Patents by Inventor Matthew James Leoni

Matthew James Leoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180020749
    Abstract: A garment includes a connected front and back panels forming a cavity for an upper body of a subject. Each of a pair of sleeves is connected to at least one of the front or back panel and is in communication with the cavity. A collar is configured to surround a neck of the subject. Each of a pair of shoulder straps is connected at one end to the collar and at an opposing end to at least one of the front or back panels or a sleeve. A first opening is formed by at least the straps, a top edge of the front panel, and the collar to expose a top portion of the subject's chest. A second opening is formed by at least the straps, a top edge of the back panel, and the collar to expose a top portion of the subject's back.
    Type: Application
    Filed: December 29, 2015
    Publication date: January 25, 2018
    Inventors: Paul MARTINETTI, Bernadette Irene MANGIONE, Jerry Kim Leng TAN, Shannon Louise MOORE, Diane Travaglini RUDISILL, Valerie TILLIER-LEFRANCOIS, Matthew James LEONI, Michael GRAEBER, Alessandra Beatriz ALIO-SAENZ, Marie Helene PEIRONE, Jae Karlo Calandria LOPEZ, Joyce Lee HWA
  • Patent number: 9861632
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: January 9, 2018
    Assignee: Galderma Laboratories, L.P.
    Inventors: Michael Graeber, Christian Loesche, Philip Freidenreich, Yin-sang Liu, Matthew James Leoni
  • Patent number: 9861631
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: January 9, 2018
    Assignee: Galderma Laboratories, L.P.
    Inventors: Michael Graeber, Christian Loesche, Philip Freidenreich, Yin-sang Liu, Matthew James Leoni
  • Publication number: 20170296535
    Abstract: Methods and products for treating or preventing erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical aqueous gel composition comprising about 0.01% to about 10% by weight of at least one ?-adrenergic receptor agonist and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: June 28, 2017
    Publication date: October 19, 2017
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Jack A. DEJOVIN, Isabelle Jean DEJOVIN, Yin-sang LIU, Matthew James LEONI
  • Publication number: 20170216231
    Abstract: The present invention concerns a pharmaceutical composition comprising 0.3% by weight of adapalene or a pharmaceutically acceptable salt thereof and 2.5% by weight of benzoyl peroxide, as active ingredients, for its use by topical administration in the treatment of inflammatory acne lesions. The present invention further concerns regimen for the therapeutic treatment of acne lesions in subjects afflicted with severe acne. The regimen includes topically applying to a subject's skin, as active ingredients, 0.3% by weight adapalene and 2.5% by weight benzoyl peroxide, combined in a single formula that delivers the active ingredients together. The single formula can for example be applied once or twice daily for a period of 8 to 12 weeks.
    Type: Application
    Filed: July 16, 2015
    Publication date: August 3, 2017
    Inventors: Matthew James LEONI, Michael GRAEBER, Vasant MANNA
  • Publication number: 20170095434
    Abstract: The present invention concerns a pharmaceutical composition comprising 0.3% by weight of adapalene or a pharmaceutically acceptable salt thereof and 2.5% by weight of benzoyl peroxide, as active ingredients, for its use by topical administration in the treatment of inflammatory acne lesions. The present invention further concerns regimen for the therapeutic treatment of acne lesions in subjects afflicted with severe acne. The regimen includes topically applying to a subject's skin, as active ingredients, 0.3% by weight adapalene and 2.5% by weight benzoyl peroxide, combined in a single formula that delivers the active ingredients together. The single formula can for example be applied once or twice daily for a period of 8 to 12 weeks.
    Type: Application
    Filed: December 19, 2016
    Publication date: April 6, 2017
    Inventors: Matthew James LEONI, Michael GRAEBER, Vasant MANNA
  • Publication number: 20170087085
    Abstract: Methods and products for treating or preventing erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical aqueous gel composition comprising about 0.01% to about 10% by weight of at least one ?-adrenergic receptor agonist and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: December 8, 2016
    Publication date: March 30, 2017
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Jack A. DEJOVIN, Isabelle Jean DEJOVIN, Yin-sang LIU, Matthew James LEONI
  • Patent number: 9554988
    Abstract: Methods, compositions and products for preventing skin tumor formation or inhibiting the development of an existing skin tumor in a subject are described. The methods involve administering to the subject a composition containing an ? adrenergic receptor agonist, such as brimonidine.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: January 31, 2017
    Assignee: Galderma Research & Development
    Inventors: Guy Bouvier, Matthew James Leoni, Michael Graeber
  • Publication number: 20160095857
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: December 14, 2015
    Publication date: April 7, 2016
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Yin-sang LIU, Matthew James LEONI
  • Publication number: 20160008355
    Abstract: Methods and products for treating or preventing erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical aqueous gel composition comprising about 0.01% to about 10% by weight of at least one ?-adrenergic receptor agonist and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: September 23, 2015
    Publication date: January 14, 2016
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Jack A. DEJOVIN, Isabelle Jean DEJOVIN, Yin-sang LIU, Matthew James LEONI
  • Publication number: 20150313894
    Abstract: The invention relates to a method of treating erythema and/or telangiectasia associated with rosacea in a patient in need thereof by topically administering an effective amount of a combination of brimonidine or a pharmaceutically acceptable salt thereof and oxymetazoline or a pharmaceutically acceptable salt thereof to the site of erythema and/or telangiectasia on the skin of the patient. The invention further relates to topical compositions including the combination of compounds and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: July 13, 2015
    Publication date: November 5, 2015
    Inventors: Michael Graeber, Matthew James Leoni, Nathalie Wagner
  • Publication number: 20150313895
    Abstract: The invention relates to a method of treating dermatological conditions or symptoms associated therewith in a patient in need thereof by topically administering an effective amount of a combination of brimonidine or a pharmaceutically acceptable salt thereof and oxymetazoline or a pharmaceutically acceptable salt thereof to the affected area of skin on the patient. The invention further relates to topical compositions including the combination of compounds and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: July 13, 2015
    Publication date: November 5, 2015
    Inventors: Michael Graeber, Matthew James Leoni, Nathalie Wagner
  • Publication number: 20150209350
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: April 6, 2015
    Publication date: July 30, 2015
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Yin-sang LIU, Matthew James LEONI
  • Publication number: 20150098917
    Abstract: Methods, compositions and products for preventing skin tumor formation or inhibiting the development of an existing skin tumor in a subject are described. The methods involve administering to the subject a composition containing an ?2 adrenergic receptor agonist, such as brimonidine.
    Type: Application
    Filed: December 15, 2014
    Publication date: April 9, 2015
    Inventors: Guy BOUVIER, Matthew James LEONI, Michael GRAEBER
  • Patent number: 8916562
    Abstract: Improved methods and compositions for safe and effective treatment of telangiectasia or a symptom associated with telangiectasia in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: December 23, 2014
    Assignee: Galderma Research & Development SNC
    Inventors: Michael Graeber, Christian Loesche, Philip Freidenreich, Yin Liu, Matthew James Leoni
  • Patent number: 8911713
    Abstract: Methods, compositions and products for preventing skin tumor formation or inhibiting development of an existing skin tumor in a subject are described. The methods involve administering to the subject a composition containing an ?2 adrenergic receptor agonist, such brimonidine.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: December 16, 2014
    Assignee: Galderma Research & Development
    Inventors: Guy Bouvier, Matthew James Leoni, Michael Graeber
  • Publication number: 20140100232
    Abstract: The invention relates to a method of treating erythema and/or telangiectasia associated with rosacea in a patient in need thereof by topically administering an effective amount of a combination of brimonidine or a pharmaceutically acceptable salt thereof and oxymetazoline or a pharmaceutically acceptable salt thereof to the site of erythema and/or telangiectasia on the skin of the patient. The invention further relates to topical compositions including the combination of compounds and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: December 9, 2013
    Publication date: April 10, 2014
    Applicant: Galderma Laboratories Inc.
    Inventors: Michael Graeber, Matthew James Leoni, Nathalie Wagner
  • Publication number: 20140094470
    Abstract: The invention relates to a method of treating dermatological conditions or symptoms associated therewith in a patient in need thereof by topically administering an effective amount of a combination of brimonidine or a pharmaceutically acceptable salt thereof and oxymetazoline or a pharmaceutically acceptable salt thereof to the affected area of skin on the patient. The invention further relates to topical compositions including the combination of compounds and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: December 10, 2013
    Publication date: April 3, 2014
    Applicant: Galderma Laboratories Inc.
    Inventors: Michael Graeber, Matthew James Leoni, Nathalie Wagner
  • Publication number: 20140094469
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: December 5, 2013
    Publication date: April 3, 2014
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Yin-sang LIU, Matthew James LEONI
  • Patent number: D758048
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: June 7, 2016
    Assignee: Gladerma Research & Development SNC
    Inventors: Paul Martinetti, Bernadette Irene Mangione, Jerry Kim Leng Tan, Shannon Louise Moore, Diane Travaglini Rudisill, Valerie Tillier-LeFrancois, Matthew James Leoni, Michael Graeber, Alessandra Beatriz Alio-Saenz, Marie Helene Peirone, Jae Karlo Calandria Lopez, Joyce Lee Hwa