Patents by Inventor Maxim Abashin

Maxim Abashin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240011086
    Abstract: A sensor having a first electrode and a second electrode operably connected by a conduction channel, wherein a polymerase, primed template nucleic acid and nucleotide form a stabilized ternary complex that is immobilized in or on the conduction channel, whereby association and dissociation of the ternary complex is detected due to changes in electrical properties of the sensor. Identification of the nucleotide type that participates in the complex indicates the identity of the next template base in the template. Repeated cycles of extending the primer and detecting stabilized ternary complexes can allow determination of the sequence of nucleotides for the template.
    Type: Application
    Filed: September 10, 2019
    Publication date: January 11, 2024
    Applicant: OMNIOME, INC.
    Inventors: Maxim ABASHIN, Pinar IYIDOGAN, John T. MURPHY, Alex NEMIROSKI, Min-Jui Richard SHEN, Michele Elizabeth WISNIEWSKI
  • Patent number: 11644406
    Abstract: An apparatus for evaluating focus, including (a) a stage configured to hold a specimen; and (b) an optical train including a radiation source, calibration optic, objective and detector, the optical train forming a first path wherein radiation from the radiation source is directed to the calibration optic and then a first portion of the radiation is directed to the detector, thereby forming a first image on the detector, wherein a second portion of the radiation follows a second path from the calibration optic then through the objective to the specimen, wherein the optical train forms a third path wherein radiation reflected from the specimen is transmitted through the objective, then to the detector, thereby forming a second image on the detector, and wherein the radiation that forms the first image is astigmatic.
    Type: Grant
    Filed: June 11, 2020
    Date of Patent: May 9, 2023
    Assignee: PACIFIC BIOSCIENCES OF CALIFORNIA, INC.
    Inventors: Yoshinao Taketomi, Dale Buermann, Maxim Abashin, Donald V. Rosenberry
  • Publication number: 20200393353
    Abstract: An apparatus for evaluating focus, including (a) a stage configured to hold a specimen; and (b) an optical train including a radiation source, calibration optic, objective and detector, the optical train forming a first path wherein radiation from the radiation source is directed to the calibration optic and then a first portion of the radiation is directed to the detector, thereby forming a first image on the detector, wherein a second portion of the radiation follows a second path from the calibration optic then through the objective to the specimen, wherein the optical train forms a third path wherein radiation reflected from the specimen is transmitted through the objective, then to the detector, thereby forming a second image on the detector, and wherein the radiation that forms the first image is astigmatic.
    Type: Application
    Filed: June 11, 2020
    Publication date: December 17, 2020
    Applicant: Omniome, Inc.
    Inventors: Yoshinao TAKETOMI, Dale BUERMANN, Maxim ABASHIN, Donald V. ROSENBERRY
  • Patent number: 9952453
    Abstract: Techniques, systems, and devices are disclosed for implementing nanostructures in the optical domain that highly localize the incident electromagnetic field to with a large spectral range from the visible to the infrared range. An optical nano antenna device is provided to include a substrate; a central conductive core formed on the substrate; and a peripheral conductive shell formed on the substrate and located peripheral to the central conductive core to surround at least a part of the central conductive core. The central conductive core and peripheral conductive shell form a coaxial structure with a dimension less than an optical wavelength of light.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: April 24, 2018
    Assignee: The Regents of the University of California
    Inventors: Yeshaiahu Fainman, Alexei Smolyaninov, Lin Pang, Lindsay Freeman, Maxim Abashin
  • Publication number: 20170191125
    Abstract: Systems and methods for performing DNA sequencing. An example system includes a flow cell, a mechanism to generate fluid flow, a number of reservoirs for containing respective fluids, and a number valves configured such that fluid from any particular one of the plurality of reservoirs can be individually supplied to the flow cell under the impetus of the mechanism to generate fluid flow by opening of the respective valve of the particular reservoir and closing the other valves. Fluids containing test nucleotides may be sequentially flowed through the flow cell and the flow cell imaged at each step to detect binding of the test nucleotides to a sample. The nucleotide sequence of the sample is derived from the images. The sample may be arrayed on a sensing surface of a prism, and the images may be obtained, for example, by surface plasmon resonance imaging (SPRi) of the sensing surface or other techniques.
    Type: Application
    Filed: December 28, 2016
    Publication date: July 6, 2017
    Applicant: Omniome, Inc.
    Inventors: Kandaswamy Vijayan, Maxim Abashin, Yi Zhang, Espir Kahatt, Kerry Wilson
  • Publication number: 20170010483
    Abstract: Techniques, systems, and devices are disclosed for implementing nanostructures in the optical domain that highly localize the incident electromagnetic field to with a large spectral range from the visible to the infrared range. An optical nano antenna device is provided to include a substrate; a central conductive core formed on the substrate; and a peripheral conductive shell formed on the substrate and located peripheral to the central conductive core to surround at least a part of the central conductive core. The central conductive core and peripheral conductive shell form a coaxial structure with a dimension less than an optical wavelength of light.
    Type: Application
    Filed: June 10, 2016
    Publication date: January 12, 2017
    Inventors: Yeshaiahu Fainman, Alexei Smolyaninov, Lin Pang, Lindsay Freeman, Maxim Abashin