Patents by Inventor Masato Nakayama
Masato Nakayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20060223811Abstract: A blood triglyceride depressant composition which comprises pravastatin and one or more members selected from the group consisting of (1) pantethine, (2) inositol hexanicotinate, (3) a combination drug containing a riboflavin compound, a tocopherol compound and an ascorbic acid compound, and (4) a combination drug containing a tocopherol compound and an ascorbic acid compound.Type: ApplicationFiled: June 6, 2006Publication date: October 5, 2006Applicant: SANKYO COMPANY, LIMITEDInventors: Tsuneki Ohsawa, Ikuo Takagi, Ippei Shimizu, Tatsuhito Kondo, Masato Nakayama, Yasuhiro Torizumi
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Publication number: 20060140334Abstract: An X-ray CT apparatus comprises an X-ray generation device which generates X-rays, an X-ray detector which detects the X-rays having passed through a subject and outputs projection data, an imaging control device which controls the X-ray generation device and the X-ray detector so as to collect projection data, an image reconstruction device which reconstructs image data from the projection data, an image display device which displays an image on the basis of the image data, an image selection information addition device which adds, to the image data, the image selection information for the image data, an image selection device which judges presence/absence of an image analysis process on the basis of the image selection information and selects the image data, and an image analysis processing device which performs the image analysis process on the basis of the image data-selected by the image selection device.Type: ApplicationFiled: February 12, 2004Publication date: June 29, 2006Inventors: Hideki Imaizumi, Masato Nakayama
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Patent number: 7054759Abstract: A concentration measuring method includes selecting a calibration curve optimum for computing the concentration of a measurement target substance from a plurality of calibration curves based on an output from a reaction system containing the target substance and a reactant capable of reacting with the target substance, and computing the concentration of the target substance based on the optimum calibration curve and the output. Each of the calibration curves is prepared based on a plurality of outputs generated upon lapse of a same reaction time from a plurality of standard reaction systems each containing a standard reagent of a known different concentration and the reactant. The plurality of calibration curves differ from each other in reaction time based on which the calibration curves are prepared.Type: GrantFiled: December 25, 2002Date of Patent: May 30, 2006Assignee: ARKRAY, IncInventors: Satoshi Fukunaga, Masato Nakayama
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Patent number: 7037934Abstract: A blood lipid ameliorating composition containing atorvastatin in combination with an agent selected from the group consisting of a riboflavin derivative, a tocopherol compound, an ascorbic acid derivative, pantethine and taurine.Type: GrantFiled: June 11, 2003Date of Patent: May 2, 2006Assignee: Sankyo Company, LimitedInventors: Tsuneki Ohsawa, Ikuo Takagi, Ippei Shimizu, Tatsuhito Kondo, Masato Nakayama, Yasuhiro Torizumi
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Patent number: 7012067Abstract: A blood lipid ameliorating composition containing simvastatin and one or more ingredients selected from a riboflavin compound, a d-?-tocopherol compound, an ascorbic acid compound, pantethine, and taurine.Type: GrantFiled: June 12, 2003Date of Patent: March 14, 2006Assignee: Sankyo Company, LimitedInventors: Tsuneki Ohsawa, Ikuo Takagi, Ippei Shimizu, Tatsuhito Kondo, Masato Nakayama, Yasuhiro Torizumi
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Patent number: 6998422Abstract: Compositions having excellent blood lipid peroxide lowering activity are provided. In particular, compositions for lowering lipid peroxides in the blood which contain pravastatin together with at least one substance selected from the group consisting of taurine, pantethine and inositol hexanicotinate. Use of these compositions enables the provision of excellent preventive or remedial agents capable of lowering the concentration of lipid peroxides in the blood which show effects of injuring vascular endothelial cells, accelerating platelet aggregation, forming foam cells, etc.Type: GrantFiled: May 2, 2003Date of Patent: February 14, 2006Assignee: Sankyo Company, LimitedInventors: Tsuneki Ohsawa, Ikuo Takagi, Ippei Shimizu, Tatsuhito Kondo, Masato Nakayama, Yasuhiro Torizumi
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Publication number: 20060003325Abstract: The present invention provides a nucleotide mutation detection method wherein primers having a nucleotide sequence complementary to part of the nucleic acids to be detected and also having a nucleotide sequence, which is complementary to the nucleotide sequence just upstream from a nucleotide site corresponding to the mutation site of the nucleotide sequence formed at the 3? end, added to the 5? end, are produced so that so that the nucleotide site corresponding to the mutation site of the nucleic acids to be detected including the nucleotide mutation is located within the nucleotide sequence formed at the 3? end after elongation; a target is produced by subjecting the primers to an elongation reaction using polymerase or Klenow enzyme; the target is then denatured to a single strand, and is subjected to a hybridization reaction with a probe that has the nucleotide complementary to the mutation site of the nucleic acids present in the 3? end region and then to a ligation reaction, whereby it is enable to deteType: ApplicationFiled: July 30, 2003Publication date: January 5, 2006Applicant: TUM Gene, Inc.Inventor: Masato Nakayama
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Publication number: 20050187204Abstract: A pharmaceutical composition for lowering blood lipid levels which contains an HMG-CoA reductase inhibitor and bile acids. For treatment, the components of the composition can be administered together, as a composition, or separately.Type: ApplicationFiled: January 27, 2005Publication date: August 25, 2005Applicant: SANKYO COMPANY, LIMITEDInventors: Tatsuhito Kondo, Ikuo Takagi, Masato Nakayama, Yasuhiro Torizumi
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Publication number: 20050182036Abstract: A pharmaceutical composition for promoting the synthesis of vascular endothelial nitrogen oxide and/or maintaining or elevating the concentration of vascular endothelial nitrogen oxide in the blood, or a pharmaceutical composition for improving blood lipids. The pharmaceutical composition contains an HMG-CoA reductase inhibitor; and gamma-oryzanol, and/or thiamines. For treatment, the components of the composition can be administered together, as a composition, or separately.Type: ApplicationFiled: January 27, 2005Publication date: August 18, 2005Applicant: SANKYO COMPANY, LIMITEDInventors: Tatsuhito Kondo, Ikuo Takagi, Masato Nakayama, Yasuhiro Torizumi
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Publication number: 20050182106Abstract: A medicinal composition for mitigating blood lipid and for reducing the amount of blood homocysteine. The medicinal composition contains an HMG-CoA reductase inhibitor and a pyridoxine compound.Type: ApplicationFiled: January 7, 2005Publication date: August 18, 2005Applicant: SANKYO COMPANY, LIMITEDInventors: Tatsuhito Kondo, Ikuo Takagi, Masato Nakayama, Yasuhiro Torizumi
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Patent number: 6916849Abstract: The present invention relates to compositions for lowering the total amount of cholesterol in the blood and methods of using the compositions. The compositions are a mixture of pravastatin and one or more vitamins selected from riboflavins, d-?-tocopherols, ascorbic acids and inositol hexanicotinate.Type: GrantFiled: May 1, 2003Date of Patent: July 12, 2005Assignee: Sankyo Company, LimitedInventors: Tsuneki Ohsawa, Ikuo Takagi, Ippei Shimizu, Tatsuhito Kondo, Masato Nakayama, Yasuhiro Torizumi
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Publication number: 20050107956Abstract: The present invention relates to a concentration measuring method which includes selecting a calibration curve optimum for computing the concentration of a measurement target substance from a plurality of calibration curves based on an output from a reaction system containing the target substance and a reactant capable of reacting with the target substance, and computing the concentration of the target substance based on the optimum calibration curve and the output. Each of the calibration curves is prepared based on a plurality of outputs generated upon lapse of a same reaction time from a plurality of standard reaction systems each containing a standard reagent of a known different concentration and the reactant. The plurality of calibration curves differ from each other in reaction time based on which the calibration curves are prepared.Type: ApplicationFiled: December 25, 2002Publication date: May 19, 2005Applicant: ARKRAY, Inc.Inventors: Satoshi Fukunaga, Masato Nakayama
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Publication number: 20040023919Abstract: A blood lipid ameliorating composition containing atorvastatin in combination with one or more members selected from a riboflavin derivative, a tocopherol compound, an ascorbic acid derivative, pantethine and taurine.Type: ApplicationFiled: June 11, 2003Publication date: February 5, 2004Applicant: SANKYO COMPANY, LIMITEDInventors: Tsuneki Ohsawa, Ikuo Takagi, Ippei Shimizu, Tatsuhito Kondo, Masato Nakayama, Yasuhiro Torizumi
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Publication number: 20040014712Abstract: A blood lipid ameliorating composition containing simvastatin and one or more ingredients selected from a riboflavin compound, a d-&agr;-tocopherol compound, an ascorbic acid compound, pantethine, and taurine.Type: ApplicationFiled: June 12, 2003Publication date: January 22, 2004Applicant: SANKYO COMPANY, LIMITEDInventors: Tsuneki Ohsawa, Ikuo Takagi, Ippei Shimizu, Tatsuhito Kondo, Masato Nakayama, Yasuhiro Torizumi
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Publication number: 20040009986Abstract: A blood triglyceride depressant composition which comprises pravastatin and one or more members selected from the group consisting of (1) pantethine, (2) inositol hexanicotinate, (3) a combination drug containing a riboflavin compound, a tocopherol compound and an ascorbic acid compound, and (4) a combination drug containing a tocopherol compound and an ascorbic acid compound.Type: ApplicationFiled: June 18, 2003Publication date: January 15, 2004Applicant: SANKYO COMPANY, LIMITEDInventors: Tsuneki Ohsawa, Ikuo Takagi, Ippei Shimizu, Tatsuhito Kondo, Masato Nakayama, Yasuhiro Torizumi
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Publication number: 20030229124Abstract: Compositions having excellent blood lipid peroxide lowering activity are provided. In particular, compositions for lowering lipid peroxides in the blood which contain pravastatin together with at least one substance selected from the group consisting of taurine, pantethine and inositol hexanicotinate. Use of these compositions enables the provision of excellent preventive or remedial agents capable of lowering the concentration of lipid peroxides in the blood which show effects of injuring vascular endothelial cells, accelerating platelet aggregation, forming foam cells, etc.Type: ApplicationFiled: May 2, 2003Publication date: December 11, 2003Applicant: SANKYO COMPANY, LIMITEDInventors: Tsuneki Ohsawa, Ikuo Takagi, Ippei Shimizu, Tatsuhito Kondo, Masato Nakayama, Yasuhiro Torizumi
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Publication number: 20030220343Abstract: The present invention relates to compositions for lowering the total amount of cholesterol in the blood and methods of using the compositions. The compositions are a mixture of pravastatin and one or more vitamins selected from riboflavins, d-&agr;-tocopherols, ascorbic acids and inositol hexanicotinate.Type: ApplicationFiled: May 1, 2003Publication date: November 27, 2003Applicant: SANKYO COMPANY, LIMITEDInventors: Tsuneki Ohsawa, Ikuo Takagi, Ippei Shimizu, Tatsuhito Kondo, Masato Nakayama, Yasuhiro Torizumi
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Publication number: 20030216357Abstract: The present invention relates to compositions for lowering the total amount of cholesterol in the blood and methods of using the compositions. The compositions are a mixture of pravastatin and one or more vitamins selected from riboflavins, d-&agr;-tocopherols, ascorbic acids and inositol hexanicotinate.Type: ApplicationFiled: April 22, 2003Publication date: November 20, 2003Applicant: SANKYO COMPANY, LIMITEDInventors: Tsuneki Ohsawa, Ikuo Takagi, Ippei Shimizu, Tatsuhito Kondo, Masato Nakayama, Yasuhiro Torizumi