Abstract: The present invention relates to an actinic radiation-curable inkjet ink including a photocurable compound, a photopolymerization initiator, and an unsaturated fatty acid ester having no photopolymerizable group. The content of the unsaturated fatty acid ester is 0.3 mass % or more and 4.5 mass % or less based on the total mass of the inkjet ink, and the unsaturated fatty acid ester is a compound having an iodine value of less than 80.

Abstract: The purpose of the present invention is to provide an active light ray-curable inkjet ink composition which exhibits excellent curing properties and high storage stability. This active light ray-curable inkjet ink composition contains a curable monomer, a photopolymerization initiator, an amine-modified oligomer, a pigment and a polymer dispersing agent. In this composition, the content of the amine-modified oligomer is 0.5-10 mass % relative to the overall mass of the active light ray-curable inkjet ink composition, the polymer dispersing agent is a compound which adsorbs the pigment and contains a tertiary amine group as a functional group, and the content of the polymer dispersing agent is 20-70 mass % relative to the pigment.

Abstract: An active ray curable inkjet ink includes: a radical polymerizable compound; a radical polymerization initiator; a color material; and an odor material scavenger, wherein the radical polymerization initiator is a compound producing aldehyde, the radical polymerizable compound contains a monofunctional radical polymerizable compound in an amount of 0 mass % to 10 mass % with respect to the total mass of the ink, the odor material scavenger is a compound having a primary amine group or secondary amine group and having a molecular weight of 1000 or less, or is a compound having a hydroxyl group or a compound having an aromatic ring-substituted hydroxyl group and having a molecular weight of 1000 or less, the content of the odor material scavenger is lower than that of the radical polymerization initiator, and the absorbance of the inkjet ink to light having a wavelength of 365 nm to 395 nm is 400 to 1000.

Abstract: The purpose of the present invention is to provide an active light ray-curable inkjet ink composition which exhibits excellent curing properties and high storage stability. This active light ray-curable inkjet ink composition contains a curable monomer, a photopolymerization initiator, an amine-modified oligomer, a pigment and a polymer dispersing agent. In this composition, the content of the amine-modified oligomer is 0.5-10 mass % relative to the overall mass of the active light ray-curable inkjet ink composition, the polymer dispersing agent is a compound which adsorbs the pigment and contains a tertiary amine group as a functional group, and the content of the polymer dispersing agent is 20-70 mass % relative to the pigment.

Abstract: An object of the present invention is to provide a photocurable inkjet ink having favorable discharge stability and a reduced odor. The photocurable inkjet ink of the present invention contains a photopolymerizable compound, a photopolymerization initiator, and a gelling agent; the content of the gelling agent is 0.5 mass % or more to 10 mass % or less based on the photocurable inkjet ink; and the photocurable inkjet ink further contains 10 mass ppm or more to 100 mass ppm or less of the compound which has a molecular weight of 200 or less and which contains a hydrophobic moiety having four or more carbon atoms Sbased on the photocurable inkjet ink.

Abstract: A photocurable composition containing a photopolymerizable compound and a photoinitiator, wherein the photopolymerizable compound is a radically polymerizable monomer and the photoinitiator is a photoradical initiator. The photocurable composition is characterized by additionally contains a metal chelate compound, wherein the center metal element in the metal chelate compound is selected from metal elements belonging to Group 2, Group 4, Group 8 and Group 13 and the metal chelate compound is contained in an amount of 0.1 to 5% by mass inclusive relative to the whole mass of the photocurable composition. Thus, it becomes possible to provide: a photocurable composition which has sustained adhesiveness and does not undergo shrinking upon curing; and a photocurable inkjet ink.

Abstract: A photocurable composition containing a photopolymerizable compound and a photoinitiator, wherein the photopolymerizable compound is a radically polymerizable monomer and the photoinitiator is a photoradical initiator. The photocurable composition is characterized by additionally contains a metal chelate compound, wherein the center metal element in the metal chelate compound is selected from metal elements belonging to Group 2, Group 4, Group 8 and Group 13 and the metal chelate compound is contained in an amount of 0.1 to 5% by mass inclusive relative to the whole mass of the photocurable composition. Thus, it becomes possible to provide: a photocurable composition which has sustained adhesiveness and does not undergo shrinking upon curing; and a photocurable inkjet ink.

Abstract: An active ray curable inkjet ink includes: a radical polymerizable compound; a radical polymerization initiator; a color material; and an odor material scavenger, wherein the radical polymerization initiator is a compound producing aldehyde, the radical polymerizable compound contains a monofunctional radical polymerizable compound in an amount of 0 mass % to 10 mass % with respect to the total mass of the ink, the odor material scavenger is a compound having a primary amine group or secondary amine group and having a molecular weight of 1000 or less, or is a compound having a hydroxyl group or a compound having an aromatic ring-substituted hydroxyl group and having a molecular weight of 1000 or less, the content of the odor material scavenger is lower than that of the radical polymerization initiator, and the absorbance of the inkjet ink to light having a wavelength of 365 nm to 395 nm is 400 to 1000.

Abstract: An object of the present invention is to provide a photocurable inkjet ink having favorable discharge stability and a reduced odor. The photocurable inkjet ink of the present invention contains a photopolymerizable compound, a photopolymerization initiator, and a gelling agent; the content of the gelling agent is 0.5 mass % or more to 10 mass % or less based on the photocurable inkjet ink; and the photocurable inkjet ink further contains 10 mass ppm or more to 100 mass ppm or less of the compound which has a molecular weight of 200 or less and which contains a hydrophobic moiety having four or more carbon atoms Sbased on the photocurable inkjet ink.

Abstract: A method of designing an anti-allergic agent, sleep controlling agent, anti-obesity agent and remedy for brain injury acting via the inhibition of biosynthesis of prostaglandin D2. Crystal of a complex of human origin hematopoietic prostaglandin D synthase, glutathione, and a substrate analog or an inhibitor, etc are prepared and the three-dimensional structural coordinate of each atom in the complex is determined by X-ray crystal analysis.

Abstract: A method of designing an anti-allergic agent, sleep controlling agent, anti-obestic agent and remedy for brain injury acting via the inhibition of biosynthesis of prostaglandin D2. Crystal of a complex of human origin hematopoietic prostaglandin D synthase, glutathione, and a substrate analog or an inhibitor, etc are prepared and the three-dimensional structural coordinate of each atom in the complex is determined by X-ray crystal analysis.

Abstract: An object of the present invention is to provide a method which is able to prevent or improve the progress of myolytic diseases such as muscular dystrophy. Such an object is able to be solved by a method where an effective dose of an inhibitor for hematopoietic prostaglandin D synthase (H-PGDS) or an antagonist to prostaglandin D receptor is administered to a patient who needs it. The present invention also provides a method for screening compounds which are able to prevent the progress of myolytic diseases and to improve it using human H-PGDS overexpressed transgenic mice.

Abstract: An HCV polymerase suitable for crystal structural analysis and a method for using the enzyme are provided. The HCV polymerase suitable for crystal structural analysis and/or comprising high HCV polymerase activity can be used for the three-dimensional structural analysis, and for rational identification of HCV polymerase inhibitors by computers. The enzyme can also be used for efficiently evaluating the HCV polymerase-inhibitory activity. The evaluation can be more efficiently performed by combining identification by computers.

Abstract: An object of the present invention is to provide a method which is able to prevent or improve the progress of myolytic diseases such as muscular dystrophy. Such an object is able to be solved by a method where an effective dose of an inhibitor for hematopoietic prostaglandin D synthase (H-PGDS) or an antagonist to prostaglandin D receptor is administered to a patient who needs it. The present invention also provides a method for screening compounds which are able to prevent the progress of myolytic diseases and to improve it using human H-PGDS overexpressed transgenic mice.

Abstract: It is intended to provide a method of designing an antiallergic agent, a sleep controlling agent, an antiobestic and a remedy for brain injury acting via the inhibition of the biosynthesis of prostaglandin D2. Crystals of a complex of human-origin hematopoietic prostaglandin D synthase, glutathione and a substrate analog or an inhibitor, etc. are prepared and the three-dimensional structural coordinate of each atom in the complex is determined by X-ray crystal analysis.

Abstract: A crystal evaluating device including a sample stage on which an X-ray permeable sample holder 40 having at least one crystal sample mounted therein can be mounted in a substantially horizontal position, an X-ray irradiating unit 20 for irradiating X-rays to the crystal sample in the sample holder 40 disposed on the sample stage from an upper side or lower side, and an X-ray detector 30 for detecting diffracted X-rays from the crystal sample. The X-ray irradiating unit 20 and the X-ray detector 30 are mounted on a rotational arm 50 which can be rotated around the substantially horizontal axis by a rotational driving mechanism 51.

Abstract: In the method of the invention for crystallization of proteins and the like, test substances prepared by mixing a sample of a protein and the like and reagents which promote the crystallization of the sample are put into test-substance wells of containers, such as microplates, and transferred to an analysis process, such as an X-ray crystal structural analysis, to perform an information analysis of the sample.

Abstract: The present invention discloses a three-dimensional structure of bovine rhodopsin.

Abstract: An antiviral protein having an amino acid sequence represented by sequence No. 8 of a Sequence Listing is disclosed. The protein is obtained such that cysteine residues in the basic protein (MAP) obtained from Mirabilis jalapa and having antiviral activity are substituted with serine residues. More specifically, a MAP gene in which codons encoding cysteines are substituted with codons encoding serines is prepared, and this gene is integrated in a MAP secretion vector. This vector is introduced into a host to express the gene, thereby obtaining the antiviral protein. This protein retains MAP advantages as a toxic protein and has higher protein synthesis inhibition activity than that of MAP, and almost equal to that of a lysine A chain.