Patents by Inventor Matthew John Fuchter

Matthew John Fuchter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinazoline compounds and their use in therapy
    Patent number: 9932317
    Abstract: This invention relates to quinazoline compounds of Formula (I) which are inhibitors of the histone lysine methyltransferase (HKMTase) EZH2, and to uses of such compounds as medicaments, in particular in the treatment of a disease or disorder in which inhibition of EZH2 provides a therapeutic or prophylactic effect.
    Type: Grant
    Filed: March 19, 2013
    Date of Patent: April 3, 2018
    Assignees: Imperial Innovations Limited, Emory University
    Inventors: Robert Brown, Matthew John Fuchter, Nadine Chapman-Rothe, Nitipol Srimongkolpithak, Joachim Caron, James Snyder, Thota Ganesh, Jin Liu, Aiming Sun
  • Quinazoline Compounds And Their Use In Therapy
    Publication number: 20150057263
    Abstract: This invention relates to quinazoline compounds of Formula (I) which are inhibitors of the histone lysine methyltransferase (HKMTase) EZH2, and to uses of such compounds as medicaments, in particular in the treatment of a disease or disorder in which inhibition of EZH2 provides a therapeutic or prophylactic effect.
    Type: Application
    Filed: March 19, 2013
    Publication date: February 26, 2015
    Inventors: Robert Brown, Matthew John Fuchter, Nadine Chapman-Rothe, Nitipol Srimongkolpithak, Joachim Caron, James Synder, Thota Ganesh, Jin Liu, Aiming Sun
  • Process for preparing 5,7 diaminopyrazolo [1,5-A] pyrimidine compounds
    Patent number: 8507673
    Abstract: Processes for the preparation of certain 5,7-diaminopyrazolo[1,5-?]pyrimidine compounds comprising the reaction of a primary or secondary amine and a protected 5-halo-7-aminopyrazolo[1,5-?]pyrimidine compound in solvent system comprising water and one or more organic solvents, optionally in the presence of an exogenous base.
    Type: Grant
    Filed: June 9, 2011
    Date of Patent: August 13, 2013
    Assignees: Emory University, Imperial College of Science and Technology
    Inventors: Dennis C. Liotta, James P. Snyder, Ashutosh S. Jogalekar, Anthony G. M. Barrett, Matthew John Fuchter, Matthew J. Cook, Sebastian H. B. Kroll
  • Process for Preparing 5,7 Diaminopyrazolo [1,5-a] Pyrimidine Compounds
    Publication number: 20120041198
    Abstract: Processes for the preparation of certain 5,7-diaminopyrazolo[1,5-?]pyrimidine compounds comprising the reaction of a primary or secondary amine and a protected 5-halo-7-aminopyrazolo[1,5-?]pyrimidine compound in solvent system comprising water and one or more organic solvents, optionally in the presence of an exogenous base.
    Type: Application
    Filed: June 9, 2011
    Publication date: February 16, 2012
    Inventors: Dennis C. Liotta, James P. Snyder, Ashutosh S. Jogalekar, Anthony G.M. Barrett, Matthew John Fuchter, Matthew J. Cook, Sebastian H.B. Kroll