: January 18, 2007Inventors: Shuhei Miyazawa, Masanobu Shinoda, Tetsuya Kawahara, Nobuhisa Watanabe, Hitoshi Harada, Daisuke Iida, Hiroki Terauchi, Junichi Nagakawa, Hideaki Fujisaki, Atsuhiko Kubota, Masato Ueda