Patents by Inventor Masato Yasui

Masato Yasui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210137452
    Abstract: A sleep determination apparatus includes a heart rate data obtainer that obtains, based on data regarding a heart rate of a body of a user, a very low frequency component (VLF), a ratio of a low frequency component (LF) to a high frequency component (HF), a mean heartbeat interval (RRI), and a standard deviation of each heartbeat interval (RRI) of the heart rate as heart rate variability parameters indicating a heart rate state; and a sleep state determiner that determines which of a plurality of sleep stages the user is in, using the heart rate variability parameters, in such a manner as to distinguish between a first non-REM sleep stage and a second non-REM sleep stage.
    Type: Application
    Filed: June 4, 2018
    Publication date: May 13, 2021
    Applicant: KEIO UNIVERSITY
    Inventors: Yasue MITSUKURA, Masato YASUI, Koichi FUKUNAGA, Toshiharu FURUKAWA
  • Patent number: 11002728
    Abstract: It is an object to provide a method for evaluating a medicinal substance targeting a G protein-coupled receptor (GPCR). Specifically, the present invention relates to a method for evaluating the activity of a GPCR comprising a step of bringing a target substance into contact with a cell expressing a GPCR on the cell membrane; and a step of determining the diffusive dynamics of the GPCR on the cell membrane.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: May 11, 2021
    Assignee: RIKEN
    Inventors: Masataka Yanagawa, Yasushi Sako, Michio Hiroshima, Masato Yasui, Masahiro Ueda, Yuichi Togashi
  • Publication number: 20210130455
    Abstract: A subject of the present invention is to provide an anti AQP3 antibody specifically recognizing the extracellular domain of aquaporin 3 (AQP3), which is one type of a water channel protein. By selecting a monoclonal antibody which specifically binds to an oligopeptide included in loop C as one of the extracellular domains of AQP3, an anti AQP3 antibody that is desired in the present invention is provided. An anti AQP3 monoclonal antibody of the present invention can directly bind, from the outside of a cell, to AQP3 present in a cell membrane. Furthermore, as an anti AQP3 monoclonal antibody of the present invention can have an inhibitory activity, the function of permeating a low molecular weight molecule or the like, which is carried by AQP3, can be suppressed.
    Type: Application
    Filed: October 12, 2018
    Publication date: May 6, 2021
    Applicant: Keio University
    Inventors: Mariko Chikuma, Masato Yasui
  • Publication number: 20210041659
    Abstract: An autofocus device includes a stage, a magnifying optical system, a light source device, an iris which is arranged at a position opposite to a sample of the magnifying optical system and configured to limit a light beam emitted from the light source device, and an AF camera which receives, via the magnifying optical system, a reflected light beam which is reflected from a reflection surface after the light beam reaches a glass member via the iris and the magnifying optical system. The light source device emits the light beam at a non-zero angle relative to the axis of the magnifying optical system. The control unit adjusts the position of the stage so as to match the position of a captured image of a shield with a target position. With such a configuration, it is possible to achieve the autofocus at high speed.
    Type: Application
    Filed: January 24, 2019
    Publication date: February 11, 2021
    Inventors: Masato YASUI, Michio HIROSHIMA, Masahiro UEDA
  • Publication number: 20180306779
    Abstract: It is an object to provide a method for evaluating a medicinal substance targeting a G protein-coupled receptor (GPCR). Specifically, the present invention relates to a method for evaluating the activity of a GPCR comprising a step of bringing a target substance into contact with a cell expressing a GPCR on the cell membrane; and a step of determining the diffusive dynamics of the GPCR on the cell membrane.
    Type: Application
    Filed: April 19, 2018
    Publication date: October 25, 2018
    Inventors: Masataka YANAGAWA, Yasushi SAKO, Michio HIROSHIMA, Masato YASUI, Masahiro UEDA, Yuichi TOGASHI
  • Patent number: 9709555
    Abstract: Provided are a compound that generates an SHG signal but has suppressed generation of a TPF signal. Also provided is a cell examination method using the same. A compound for generating a second harmonic of light, the compound being an azobenzene derivative of formula (1), or a salt thereof. (R1 and R2 independently represent alkyl groups having 6-12 carbon atoms, and R3 to R18 independently represent substituents selected from hydrogen, halogens, alkyl groups, alkoxy groups, aryl groups, amino groups, hydroxyl groups, nitro groups, and cyano groups, but R5 and R6, R9 and R10, R13 and R14, and R17 and R18 may combine together and form a ring structure having 5-7 carbon atoms. X represents —N+R19R20R21, a sulfonyl group, a carboxyl group, or an —OR group. Here, R19, R20, and R21 independently represent straight-chain or branched alkyl groups having 1-5 carbon atoms, and —OR represents a monovalent polyalkylene oxide group terminated by an alkoxy group. a is 0 or 1, b is 0 or 1, and n is an integer of 1-10.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: July 18, 2017
    Assignee: KEIO UNIVERSITY
    Inventors: Mutsuo Nuriya, Masato Yasui, Tatsuo Arai, Atsuya Momotake, Syun Fukushima
  • Publication number: 20160116460
    Abstract: Provided are a compound that generates an SHG signal but has suppressed generation of a TPF signal. Also provided is a cell examination method using the same. A compound for generating a second harmonic of light, the compound being an azobenzene derivative of formula (1), or a salt thereof. (R1 and R2 independently represent alkyl groups having 6-12 carbon atoms, and R3 to R18 independently represent substituents selected from hydrogen, halogens, alkyl groups, alkoxy groups, aryl groups, amino groups, hydroxyl groups, nitro groups, and cyano groups, but R5 and R6, R9 and R10, R13 and R14, and R17 and R18 may combine together and form a ring structure having 5-7 carbon atoms. X represents —N+R19R20R21, a sulfonyl group, a carboxyl group, or an —OR group. Here, R19, R20, and R21 independently represent straight-chain or branched alkyl groups having 1-5 carbon atoms, and —OR represents a monovalent polyalkylene oxide group terminated by an alkoxy group. a is 0 or 1, b is 0 or 1, and n is an integer of 1-10.
    Type: Application
    Filed: May 23, 2014
    Publication date: April 28, 2016
    Inventors: Mutsuo NURIYA, Masato YASUI, Tatsuo ARAI, Atsuya MOMOTAKE, Syun FUKUSHIMA
  • Patent number: 5845174
    Abstract: An image forming apparatus equipped with a monochrome mode and color mode, in which the transfer drum is made to rotate without any paper wrapped around it to clean the transfer drum each time a series of copy operations is completed. By controlling the cleaning period through increasing or decreasing the number of non-paper rotations in response to the last copy operation mode, the transfer drum may be adequately cleaned at all times, and the amount of wear on the transfer drum and cleaning device caused by the cleaning operation is reduced.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: December 1, 1998
    Assignee: Minolta Co., Ltd.
    Inventors: Masato Yasui, Kazunobu Maekawa, Seiichi Munemori, Kuniaki Ishiguro
  • Patent number: 5765074
    Abstract: The present invention relates to an image forming apparatus having a first forming device forming a first toner image on a first surface of a sheet, a second forming device forming a second toner image on a second surface of the sheet, a detecting device detecting the amount of adhered toner on the first surface of the sheet, a setting device setting an forming output according to the amount of adhered toner detected by detecting device, and inputting device inputting the forming output to the second forming device in order to form the second toner image by the settled forming output. The object of the present invention is to provide a reliable image forming.
    Type: Grant
    Filed: June 24, 1996
    Date of Patent: June 9, 1998
    Assignee: Minolta Co., Ltd.
    Inventors: Masato Yasui, Kazunobu Maekawa
  • Patent number: 5666621
    Abstract: The invention relates a sheet separation apparatus including a sheet carrying member which is capable of holding a sheet thereon, a device positioning a sheet on the surface of the sheet carrying member, a device separating the held sheet from the sheet carrying member by predetermined sheet separating power, said separating means capable of changing the sheet separating power, and a device selecting sheet separating power of the separating device according with the surface of the sheet positioned by the positioning device. The object of the invention is to provide a reliable separation of the sheet from said sheet carrying member.
    Type: Grant
    Filed: June 26, 1996
    Date of Patent: September 9, 1997
    Assignee: Minolta Co., Ltd.
    Inventors: Kazunobu Maekawa, Masato Yasui