Abstract: An image processing device includes a determination unit configured to determine a type of autophagy induced in a cell, based on information indicative of autophagic activity in the cell present in a cell image in which the cell is image captured and based on information indicative of congestion of molecules in the cell present in the cell image.

Abstract: A laminate including a metal substrate having a chemically etched surface and a fluoroelastomer layer laminated in contact with the chemically etched surface or laminated in contact with a surface of a fluororesin layer laminated in contact with the chemically etched surface, and a gate seal including the laminate, are provided.

Abstract: Provided are a laminate including a metal substrate having a surface with an anodic oxide coating formed thereon, a fluororesin layer laminated in contact with the anodic oxide coating and a fluoroelastomer layer laminated in contact with a surface of the fluororesin layer facing away from the metal substrate, and a gate seal including the laminate.

Abstract: A laminate including a metal substrate having a chemically etched surface and a fluoroelastomer layer laminated in contact with the chemically etched surface or laminated in contact with a surface of a fluororesin layer laminated in contact with the chemically etched surface, and a gate valve including the laminate, are provided.

Abstract: An object of the present invention is to develop and provide a lung cancer differential marker with which lung cancer can be diagnosed conveniently and highly sensitively without depending only on increase or decrease in protein expression level between cancer patients and healthy persons. Another object of the present invention is to develop and provide a glycan marker capable of distinguishing histological types of lung cancer. Of serum glycoproteins, glycopeptide and glycoprotein groups whose glycan structures were altered specifically in lung cancer cell culture supernatants were identified, and they are provided as lung cancer differential markers.

Abstract: Provided are a laminate including a metal substrate having a surface with an anodic oxide coating formed thereon, a fluororesin layer laminated in contact with the anodic oxide coating and a fluoroelastomer layer laminated in contact with a surface of the fluororesin layer facing away from the metal substrate, and a gate seal including the laminate.

Abstract: A thermoplastic resin composition which includes 50% to 90% by mass of a powder material (A) and 50% to 10% by mass of a ?-olefin-based thermoplastic resin (B), wherein the ?-olefin-based thermoplastic resin (B) includes a first ?-olefin-based thermoplastic resin (B1) having an isotactic pentad fraction [mmmm] of 70% to 99% and a melting point in the range of 120° C. to 168° C., and a second ?-olefin-based thermoplastic resin (B2) having an isotactic pentad fraction [mmmm] of 30% to 60% and a melting point in the range of 60° C. to 100° C., and the mass ratio ((B2)/(B1)) of the second ?-olefin-based thermoplastic resin (B2) relative to the first ?-olefin-based thermoplastic resin (B1) is 0.3 to 2.0.

Abstract: Provided is a sheet press molding method by which a molded product having a small plate thickness deviation is obtained. Such a sheet press molding method is provided with a process in which a molded product (30) having a recess and protrusion pattern portion (32), to which a recess and protrusion pattern (3) is transferred, is formed by pressurizing a sheet-shaped material (20) including 60 vol. % to 95 vol.

Abstract: An object of the present invention is to develop and provide a lung cancer differential marker with which lung cancer can be diagnosed conveniently and highly sensitively without depending only on increase or decrease in protein expression level between cancer patients and healthy persons. Another object of the present invention is to develop and provide a glycan marker capable of distinguishing histological types of lung cancer. Of serum glycoproteins, glycopeptide and glycoprotein groups whose glycan structures were altered specifically in lung cancer cell culture supernatants were identified, and they are provided as lung cancer differential markers.

Abstract: An object of the present invention is to develop and provide a lung cancer differential marker with which lung cancer can be diagnosed conveniently and highly sensitively without depending only on increase or decrease in protein expression level between cancer patients and healthy persons. Another object of the present invention is to develop and provide a glycan marker capable of distinguishing histological types of lung cancer. Of serum glycoproteins, glycopeptide and glycoprotein groups whose glycan structures were altered specifically in lung cancer cell culture supernatants were identified, and they are provided as lung cancer differential markers.

Abstract: A pressure sensor comprising: a base film on which a conductor pattern having one or more electrodes is formed; a cover film laminated on the base film so as to cover the electrodes of the conductor pattern; and a spacer disposed between the cover film and the base film so as to form a hollow portion having a predetermined gap between the electrode and the cover film; wherein a portion corresponding to the hollow portion of the cover film is constructed such that it has a pressure sensing part which is able to deform in a direction to move toward and away from the electrode in accordance with pressure, and of which contact resistance changes in accordance with a contact pressure thereof with the electrode, so that the pressure sensing part detects the pressure by a change of the contact resistance.

Abstract: The present invention is to provide a polypeptide specifically inhibiting the activity of Akt (Protein Kinase B), the DNA thereof, the antibody thereof, an inhibitor of Akt activity or an antitumor agent, and the like. The polypeptide comprises polypeptides (SEQ ID NO: 1, 3, 5, 7, and 9 of the sequence listing) that contain an amino acid sequence corresponding to any of the position of amino acid residue 10-24 of human TCL1, amino acid residue 8-22 of human TCL1B, amino acid residue 5-19 of human MTCP1, and amino acid residue 9-24 of mouse or rat TCL1; and the derivatives. Further, the present invention includes DNA encoding the polypeptide (SEQ ID NO: 2, 4, 6, 8 or 10 of the sequence listing), and the antibodies specifically binding to the polypeptides. The polypeptide of the present invention can be used for an inhibitor of Akt activity, an antitumor agent, or the like.

Abstract: Provided are a heat-curable resin composition that yields a molded article having excellent dimensional accuracy and mechanical property even when high-temperature molding is carried out, a production method of article and a molded article thereof, a cured article, a molded article, and a separator for a fuel cell. A heat-curable resin composition in an embodiment of the present invention comprises: (A) a binder in an amount of 100 parts by mass comprising 50 mass % or more of a polymer comprising 60 mol % or more monomer units having a carbon-carbon double bond in a side chain; (B) a carbon material in an amount of 150 to 1,000 parts by mass; (C) a curing initiator in an amount of 1 to 10 parts by mass; and (D) a curing retarder in an amount of 0.1 to 2 parts by mass.

Abstract: There is provided a curable composition which can give a cured product having excellent physical properties and is particularly useful as a material for the separator of a fuel cell such as polymer electrolyte fuel cell. The electrically conducting curable resin composition of the present invention comprises (A) a hydrocarbon compound having a plurality of carbon-carbon double bonds, (B) an elastomer excluding the component (A), and (C) a carbonaceous material.

Abstract: A pressure sensor comprising: a base film on which a conductor pattern having one or more electrodes is formed; a cover film laminated on the base film so as to cover the electrodes of the conductor pattern; and a spacer disposed between the cover film and the base film so as to form a hollow portion having a predetermined gap between the electrode and the cover film; wherein a portion corresponding to the hollow portion of the cover film is constructed such that it has a pressure sensing part which is able to deform in a direction to move toward and away from the electrode in accordance with pressure, and of which contact resistance changes in accordance with a contact pressure thereof with the electrode, so that the pressure sensing part detects the pressure by a change of the contact resistance.

Abstract: A compound represented by the following general formula (I): [wherein R1 and R2 represent an alkyl group, X represents —S—, —O— or —NH—, Y represents C or N, R3 represents hydrogen atom or a C1-10 alkyl group, Z represents —CO—N(R5)— (R5 represents hydrogen atom or a C1-6 alkyl group) or —C(R6)?C(R7)—CO—NH— (R6 and R7 represent hydrogen atom or a C1-6 alkyl group), Ar represents an aryldiyl group or a heteroaryldiyl group, and R4 represents —COOH, —OCH2—COOH, —CH2—COOH, or —CH2—CH2—COOH], which has a retinoid action and is useful as an active ingredient of a medicament.

Abstract: An object of the present invention is to develop and provide a lung cancer differential marker with which lung cancer can be diagnosed conveniently and highly sensitively without depending only on increase or decrease in protein expression level between cancer patients and healthy persons. Another object of the present invention is to develop and provide a glycan marker capable of distinguishing histological types of lung cancer. Of serum glycoproteins, glycopeptide and glycoprotein groups whose glycan structures were altered specifically in lung cancer cell culture supernatants were identified, and they are provided as lung cancer differential markers.

Abstract: A metal gasket includes an outer ring that is formed in a substantially C-shaped cross-section having an opening in a circumferential direction and an inner ring that is disposed inside the outer ring, wherein the inner ring is configured in a polygonal shape of a cross section, and a pair of corner portions opposing to each other in the inner ring are disposed on inner circumferential faces on the both sides of the opening in the outer ring.

Abstract: The present invention is to provide a polypeptide specifically inhibiting the activity of Akt (Protein Kinase B), the DNA thereof, the antibody thereof, an inhibitor of Akt activity or an antitumor agent, and the like. The polypeptide comprises polypeptides (SEQ ID NO: 1, 3, 5, 7, and 9 of the sequence listing) that contain an amino acid sequence corresponding to any of the position of amino acid residue 10-24 of human TCL1, amino acid residue 8-22 of human TCL1B, amino acid residue 5-19 of human MTCP1, and amino acid residue 9-24 of mouse or rat TCL1; and the derivatives. Further, the present invention includes DNA encording the polypeptide (SEQ ID NO: 2, 4, 6, 8 or 10 of the sequence listing), and the antibodies specifically binding to the polypeptides. The polypeptide of the present invention can be used for an inhibitor of Akt activity, an antitumor agent, or the like.

Abstract: A compound represented by the following general formula (I): [wherein R1 represents hydrogen atom or a C1-6 alkyl group, A and B represent —(CH2)2—, —(CH2)3—or —(CH2)4—, X represents —N(R2)—CO—(R2 represents hydrogen atom or a C1-6 alkyl group), —CO—N(R3)—(R3 represents hydrogen atom or a C1-6 alkyl group), —C(R4)?C(R5)—(R4 and R5 represent hydrogen atom or a C1-6 alkyl group), or —N(R6)—SO2—(R6 represents hydrogen atom or a C1-6 alkyl group), and Ar represents an aryldiyl group or a heteroaryldiyl group], which has a retinoid action and is useful as an active ingredient of a medicament.