Patents by Inventor Matthew K. Musho
Matthew K. Musho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11255834Abstract: Test sensors, methods, and systems are described that include a first electrode pair having either two active electrodes or an inactive working electrode paired with an active counter electrode. These active electrodes are different than having an electron transfer mediator on an inactive electrode because in addition to the structural differences between an electrode directly in contact with the conductors of the test sensor verses a reagent coating, there are chemical and functional differences. The active electrodes are formed from an electrode core material including an element that loses or acquires electrons during the analysis and directly participates in the electrochemical reaction of the sample. As the active electrodes are insoluble in the sample during the analysis, an electrochemically stable potential is provided by the active electrodes that can reliably operate at higher operating potentials than conventional electron transfer mediator reagents coated on an inactive electrode.Type: GrantFiled: March 21, 2017Date of Patent: February 22, 2022Assignee: Conductive Technologies, Inc.Inventors: Matthew K. Musho, Christina A. Beaverson, Nicholas F. Szabo
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Patent number: 9814674Abstract: A method of forming a kit containing multiple dissolvable unit dose constructs includes providing at least one muco-adhesive composition comprising a polymer matrix, the polymer matrix comprising a water soluble polymer, an active ingredient and a liquid carrier; forming a plurality of dissolvable thin film unit dose constructs by depositing the at least one composition onto a substrate wherein at least two adjacent dissolvable thin film unit dose constructs are formed having a pre-determined different identifiable physical characteristic with respect to the other as a result of the depositing; and packaging the plurality of dissolvable thin films in a single package to form a kit.Type: GrantFiled: May 22, 2017Date of Patent: November 14, 2017Assignee: ARX, LLCInventors: Matthew K. Musho, John H. Lind, Scott D. Barnhart
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Publication number: 20170285016Abstract: Test sensors, methods, and systems are described that include a first electrode pair having either two active electrodes or an inactive working electrode paired with an active counter electrode. These active electrodes are different than having an electron transfer mediator on an inactive electrode because in addition to the structural differences between an electrode directly in contact with the conductors of the test sensor verses a reagent coating, there are chemical and functional differences. The active electrodes are formed from an electrode core material including an element that loses or acquires electrons during the analysis and directly participates in the electrochemical reaction of the sample. As the active electrodes are insoluble in the sample during the analysis, an electrochemically stable potential is provided by the active electrodes that can reliably operate at higher operating potentials than conventional electron transfer mediator reagents coated on an inactive electrode.Type: ApplicationFiled: March 21, 2017Publication date: October 5, 2017Applicant: Conductive Technologies, Inc.Inventors: Matthew K. Musho, Christina A. Beaverson, Nicholas F. Szabo
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Publication number: 20170252294Abstract: A method of forming a kit containing multiple dissolvable unit dose constructs includes providing at least one muco-adhesive composition comprising a polymer matrix, the polymer matrix comprising a water soluble polymer, an active ingredient and a liquid carrier; forming a plurality of dissolvable thin film unit dose constructs by depositing the at least one composition onto a substrate wherein at least two adjacent dissolvable thin film unit dose constructs are formed having a pre-determined different identifiable physical characteristic with respect to the other as a result of the depositing; and packaging the plurality of dissolvable thin films in a single package to form a kit.Type: ApplicationFiled: May 22, 2017Publication date: September 7, 2017Inventors: Matthew K. MUSHO, John H. LIND, Scott D. BARNHART
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Publication number: 20170246108Abstract: Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose construct is formed by providing a first composition including a water soluble polymer and a liquid carrier, depositing the first composition onto a substrate, providing a second composition including a water soluble polymer and a liquid carrier, applying the second composition at a discrete location overlying the first composition by microdeposition; and removing at least a portion of the liquid carrier from the first composition to form the unit dose construct.Type: ApplicationFiled: May 17, 2017Publication date: August 31, 2017Inventors: Matthew K. Musho, John H. Lind, Scott D. Barnhart
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Patent number: 9662301Abstract: Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose constructs are formed of a composition including a polymer matrix that includes a water soluble polymer, active ingredient, and a liquid carrier. The composition is deposited directly, such as by stenciling, to form individual unit doses without the need to cut and convert long, continuous rolls of film.Type: GrantFiled: December 7, 2016Date of Patent: May 30, 2017Assignee: ARX, LLCInventors: Matthew K. Musho, John H. Lind, Scott D. Barnhart
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Patent number: 9662297Abstract: Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose constructs are formed of a composition including a polymer matrix that includes a water soluble polymer, active ingredient, and a liquid carrier. The composition is deposited directly, such as by stenciling, to form individual unit doses without the need to cut and convert long, continuous rolls of film.Type: GrantFiled: December 7, 2016Date of Patent: May 30, 2017Assignee: ARX, LLCInventors: Matthew K. Musho, John H. Lind, Scott D. Barnhart
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Publication number: 20170087084Abstract: Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose constructs are formed of a composition including a polymer matrix that includes a water soluble polymer, active ingredient, and a liquid carrier. The composition is deposited directly, such as by stenciling, to form individual unit doses without the need to cut and convert long, continuous rolls of film.Type: ApplicationFiled: December 7, 2016Publication date: March 30, 2017Inventors: Matthew K. MUSHO, John H. LIND, Scott D. BARNHART
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Publication number: 20170087097Abstract: Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose constructs are formed of a composition including a polymer matrix that includes a water soluble polymer, active ingredient, and a liquid carrier. The composition is deposited directly, such as by stenciling, to form individual unit doses without the need to cut and convert long, continuous rolls of film.Type: ApplicationFiled: December 7, 2016Publication date: March 30, 2017Inventors: Matthew K. MUSHO, John H. LIND, Scott D. BARNHART
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Patent number: 9545376Abstract: Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose constructs are formed of a composition including a polymer matrix that includes a water soluble polymer, active ingredient, and a liquid carrier. The composition is deposited directly, such as by stenciling, to form individual unit doses without the need to cut and convert long, continuous rolls of film.Type: GrantFiled: January 23, 2014Date of Patent: January 17, 2017Assignee: ARx, LLCInventors: Matthew K. Musho, John H. Lind, Scott D. Barnhart
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Publication number: 20140262833Abstract: A sensor having a bifurcated flow path and method for using the same is disclosed. In some embodiments, the sensor has two flow channels into which sample flow is induced by capillary action, wherein the flow channels are in contact with electrodes configured to generate an electrochemical reaction in the flow channels which can be measured and correlated to the level of an analyte in the sample. In some embodiments, the levels of more than one analyte can be measured using a single sensor.Type: ApplicationFiled: March 14, 2013Publication date: September 18, 2014Applicant: MAGELLAN DIAGNOSTICS, INC.Inventors: Matthew K. Musho, Mohammad Hossein Maleknia
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Publication number: 20140203480Abstract: Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose constructs are formed of a composition including a polymer matrix that includes a water soluble polymer, active ingredient, and a liquid carrier. The composition is deposited directly, such as by stenciling, to form individual unit doses without the need to cut and convert long, continuous rolls of film.Type: ApplicationFiled: January 23, 2014Publication date: July 24, 2014Applicant: ARx, LLCInventors: Matthew K. MUSHO, John H. LIND, Scott D. BARNHART
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Patent number: 8529742Abstract: An electrochemical sensor includes a dielectric substrate and a conductive layer formed on a surface of the substrate. The conductive layer includes a working electrode, an electrode lead and a connecting arm connecting the working electrode to the electrode lead. A dielectric layer is positioned over the conductive layer. The dielectric layer has an aperture exposing the working electrode and a portion of the connecting arm. The working electrode, electrode lead and connecting arm may be formed by laser ablation technique to provide precise working electrode sensor parameters.Type: GrantFiled: February 24, 2010Date of Patent: September 10, 2013Inventors: Matthew K. Musho, Nicholas F. Szabo
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Publication number: 20110203926Abstract: An electrochemical sensor includes a dielectric substrate and a conductive layer formed on a surface of the substrate. The conductive layer includes a working electrode, an electrode lead and a connecting arm connecting the working electrode to the electrode lead. A dielectric layer is positioned over the conductive layer. The dielectric layer has an aperture exposing the working electrode and a portion of the connecting arm. The working electrode, electrode lead and connecting arm may be formed by laser ablation technique to provide precise working electrode sensor parameters.Type: ApplicationFiled: February 24, 2010Publication date: August 25, 2011Applicant: CONDUCTIVE TECHNOLOGIES, INC.Inventors: Matthew K. Musho, Nicholas F. Szabo
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Patent number: 7911215Abstract: A test system for taking a sample of a constituent on a surface utilizing a fluid source includes a transition region having a capillary layer for delivering a fluid from said fluid source, an extraction region having a collection material in contact with said surface, and a collection region having a sensor reservoir therein for collecting the fluid for analysis.Type: GrantFiled: July 14, 2008Date of Patent: March 22, 2011Assignee: Innovative Productivity, Inc.Inventors: Paul Gossen, Jayant Angal, Matthew K. Musho, Joseph E. Yates
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Publication number: 20090015273Abstract: A test system for taking a sample of a constituent on a surface utilizing a fluid source includes a transition region having a capillary layer for delivering a fluid from said fluid source, an extraction region having a collection material in contact with said surface, and a collection region having a sensor reservoir therein for collecting the fluid for analysis.Type: ApplicationFiled: July 14, 2008Publication date: January 15, 2009Inventors: Paul Gossen, Jayant Angal, Matthew K. Musho, Joseph E. Yates
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Patent number: 7125481Abstract: An electrochemical test sensor adapted to assist in determining the concentration of analyte in a fluid sample is disclosed. The sensor comprises a base that assists in forming an opening for introducing the fluid sample, a working electrode being coupled to the base, and a counter electrode being coupled to the base, the counter electrode and the working electrode being adapted to be in electrical communication with a detector of electrical current, and a sub-element being coupled to the base. A major portion of the counter electrode is located downstream relative to the opening and at least a portion of the working electrode. The sub-element is located upstream relative to the working electrode such that when electrical communication occurs between only the sub-element and the working electrode there is insufficient flow of electrical current through the detector to determine the concentration of the analyte in the fluid sample.Type: GrantFiled: June 9, 2004Date of Patent: October 24, 2006Assignee: Bayer HealthCare LLCInventors: Matthew K. Musho, J. Oakey Noell, Andrew J. Edelbrock, Dijia Huang
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Patent number: 7118668Abstract: Disclosed is an electrochemical sensor for the determination of analytes in body fluids, e.g. glucose in blood. The sensor involves a non-conductive base which provides a flow path for the body fluid with the base having a working and counter electrode on its surface which are in electrical communication with a detector of current. The base and a cover therefore provide a capillary space containing the electrodes into which the body fluid is drawn by capillary action. The counter electrode has a sub-element which contains an electroactive material and is configured in the system (sensor and meter) to provide an error signal when insufficient body fluid is drawn into the capillary.Type: GrantFiled: November 1, 2004Date of Patent: October 10, 2006Assignee: Bayer HealthCare LLCInventors: Andrew J. Edelbrock, Matthew K. Musho, Mark S. Vreeke
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Patent number: RE44521Abstract: An electrochemical test sensor adapted to assist in determining the concentration of analyte in a fluid sample is disclosed. The sensor comprises a base that assists in forming an opening for introducing the fluid sample, a working electrode being coupled to the base, and a counter electrode being coupled to the base, the counter electrode and the working electrode being adapted to be in electrical communication with a detector of electrical current, and a sub-element being coupled to the base. A major portion of the counter electrode is located downstream relative to the opening and at least a portion of the working electrode. The sub-element is located upstream relative to the working electrode such that when electrical communication occurs between only the sub-element and the working electrode there is insufficient flow of electrical current through the detector to determine the concentration of the analyte in the fluid sample.Type: GrantFiled: October 23, 2008Date of Patent: October 8, 2013Assignee: Bayer HealthCare LLCInventors: Matthew K. Musho, J. Oakey Noell, Andrew J. Edelbrock, Dijia Huang
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Patent number: RE45384Abstract: An electrochemical test sensor adapted to assist in determining the concentration of analyte in a fluid sample is disclosed. The sensor comprises a base that assists in forming an opening for introducing the fluid sample, a working electrode being coupled to the base, and a counter electrode being coupled to the base, the counter electrode and the working electrode being adapted to be in electrical communication with a detector of electrical current, and a sub-element being coupled to the base. A major portion of the counter electrode is located downstream relative to the opening and at least a portion of the working electrode. The sub-element is located upstream relative to the working electrode such that when electrical communication occurs between only the sub-element and the working electrode there is insufficient flow of electrical current through the detector to determine the concentration of the analyte in the fluid sample.Type: GrantFiled: September 9, 2013Date of Patent: February 24, 2015Assignee: Bayer HealthCare LLCInventors: Matthew K. Musho, J. Oakey Noell, Andrew J. Edelbrock, Dijia Huang