Abstract: A developer supply container includes a developer accommodating portion having one end provided with an opening, and drive receiving portion, a discharging portion including a receiving portion into which the one end of the accommodating portion is inserted, and a developer discharge opening, the accommodating portion being mounted to the discharging portion rotatably relative to the discharging portion; a sealing member sealing between the one end and the receiving portion; a projection radially projecting from an outer peripheral surface of the accommodating portion; and a first restricting portion and a second restricting portion provided on the receiving portion of the discharging portion at positions upstream and downstream of the projection, respectively in the inserting direction and contactable to the projection to restrict an inclination of the rotational axis of the accommodating portion relative to the inserting direction within a predetermined range.

Abstract: A peptide which can be utilized as an active ingredient of a composition for use in stimulation of migration of PDGFR?-positive cells, a composition for use in recruitment of bone marrow mesenchymal stem cells from bone marrow to peripheral blood, a composition for use in regeneration of tissues, or a composition for use in stimulation of migration of bone marrow-derived stromal cells is provided.

Abstract: A developer supply container includes an accommodating portion, a discharging portion, a sealing member, a first restricting portion, and a second restricting portion positioned upstream of the first restricting portion with respect to an inserting direction of the accommodating portion. The seal member is provided between the first restricting portion and the second restricting portion with respect to a rotational axis direction of the accommodating portion.

Abstract: A developer supply container includes an accommodating portion, a discharging portion, a sealing member, a first restricting portion, and a second restricting portion positioned upstream of the first restricting portion with respect to an inserting direction of the accommodating portion. The seal member is provided between the first restricting portion and the second restricting portion with respect to a rotational axis direction of the accommodating portion.

Abstract: A developer supply container includes a developer accommodating portion having one end provided with an opening, and drive receiving portion, a discharging portion including a receiving portion into which the one end of the accommodating portion is inserted, and a developer discharge opening, the accommodating portion being mounted to the discharging portion rotatably relative to the discharging portion; a sealing member sealing between the one end and the receiving portion; a projection radially projecting from an outer peripheral surface of the accommodating portion; and a first restricting portion and a second restricting portion provided on the receiving portion of the discharging portion at positions upstream and downstream of the projection, respectively in the inserting direction and contactable to the projection to restrict an inclination of the rotational axis of the accommodating portion relative to the inserting direction within a predetermined range.

Abstract: The object of the present invention is to provide novel compounds having ACC2 inhibiting activity. In addition, the object of the present invention is to provide a pharmaceutical composition comprising the compound. A compound of formula (I): wherein R1 is substituted or unsubstituted fused aromatic heterocyclyl etc., ring A is substituted or unsubstituted non-aromatic carbocycle etc., -L1- is —O—(CR6R7)m- etc., -L2- is —O—(CR6R7)n- etc., each R6 and R7 are independently hydrogen, halogen etc., R2 is substituted or unsubstituted alkyl, R3 is hydrogen or substituted or unsubstituted alkyl, R4 is substituted or unsubstituted alkylcarbonyl etc.

Abstract: A stretching roller for stretching an intermediate transfer belt is tiltably disposed, and includes a sliding ring unrotatably disposed at both axial ends of a roller portion. The intermediate transfer belt winds and slidably rotates around the sliding ring. The sliding ring has a tapered portion inclined so that the outer diameter increases toward the axial end side of the stretching roller. The tapered portion is formed so that the inclination angle with respect to the central axis of the stretching roller differs at least in part in the circumferential direction.

Abstract: The object of the present invention is to provide novel compounds having ACC2 inhibiting activity. In addition, the object of the present invention is to provide a pharmaceutical composition comprising the compound. A compound of formula (I): wherein R1 is substituted or unsubstituted fused aromatic heterocyclyl etc., ring A is substituted or unsubstituted non-aromatic carbocycle etc., -L1- is —O—(CR6R7)m- etc., -L2- is —O—(CR6R7)n- etc., each R6 and R7 are independently hydrogen, halogen etc., R2 is substituted or unsubstituted alkyl, R3 is hydrogen or substituted or unsubstituted alkyl, R4 is substituted or unsubstituted alkylcarbonyl etc.

Abstract: In response to an arrival of a first cleaning region of the cleaning sheet to a pre-registration roller pair, a control portion drives the pre-registration roller pair for a predetermined time and cleans the pre-registration roller pair by the first cleaning region by stopping a fed sheet drawing roller pair and a registration roller pair. Then, after an elapse of the predetermined time, as the cleaning sheet is conveyed and a second cleaning region of the cleaning sheet arrives at the registration roller pair, the control portion cleans the registration roller pair by the second cleaning region.

Abstract: The invention relates to a sheet conveying apparatus which includes: a rotator pair which includes a nip portion to nip and convey a sheet conveyed by a sheet conveying portion; a first moving portion which includes a first contact surface abutting on the sheet on an upstream of the nip portion of the rotator pair in a sheet conveying direction, the first contact surface moving while being pressed by the sheet; a second moving portion which includes a second contact surface abutting on the sheet on the upstream of the nip portion of the rotator pair in the sheet conveying direction, the second contact surface moving while being pressed by the sheet; and a guide portion which guides a leading edge of the sheet conveyed by the sheet conveying portion selectively to the first contact surface of the first moving portion and the second contact surface of the second moving portion.

Abstract: The invention relates to a sheet conveying apparatus which includes: a rotator pair which includes a nip portion to nip and convey a sheet conveyed by a sheet conveying portion; a first moving portion which includes a first contact surface abutting on the sheet on an upstream of the nip portion of the rotator pair in a sheet conveying direction, the first contact surface moving while being pressed by the sheet; a second moving portion which includes a second contact surface abutting on the sheet on the upstream of the nip portion of the rotator pair in the sheet conveying direction, the second contact surface moving while being pressed by the sheet; and a guide portion which guides a leading edge of the sheet conveyed by the sheet conveying portion selectively to the first contact surface of the first moving portion and the second contact surface of the second moving portion.

Abstract: A drawing-in device configured to draw and position a sheet feeding cassette functioning as a unit into a predetermined position of an apparatus main body includes an engage-target tip. The engage-target tip is pressed in the mounting direction of the unit, thus the engage-target tip retreats from a locking position, where a latching pin is locked so as not to disengage, to a retreat position, where the latching pin can engage with the engage-target portion.

Abstract: The present invention relates to a filtration method, a filter-incorporated tip and a filtration device, and its object is to perform efficient and swift isolation of a target substance.

Abstract: The present invention related to providing a novel medicine for treating diabetes. It is possible to provide a GLP-1 derivative which is resistant to enzyme degradation by glycosylation of the peptide side chain.

Abstract: The present invention relates to a filtration method, a filter-incorporated tip and a filtration device, and its object is to perform efficient and swift isolation of a target substance.

Abstract: Disclosed herein are a novel crystal of a novel triterpene derivative, a method for producing the crystals, and a pharmaceutical preparation obtained by using the crystals.

Abstract: The invention aims at providing novel compounds useful as primer in producing mucin-type glycopeptides which are useful in a wide field including materials for biochemical research, drugs, and food and the production of which was difficult in the prior art; and a process for the production of glycopeptides by using the primers. The aim is attained by providing novel glycopeptide derivatives (represented by the general formula (I)) which each bear an aldehyde or ketone group at the end and each contain an amino acid residue cleavable with a protease; and an easy and simple process for the production of glycopeptides by using the derivative as the primer.

Abstract: Disclosed herein are a novel crystal of a novel triterpene derivative, a method for producing the crystals, and a pharmaceutical preparation obtained by using the crystals.