Patents by Inventor Matti Siren

Matti Siren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160074421
    Abstract: Diseases caused by haemorrhagic viruses, such as the Ebola and Marburg viruses, can be treated by the administration of compounds comprising a high density negatively charged domain of vicinally oriented radicals. A method of treatment, a pharmaceutical composition, and a nutritional composition are disclosed.
    Type: Application
    Filed: September 11, 2015
    Publication date: March 17, 2016
    Inventors: MATTI SIRÈN, Pontus GALLEN-KALLELA SIRÈN
  • Publication number: 20100261682
    Abstract: The present invention relates to the treatment of cachexia in a mammal by the use of a compound comprising a high density negatively charged domain of vicinally oriented radicals.
    Type: Application
    Filed: September 17, 2008
    Publication date: October 14, 2010
    Inventors: Matti Sirén, Pontus Gallen-Kallela-Sirén
  • Publication number: 20090175924
    Abstract: A method of implanting a stent whereby the risk of restenosis is reduced, the method including the step of implanting into a patient susceptible to post-implant restenosis a stent coated with a therapeutically effective amount of a compound for reducing the onset or severity of restenosis, the compound containing a high density, negatively charged domain of at least three vicinally oriented phosphorus-containing radicals.
    Type: Application
    Filed: March 16, 2009
    Publication date: July 9, 2009
    Applicant: BIONERIS AB
    Inventor: Matti Siren
  • Publication number: 20050261756
    Abstract: The invention relates to an improved construction of a coated surgical stent with a compound containing a high density, negatively charged domain of at least three vicinally oriented phosphorous-containing radicals, such device being defined as an object used for example to hold open blood vessels dilated by angioplasty, particularly coronary blood vessels, iliac aretrias and the alike and which device are utilized to widen blood vessels or other orifices in the body and which compound is preventing restenosis.
    Type: Application
    Filed: September 2, 2003
    Publication date: November 24, 2005
    Applicant: Bioneris AB
    Inventor: Matti Siren
  • Publication number: 20050227946
    Abstract: The present invention relates to a method of treating inflammatory, tissue repair and infectious conditions in a mammal suffering therefrom which comprises administering to a mammal in need thereof an effective amount of a cyclic compound selected from the group consisting of cyclopentane, cyclohexane, cycloheptane, monosaccharide.
    Type: Application
    Filed: August 7, 2003
    Publication date: October 13, 2005
    Applicant: PERSTORP AB
    Inventor: Matti Siren
  • Patent number: 6949517
    Abstract: The present invention relates to a method of treating inflammatory, tissue repair and infectious conditions in a mammal suffering therefrom which comprises administering to a mammal in need thereof an effective amount of a cyclic compound selected from the group consisting of cyclopentane, cyclohexane, cycloheptane, monosaccharide, disaccharide, triaccharide, tetrasaccharide, piperidine, tetrahydrothiopyrian, 5-oxotetrahydrothiopyran, 5,5-dioxotetrahydrothiopyran, tetrahydroselenopyran, tetrahydrofuran, pyrrolidine, tetrahydrothiophene, 5-oxotetrahydrothiophere, 5,5-dioxotetrahydrothiophene, tetrahydroselenophene, benzene, cumene, mesitylene, naphthalene and phenanthrene, in which said cyclic compound is substituted by at least three vicinal phosphorus containing radicals of the formula:
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: September 27, 2005
    Inventor: Matti Siren
  • Patent number: 6632797
    Abstract: The present invention relates to a method of treating angiogenesis in tumor conditions in a mammal suffering therefrom which comprises administering to a mammal in need thereof an effective amount of a cyclic compound selected from the group consisting of cyclopentane, cyclohexane, cycloheptane, monosaccharide, disaccharide, trisaccharide, tetrasaccharide, piperidine, tetrahydrothiopyran, 5-oxotetrahydrothiopyran, 5,5-dioxotetrahydrothiopyran, tetrahydroselenopyran, tetrahydrofuran, pyrrolidine, tetrahydrothiophene, 5-oxotetrahydrothiophene, 5,5-dioxotetrahydrothiophene, tetrahydroselenophene, benzene, cumene, mesitylene, naphthalene and phenanthrene, in which said cyclic compound is substituted by at least three vicinal phosphorus containing radicals of the formula: The present application is also directed to the use of these compounds for treating inflammatory conditions, tissue repair conditions and/or infectious conditions in a mammal.
    Type: Grant
    Filed: June 7, 2001
    Date of Patent: October 14, 2003
    Inventor: Matti Siren
  • Publication number: 20020065253
    Abstract: The present invention relates to a method of treating angiogenesis in tumor conditions in a mammal suffering therefrom which comprises administering to a mammal in need thereof an effective amount of a cyclic compound selected from the group consisting of cyclopentane, cyclohexane, cycloheptane, monosaccharide, disaccharide, trisaccharide, tetrasaccharide, piperidine, tetrahydrothiopyran, 5-oxotetrahydrothiopyran, 5,5-dioxotetrahydrothiopyran, tetrahydroselenopyran, tetrahydrofuran, pyrrolidine, tetrahydrothiophene, 5-oxotetrahydrothiophene, 5,5-dioxotetrahydrothiophene, tetrahydroselenophene, benzene, cumene, mesitylene, naphthalene and phenanthrene, in which said cyclic compound is substituted by at least three vicinal phosphorus containing radicals of the formula: 1
    Type: Application
    Filed: June 7, 2001
    Publication date: May 30, 2002
    Inventor: Matti Siren
  • Patent number: 6153603
    Abstract: The present invention relates to a method of treating angiogenesis in tumor tissue, such as glioma and glioblastama tissue. The method comprises administering to a mammal, including, man an effective amount at an isomer of inositol trisphosphate, such as D-myo-inositol-1,2,6-trisphosphate, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: May 22, 1998
    Date of Patent: November 28, 2000
    Assignee: Perstorp AB
    Inventor: Matti Siren
  • Patent number: 5846957
    Abstract: The present invention relates to the use of an ester of inositoltrispbosphate for the preparing of a medicament effective against retroviral diseases.
    Type: Grant
    Filed: May 21, 1996
    Date of Patent: December 8, 1998
    Assignee: Perstorp AB
    Inventor: Matti Siren
  • Patent number: 5654280
    Abstract: A pharmaceutical composition comprising a pharmaceutically active ingredient selected from the group consisting of trisphosphorylated pentoses, pentitols or anhydropentitols, trisphosphorylated hexoses, hexitols or anhydrohexitols and trisphosphorylated heptoses, heptitols or anhydroheptitols. The active ingredient can also be present in the form of a salt. The invention also includes a method of preventing or alleviating tissue damage in mammals, including man. The method comprises administering an effective amount of the pharmaceutical composition.
    Type: Grant
    Filed: January 17, 1995
    Date of Patent: August 5, 1997
    Assignee: Perstorp AB
    Inventor: Matti Siren
  • Patent number: 5407924
    Abstract: A method of preventing or alleviating pain by administering to a human or other mammal in need thereof of a pain preventing or alleviating effective amount of a pharmaceutical composition comprising at least one specific isomer of inositol triphosphate.
    Type: Grant
    Filed: December 1, 1993
    Date of Patent: April 18, 1995
    Assignee: Perstorp AB
    Inventor: Matti Siren
  • Patent number: 5342832
    Abstract: A method of preventing or alleviating tissue damage, diabetes and complications thereof, bone disorders, disorders related to transplantation, disorders related to abnormal levels of lipoproteins, cardiovascular disease and inflammatory disorders by providing a mammal having one or more of the above diseases with a preventing or an alleviating effective amount of a compound having the formula C.sub.6 H.sub.6 (OH).sub.6-n (OPO.sub.3 H.sub.2).sub.n, where n is an integer of 1 or 2.
    Type: Grant
    Filed: August 21, 1992
    Date of Patent: August 30, 1994
    Assignee: Perstorp AB
    Inventor: Matti Siren
  • Patent number: 5330979
    Abstract: A method of preventing or alleviating renal disorders by administering to a human or an animal in need thereof a pharmaceutical composition comprising an effective amount amount of at least one specific isomer of inositol trisphosphate sufficient to obtain said prevention or alleviation.
    Type: Grant
    Filed: June 18, 1992
    Date of Patent: July 19, 1994
    Assignee: Perstorp AB
    Inventors: Matti Siren, Bertil Lofkvist, Lars Edvinsson
  • Patent number: 5284839
    Abstract: The present invention relates to the use of inositoltrisphosphate (IP.sub.3) for the preparing of a medicament effective as a neuropeptide Y- (NPY-) antagonist and to a pharmaceutical composition comprising at least one specific isomer of IP.sub.3 and a pharmaceutically active compound effective in the cardiovascular, renal and/or cerebral area.
    Type: Grant
    Filed: February 11, 1993
    Date of Patent: February 8, 1994
    Assignee: Perstorp AB
    Inventors: Matti Siren, Lars Edvinsson
  • Patent number: 5278332
    Abstract: New derivatives of cyclohexane in substantially pure form suitable as pharmaceutical, foodstuff or as a stabilizer.
    Type: Grant
    Filed: August 5, 1992
    Date of Patent: January 11, 1994
    Assignee: Perstorp AB
    Inventors: Matti Siren, Lars Perrson
  • Patent number: 5274161
    Abstract: New derivatives of cyclohexane in substantially pure form suitable as a pharmaceutical, foodstuff or as a stabilizer.
    Type: Grant
    Filed: August 5, 1992
    Date of Patent: December 28, 1993
    Assignee: Perstorp AB
    Inventors: Matti Siren, Lars Perrson
  • Patent number: 5157140
    Abstract: New derivatives of cyclohexane in substantially pure form suitable as a pharmaceutical, foodstuff or as a stabilizer.
    Type: Grant
    Filed: December 29, 1989
    Date of Patent: October 20, 1992
    Assignee: Perstorp AB
    Inventor: Matti Siren
  • Patent number: 5135923
    Abstract: A method of reducing the negative effect of cadmium or aluminum ion or free-radicals in body tissues and a method of alleviating cardiovascular diseases and conditions by administering to a human or an animal a pharmaceutical composition comprising an amount of at least one specific isomer of inositol triphosphate sufficient to obtain said alleviation.
    Type: Grant
    Filed: February 1, 1991
    Date of Patent: August 4, 1992
    Assignee: Perstorp AB
    Inventor: Matti Siren
  • Patent number: 5128332
    Abstract: A method of preventing or alleviating certain conditions by administering to a human or an animal a pharmaceutical composition comprising an amount of at least one specific isomer of inositol trisphosphate sufficient to obtain said prevention or alleviation.
    Type: Grant
    Filed: September 11, 1990
    Date of Patent: July 7, 1992
    Assignee: Perstorp AB
    Inventors: Matti Siren, Bertil Lofkvist, Lars Edvinsson