Patents by Inventor Michael Dolberg Rasmussen

Michael Dolberg Rasmussen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for increasing gene copy number in a host cell and resulting host cell
    Patent number: 6762040
    Abstract: The invention relates to a method for increasing the copy number of a chromosomally integrated expression cassette in a microbial strain without leaving antibiotic resistance markers behind in the strain, the necessary genetic constructs, and the strains resulting from the method of the invention.
    Type: Grant
    Filed: July 5, 2001
    Date of Patent: July 13, 2004
    Assignee: Novozymes A/S
    Inventor: Michael Dolberg Rasmussen
  • Method for increasing gene copy number in a host cell and resulting host cell
    Publication number: 20030044940
    Abstract: The invention relates to a method for increasing the copy number of a chromosomally integrated expression cassette in a microbial strain without leaving antibiotic resistance markers behind in the strain, the necessary genetic constructs, and the strains resulting from the method of the invention.
    Type: Application
    Filed: July 5, 2001
    Publication date: March 6, 2003
    Inventor: Michael Dolberg Rasmussen
  • In vivo recombination
    Patent number: 6326206
    Abstract: The present invention relates to a method for in vivo recombination of homologous DNA sequences. The method is a forced artificial evolution resulting in a DNA sequence encoding a polypeptide having an advantageous property.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: December 4, 2001
    Assignee: Novozymes A/S
    Inventors: Mads Eskelund Bjornvad, Michael Dolberg Rasmussen, Per Lina Jorgensen, Torben Vedel Borchert, Stanislas Dusko Ehrlich
  • Process and composition for desizing cellulosic fabric with an enzyme hybrid
    Patent number: 6017751
    Abstract: Cellulose-containing fabric is desized by treating with an enzyme hybrid having a catalytically active amino acid sequence of an enzyme such as a lipase or an amylase linked to an amino acid sequence containing a cellulose-binding domain. The enzyme amino acid sequence may be of an .alpha.-amylase obtainable from a species of Bacillus such as Bacillus licheniformis, or of a lipase obtainable from a species of Humicola, Candida, Pseudomonas or Bacillus. The cellulose-binding domain may be from a cellulase, a xylanase, a mannanase, an arabinofuranosidase, an acetylesterase or a chitinase. The enzyme hybrid is obtained from a transformed host cell containing an expression cassette having a DNA sequence encoding the enzyme hybrid. A desizing composition is formed containing the enzyme hybrid and a wetting agent.
    Type: Grant
    Filed: March 6, 1997
    Date of Patent: January 25, 2000
    Assignee: Novo Nordisk A/S
    Inventors: Claus von der Osten, Mads E. Bjornvad, Jesper Vind, Michael Dolberg Rasmussen
  • Process for removal or bleaching of soiling or stains from cellulosic fabric
    Patent number: 6015783
    Abstract: The present invention relates to a process for removal or bleaching of soiling or stains present on cellulosic fabric, wherein the fabric is contacted in aqueous medium with a modified enzyme (enzyme hybrid) which comprises a catalytically active amino acid sequence of a non-cellulolytic enzyme linked to an amino acid sequence comprising a cellulose-binding domain. The invention further relates to a detergent composition comprising an enzyme hybrid of the type in question and a surfactant, and to a process for washing soiled or stained cellulosic fabric, wherein the fabric is washed in an aqueous medium to which is added such a detergent composition.
    Type: Grant
    Filed: March 6, 1997
    Date of Patent: January 18, 2000
    Assignee: Novo Nordisk A/S
    Inventors: Claus von der Osten, Joel R. Cherry, Mads E. Bjornvad, Jesper Vind, Michael Dolberg Rasmussen
  • DNA constructs and methods of producing xylose isomerase
    Patent number: 5935837
    Abstract: The present invention relates xylose isomerases obtainable from strains of Thermotoga. More specifically the invention provides DNA sequences encoding xylose isomerases, expression vectors and host cells comprising the DNA sequences of the invention, and methods of producing xylose isomerases. The invention also provides isolated xylose isomerases free from homologous impurities and obtained by the method of the invention.
    Type: Grant
    Filed: July 28, 1997
    Date of Patent: August 10, 1999
    Assignee: Novo Nordisk A/S
    Inventor: Michael Dolberg Rasmussen
  • Alkaline bacillus amylase
    Patent number: 5856164
    Abstract: An .alpha.-amylase characterized by having a specific activity at least 25% higher than the specific activity of Termamyl.RTM. at a temperature in the range of 25.degree. C. to 55.degree. C. and at a pH value in the range of pH 8 to pH 10.
    Type: Grant
    Filed: May 22, 1997
    Date of Patent: January 5, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Henrik Bisg.ang.rd-Frantzen, Peter Rahbek stergaard, Michael Dolberg Rasmussen, Pia Van Der Zee
  • Alkaline bacilus amylase
    Patent number: 5824531
    Abstract: An .alpha.-amylase characterized by having a specific activity at least 25% higher than the specific activity of Termamyl.RTM. at a temperature in the range of 25.degree. C. to 55.degree. C. and a pH value in the range of pH 8 to pH 10.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: October 20, 1998
    Assignee: Novid Nordisk
    Inventors: Helle Outtrup, Henrik Bisg.ang.rd-Frantzen, Peter Rahbek stergaard, Michael Dolberg Rasmussen, Pia Van der Zee