Patents by Inventor MERSANA THERAPEUTICS, INC.

MERSANA THERAPEUTICS, INC. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130109817
    Abstract: A modified polymer is provided herein, the modified polymer having the following formula: in which W1, W2, W3, W4, W5, W6, Z1, Z2, Z3, Z4, Z5, Z9?, R1, R2, R3, R4, R5, n1, n2, n3, n4, n5, and n6? are defined herein. The modified polymer is useful for delivering a polynucleotide to the cytoplasm of a selected tissue type or cell type.
    Type: Application
    Filed: January 7, 2013
    Publication date: May 2, 2013
    Applicant: MERSANA THERAPEUTICS, INC.
    Inventor: MERSANA THERAPEUTICS, INC.
  • Publication number: 20130101546
    Abstract: A drug conjugate is provided herein. The conjugate comprises a protein based recognition-molecule (PBRM) and a polymeric carrier substituted with one or more -LD-D, the protein based recognition-molecule being connected to the polymeric carrier by LP. Each occurrence of D is independently a therapeutic agent having a molecular weight?5 kDa. LD and LP are linkers connecting the therapeutic agent and PBRM to the polymeric carrier respectively. Also disclosed are polymeric scaffolds useful for conjugating with a PBRM to form a polymer-drug-PBRM conjugate described herein, compositions comprising the conjugates, methods of their preparation, and methods of treating various disorders with the conjugates or their compositions.
    Type: Application
    Filed: December 10, 2012
    Publication date: April 25, 2013
    Applicant: MERSANA THERAPEUTICS, INC.
    Inventor: MERSANA THERAPEUTICS, INC.