Abstract: A kit including topical pharmaceutical composition of corticosteroid(s) and metered-dose dispenser with an actuator which delivers precise amount of corticosteroid(s) per actuation for the treatment of various skin disorders is disclosed. Also disclosed is a process for preparation of such compositions.

Abstract: A kit including topical pharmaceutical composition of corticosteroid(s) and metered-dose dispenser with an actuator which delivers precise amount of corticosteroid(s) per actuation for the treatment of various skin disorders is disclosed. Also disclosed is a process for preparation of such compositions.

Abstract: A refrigerator appliance including a cabinet defining a chilled chamber and a first slide assembly is provided. The first slide assembly is mounted to the cabinet at least partially within the chilled chamber. The refrigerator appliance also includes a door with a frame having a first frame member rotatably attached to the first slide assembly at a first pivot joint. The door is rotatable about the lateral direction at the first pivot joint between an inwardly tilted position and an outwardly tilted position. In the inwardly tilted position the door defines an acute angle with the first slide assembly, and in the outwardly tilted position the door defines an obtuse angle with the first slide assembly. Such a configuration may allow the door to form a more complete seal with the cabinet of the refrigerator appliance despite any, e.g., surface variations of the cabinet.

Abstract: A secondary loop temperature control circuit for a temperature-controlled region in a compartment of a refrigerator is shown. The secondary loop temperature control circuit has a reservoir, configured to have a medium flow there through. A first heat exchanger is in flow communication with the reservoir and is configured to have the medium flow there through. The first heat exchanger is in thermal communication with the temperature-controlled region.

Abstract: An ice making apparatus for a refrigerator is disclosed. The apparatus includes an ice making compartment; an icemaker disposed in the ice making compartment and including an ice mold body, the ice mold body defining therein a plurality of ice cavities for containing water therein for freezing into ice cubes, and a channel for transport of a working medium, the channel having an outlet; and a temperature sensor disposed in the ice making compartment and adjacent the outlet.

Abstract: A refrigerator is provided with a casing in the form of a shell that defines an internal storage compartment, such as a freezer or fresh-food section. A door is configured on the casing to provide access to the storage compartment, with the door closing on front edges of the casing. A hinge assembly connects the door to the casing and includes a hinge bracket having an insert end that extends through one of the front edges, for example the top front edge, and is fixed to an internal surface of the casing. The hinge bracket has an opposite end that is rotationally connected to the door for hinged support of the door on the casing.

Abstract: A refrigerator includes a body portion having an air supply and an air return, a door hinged to the body portion, and an icemaking unit located on the door and having an air inlet and an air outlet. The air inlet and air outlet are adjacent the air supply and air return, respectively, when the door is closed, to receive and return chilled air therefrom and thereto. At least a first sealing member is located at the air supply, the air return, the air inlet, and/or the air outlet. The at least first sealing member includes a first membrane with a slit formed therein, and a first projecting member. The slit and the first projecting member are configured and dimensioned such that the slit is closed when the door is in an open position and that the slit is opened when the door is in a closed position.

Abstract: A method of forming ice in a refrigerator is disclosed. The method includes cooling a first storage compartment to a first temperature, cooling a second storage compartment to a second temperature, cooling an interior volume defined in a door to a third temperature, wherein the door permits and impedes access to the second storage compartment, operating a fan disposed in the interior volume to circulate cool air through the interior volume, and cooling water to form ice in the interior volume.

Abstract: An automatic icemaker for a refrigerator is disclosed. The automatic icemaker includes an ice mold body having a front side, a back side, and a plurality of ice chambers for containing water therein for freezing into ice cubes, each ice chamber having a top opening having a frontal portion adjacent the front side; an ice stripper disposed along the front side and extending over the ice chambers, the ice stripper being configured to completely cover the frontal portion of the top opening of each ice chamber; and an ice rake disposed between the front side and the back side, the ice rake including a rotatable shaft, and a plurality of rake fingers extending outward from the shaft for moving ice cubes out of the respective ice chambers and onto the ice stripper.

Abstract: A method for cooling an icemaker is disclosed. The icemaker includes an ice mold body having a channel for transport of coolant and a plurality of ice cavities. The method includes the steps of injecting a coolant into the channel, adding water to the ice cavities, forming ice cubes in the ice cavities, removing coolant from the channel, heating the ice mold body, and ejecting the ice cubes from the ice mold body. The removal step is performed by reversing direction of a coolant pump.

Abstract: An in-door fluid drainage system for a refrigerator is disclosed. The drain fluid transfer system is described as extending from the door of a refrigerator to the lower compartment for transfer of drain fluid from the door to a drain fluid removal system. Also described is a drain fluid transfer system which comprises one or both of a transfer tube at least partially enclosed in a hinge assembly, and a valve assembly positioned at the lower portion of the door.

Abstract: Disclosed herein is a method of using megestrol acetate. In one embodiment, the method comprises informing a user that megestrol acetate is metabolized by a cytochrome p450 isozyme. In another embodiment, the method comprises obtaining megestrol acetate from a container associated with published material providing information is metabolized by a cytochrome p450 siozyme. Also disclosed are articles of manufacture comprising a container containing a dosage form of megestrol acetate, wherein the container is associated with published material informing that megestrol acetate is metabolized by a cytochrome p450 siozyme, a method of treatment, and a method of manufacturing a megestrol acetate product.

Abstract: A method of controlling temperature for forming ice within an icemaker compartment of a refrigerator is disclosed. The method includes the steps of activating at least one of the compressor and the coolant pump during an icemaking cycle to provide cooling to the icemaker compartment sufficient to make ice at a first rate, and increasing operation of at least one of the compressor and the coolant pump to provide cooling to the icemaker compartment sufficient to make ice at a second rate, which is faster than the first rate. A related refrigerator is also disclosed.

Abstract: A refrigerator includes a body portion having an air supply and an air return, a door hinged to the body portion, and an icemaking unit located on the door and having an air inlet and an air outlet. The air inlet and air outlet are adjacent the air supply and air return, respectively, when the door is closed, to receive and return chilled air therefrom and thereto. At least a first sealing member is located at the air supply, the air return, the air inlet, and/or the air outlet. The at least first sealing member includes a first membrane with a slit formed therein, and a first projecting member. The slit and the first projecting member are configured and dimensioned such that the slit is closed when the door is in an open position and that the slit is opened when the door is in a closed position.

Abstract: Top hinge-weight loaded refrigerator doors are provided. A refrigerator apparatus is provided that includes a body portion; and at least one door hinged to the body portion using at least one top hinge. The top hinge is a weight load bearing hinge.

Abstract: A refrigerator is provided with a casing in the form of a shell that defines an internal storage compartment, such as a freezer or fresh-food section. A door is configured on the casing to provide access to the storage compartment, with the door closing on front edges of the casing. A hinge assembly connects the door to the casing and includes a hinge bracket having an insert end that extends through one of the front edges, for example the top front edge, and is fixed to an internal surface of the casing. The hinge bracket has an opposite end that is rotationally connected to the door for hinged support of the door on the casing.

Abstract: A French-style refrigerator door is disclosed. The refrigerator door includes an actuator and a mullion bar rotatably mounted to the door. The mullion bar is responsive to the actuator to automatically rotate from a first position to a second position upon actuation of the actuator.

Abstract: A hinge assembly and a refrigerator using the assembly are disclosed. The assembly rotatably mounts an access door for a compartment of the refrigerator to part of refrigerator that defines the compartment. The hinge assembly has a body coupled to the part and a hinge manifold supported by the body and slidably received in the access door. The manifold has a first supply conduit for supplying a working medium to an icemaker disposed in the access door and a first return conduit for returning the working medium from the icemaker. The hinge assembly can be manufactured as a separate module to be assembled with the refrigerator or retrofit into an existing refrigerator.

Abstract: Disclosed herein is a method of using megestrol acetate. In one embodiment, the method comprises informing a user that megestrol acetate is metabolized by a cytochrome p450 isozyme. In another embodiment, the method comprises obtaining megestrol acetate from a container associated with published material providing information is metabolized by a cytochrome p450 siozyme. Also disclosed are articles of manufacture comprising a container containing a dosage form of megestrol acetate, wherein the container is associated with published material informing that megestrol acetate is metabolized by a cytochrome p450 siozyme, a method of treatment, and a method of manufacturing a megestrol acetate product.

Abstract: A secondary loop temperature control circuit for a temperature-controlled region in a compartment of a refrigerator is shown. The secondary loop temperature control circuit has a reservoir, configured to have a medium flow there through. A first heat exchanger is in flow communication with the reservoir and is configured to have the medium flow there through. The first heat exchanger is in thermal communication with the temperature-controlled region.