Abstract: Techniques for managing a collaborative data management and deployment platform and generating customizable blueprints for a data deployment program are disclosed. Techniques include receiving one or more parameters for generating the blueprint for the program, receiving a selection of one or more blueprint components satisfying the one or more parameters, and generating the blueprint template as a function of the selected components. In addition, one or more data sets for use in a program are obtained. A selection of the blueprint template is received. Objects of the selected blueprint are mapped to the one or more data sets. The selected blueprint is mapped to one or more third-party data channels.

Abstract: The invention relates to compounds of the formula 1 or a pharmaceutically acceptable salt, prodrug, solvate or hydrate thereof, wherein L, R1, R2, R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating abnormal cell growth, such as cancer in a mammal by administering the compounds of formula 1.

Abstract: The invention relates to compounds of the formula 1 or a pharmaceutically acceptable salt, prodrug or hydrates thereof, wherein X, L, R1, R2, R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula 1.

Abstract: The present invention 10 discloses a workout bench 26 having a plurality of incline adjustments and stanchions with means for receiving dumbbell weights 12. The dumbbell stanchion comprises a tubular structure 16 having a base portion 38 extending transversely to its distal ends, forming vertical stanchions. The vertical stanchions 16 comprise a weight rest stanchion 18 with weight rest 19 that is slidably adjustable having apertures 22 linearly arranged in conjunction with a locking pin 24 provided on the main vertical stanchions. The bench comprises two cushions 28 fixedly attached to individual frame structures 30 each hingedly 32 connected at the center. At the other distal end of the cushion frame 30 are collapsible leg supports 34 that fold up allowing the cushions 28 to rest on the floor's surface at an angle from the pivot point. Also disclosed are internal extendable braces 42 for raising the cushions 28.

Abstract: The invention relates to compounds of the formula 1 or a pharmaceutically acceptable salt, prodrug or hydrates thereof, wherein Q, A, L, R1, R2 and R3 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula 1.

Abstract: Described is a method of handling automated conversations by categorizing a plurality of events which occur during automated conversations based on an impact of the events on a level of user satisfaction with the automated conversations, assigning to each category of events a quality score corresponding to the impact on user satisfaction of the events in each category and initiating a conversation handling action for one of the conversations based on the categories of events detected during the one of the conversations.

Abstract: The invention relates to compounds of the formula 1 or a pharmaceutically acceptable salt, prodrug, solvate or hydrate thereof, wherein L, R1, R2 R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating abnormal cell growth, such as cancer in a mammal by administering the compounds of formula 1.

Abstract: The invention relates to compounds of the formulas 1 and 2 and to prodrugs thereof, pharmaceutically acceptable salts or solvates of said compounds or said prodrugs, wherein X, R1 and R11 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formulas 1 and 2 and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formulas 1 and 2.

Abstract: The invention relates to compounds of the formula 1 wherein X1, X2 and X3 independently is a halogen; p is an integer from 1 to 3; and R is —COOH, OR1 wherein R1 is a substituted isothiazole ring, or SR2 wherein R2 is (CH2)qC(COOH)(NHC(O)R3) wherein q is an integer from 0 to 3, and R3 is (C1-C4)alkyl; and to pharmaceutically acceptable salts, prodrugs and solvates thereof. The invention also relates to methods of treating a hyperproliferative disorder in a mammal by administering the compounds of formula 1 and to pharmaceutical compositions containing the compounds of formula 1.

Abstract: The invention relates to compounds of the formula 1 or a pharmaceutically acceptable salt, prodrug or hydrates thereof, wherein X, L, R1, R2, R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula 1.

Abstract: The invention relates to compounds of the formula 1 or a pharmaceutically acceptable salt, prodrug or hydrates thereof, wherein Q, A, L, R1, R2 and R3 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula 1.

Abstract: The invention relates to compounds of the formulas 1 and 2 and to prodrugs thereof, pharmaceutically acceptable salts or solvates of said compounds or said prodrugs, wherein X, R1 and R11 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formulas 1 and 2 and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formulas 1 and 2.