Abstract: A method for removing one or more objects or materials from a body lumen includes delivering a tube and an expandable device to the body lumen to a position proximal to the one or more objects or materials. The expandable device is positioned with a lumen of the tube, and the expandable device includes a lumen extending from a distal portion to a proximal portion. The method further includes proximally retracting the tube such that the expandable device remains in the position proximal to the one or more objects or materials, distally advancing the expandable device such that the distal portion of the expandable device at least partially surrounds the one or more objects or materials, at least partially closing a distal end of the expandable device, and moving the expandable device proximally to remove the expandable device and the one or more objects or materials from the lumen.

Abstract: The present disclosure provides a tissue debridement device and describes an example treatment for ANP using the tissue debridement device. The tissue debridement device has a sheath, a distal tip, and a plurality of rotating tines coupled to the distal tip and the sheath. The distal tip can be adjusted to be closer or further from the sheath to change a diameter of the rotating tines, thereby changing a cutting diameter of the tissue debridement device.

Abstract: One example of an internet protocol (IP) keyboard, video, mouse (KVM) device includes a universal serial bus, a display port, a network port, and a processor. The USB port is to be communicatively coupled to a host device. The display port is to be communicatively coupled to the host device. The network port is to be communicatively coupled to a network. The processor is communicatively coupled to the USB port, the display port, and the network port. The processor is to receive, via the display port, a multi-stream transport (MST) DisplayPort signal; demux the MST DisplayPort signal to provide a plurality of individual video streams; and output, via the network port, each individual video stream.

Abstract: A system for providing a solar harvesting building envelope is disclosed. The system includes a plurality of solar harvesting apparatus configured to be installed as or on a building envelope in a manner like that of traditional shingles or siding. The apparatus includes a frame having a photovoltaic end wall, and reflective base and side walls. A translucent, wedge-shaped body layer is positioned on the frame. A luminescent species film is positioned at and substantially parallel to a base of the wedge-shaped body layer, such that the luminescent species film is positioned at an angle relative to the photovoltaic end wall. Light incident on the wedge-shaped body layer is concentrated towards the photovoltaic end wall, such as through absorption and re-emission along with scattering by the luminescent species film and internal reflection by the wedge-shaped body layer and the reflective base and side walls of the frame.

Abstract: An aerosolizable material is provided. The aerosolizable material comprises at least one cannabinoid and at least one carrier constituent, wherein the material does no comprise a surface active constitute. Methods of making the aerosolizable material and articles comprising the aerosolizable material are also provided.

Abstract: An image presentation system for an amusement park includes a first display with an opening extending therethrough, wherein at least a portion of the first display is viewable from a viewing area, a movable arm, wherein the movable arm is positioned within the opening, a second display supported by the movable arm and offset from the first display, wherein the second display conceals the opening from the viewing area, and a controller configured to provide a first image via the first display and a second image via the second display such that the second image comprises an image effect that accounts for the offset and coordinates with the first image to present as though the first image and the second image are a single image displayed by the first display.

Abstract: Apparatus operative via executable software to quantify building metrics using artificial intelligence analysis of a design plan. A design plan is represented using multiple dynamic components. Each dynamic component may include a parameter changeable via the user interactive interface. The dynamic components may be arranged in a user interactive interface to form a first set of boundaries, including a respective length and area, and defining at least a portion of a first unit. AI is used to determine a longest path of egress and a supportable occupancy load that may be used to determine compliance with parameters of a given code. The AI may assess whether a building described in the design plans complies with a relevant code set forth by an authority having jurisdiction. Codes may include, for example, codes enforcing fire safety and the Americans with Disabilities Act.

Abstract: A cannulation device is adapted to gain access to the patient's common bile duct. In some instances, the cannulation device includes a first guidewire lumen extending through an elongate shaft and terminating at a first oblique guidewire port, and a second guidewire lumen extending through the elongate shaft and terminating at a second oblique guidewire port. In some instances, the cannulation device includes an inflatable balloon that is inflatable from a collapsed configuration to an expanded configuration in which the inflatable balloon is adapted to occlude the patient's pancreatic duct. In some instances, the cannulation device includes an expandable element that is expandable from a collapsed configuration in which the expandable element is disposed within the guidewire lumen and an extended configuration in which a portion of the expandable element extends distally from a guidewire port.

Abstract: A pulsed-laser applies short (e.g., less than 10 pico-seconds) pulses to modify quantum particle (e.g., alkali-metal and alkaline-earth-metal atoms) ultra-high vacuum (UHV) cells to bond, ablate, and/or chemically modify vacuum-facing surfaces of the cell. The pulses are generated outside the cell and are transmitted through a vacuum-boundary wall. In one example, one vacuum-boundary wall is first contact bonded to other vacuum boundary walls at a relatively low temperature (below 200° C.), sufficient to form a temporary hermetic seal. Pulsed laser bonding is used to reinforce the contact bonds, correcting defects and generally increasing the robustness of the seal. The pulses provide high peak power to ensure strong bonds, but low total heat so as to avoid heat damage to nearby cell components and to limit quantum-particle sorbtion to and into cell walls.

Abstract: The present disclosure provides compositions that enable sustained release of a small molecule tyrosine kinase inhibitor, such as axitinib from a bioerodible polyester polymer implant for the treatment of disease. The composition is especially suitable for treating ophthalmic indications, such as neovascular age related macular degeneration and diabetic macular edema, by intravitreal injection of the implant. The implant is designed to be pre-loaded into a small diameter needle and injected via self-sealing scleral needle penetration at the pars plana. Small molecule tyrosine kinase inhibitors may be released from the implants over a period of one week to three years.

Abstract: The present invention relates to methods for the synthesis of conjugates useful for the treatment of viral infections, e.g., conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir or an analog thereof) linked to an Fc domain monomer.

Abstract: In an aspect, a system for monitoring a battery system in-flight. The system includes at least a battery pack and a pack monitoring unit (PMU) communicatively connected with a battery pack. The battery pack includes a plurality of battery packs. The PMU may include at least a sensor and a controller. At least a sensor is configured to detect battery datum. A controller is communicatively connected with at least a sensor. A controller is configured to receive battery datum, detect a significant event as a function of battery datum, and transmit the significant event to a remote device.

Abstract: A machine direction (MD) position profile measurement of a moving sheet records the MD position of each of the cross direction (CD) measurements. A sheet monitoring system includes means for measuring the MD speed of the sheet of material; means for associating measured MD speed with time to generate time-associated MD speeds; means for recording the time-associated MD speeds; a first scanning sensor for measuring a first characteristic of the sheet material wherein the first scanning sensor is located at a first position along the MD and the first scanner sensor traverses back and forth along a CD; and means for associating first characteristic measurements with time to generate time-associated first characteristic measurements. Single and multiple scanning sensors can be employed. For multiple scanner systems where the scanners are synchronized, the technique enables recreation of the real zig-zag measurement path and same spot measurements.

Abstract: A system for disconnecting a battery from an electric aircraft upon impact. The system includes an electric aircraft and a battery assembly electrically coupled to the electric aircraft. The battery assembly is configured to include at least a sensor. The at least a sensor is configured to detect impacts to the electric aircraft. The battery assembly is configured to include a connector. The connector attaches the battery assembly to the electric aircraft. The connector includes an electrically actuating disconnection mechanism. The battery assembly is configured to include a control circuit. The control circuit is electrically connected to the electrically actuating disconnection mechanism. The control circuit is configured to detect, using the at least a sensor, an impact to the aircraft. The control sensor disconnects the connector from the electric aircraft using the electrically actuating disconnection mechanism as a function of the detection of impacts to the electric aircraft.

Abstract: A process for manufacturing custom optically active quantum-particle cells includes forming a pre-customization assembly and then, in response to receipt of specifications for quantum-particle cells, performing a customization subprocess on the pre-customization assembly to yield custom quantum-particle cells, e.g., vapor cells, vacuum cells, micro-channel cells containing alkali metal or alkaline-earth metal ions or neutral atoms. The customization can include for metasurface structures on cell walls, e.g., to serve as anti-reflection coatings, lenses, etc., and introducing quantum particles (e.g., alkali metal atoms). A cover can be bonded to hermetically seal the assembly, which can then be diced to yield plural separated custom optically active quantum-particle cells.

Abstract: The present invention relates to echinocandin cyclopeptides and to methods for preparing echinocandin cyclopeptides.

Abstract: The present invention relates to intermediates and methods for synthesizing protein-drug conjugates that can be used for the treatment of diseases and related conditions.

Abstract: Provided in this disclosure are components and methods for diagnostic and communication for an electric aircraft. Components may include a diagnostic element connected to a flight component which may include a sensor and a diagnostic circuit. Component may detect a module datum, maintenance phenomenon, maintenance datum, and flight status. Flight status may be transmitted to a remote device accessible by a user.

Abstract: A vacuum cell is described. The vacuum cell includes an inner chamber, a buffer channel, and a buffer ion pump. The buffer channel is fluidically isolated from the inner chamber and fluidically isolated from an ambient external to the vacuum cell. The buffer ion pump is fluidically coupled to the buffer channel and fluidically isolated from the ambient and the inner chamber.

Abstract: In an aspect of the present disclosure is a system for locking a battery for an electric aircraft, the system including a battery pack including a high voltage (HV) connection configured to electrically connect to the electric aircraft; and a lock attached to the battery pack and configured to electrically disconnect the battery pack from the electric aircraft when locked, wherein the lock is configured to only be unlocked manually.