Patents by Inventor Michael F. Bradley

Michael F. Bradley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hexa-, hepta-, and octapeptides having antiangiogenic activity
    Patent number: 7122625
    Abstract: Compounds of formula (SEQ ID NO:1), which are useful for treating conditions that arise from or are exacerbated by angiogenesis, are described. Also disclosed are pharmaceutical compositions comprising these compounds, methods of treatment using these compounds, and methods of inhibiting angiogenesis.
    Type: Grant
    Filed: October 30, 2002
    Date of Patent: October 17, 2006
    Assignee: Abbott Laboratories
    Inventors: Fortuna Haviv, Michael F. Bradley
  • Hepta-, Octa-and nonapeptides having antiangiogenic activity
    Patent number: 7067490
    Abstract: Compounds of formula (SEQ ID NO:1), which are useful for treating conditions that arise from or are exacerbated by angiogenesis, are described. Also disclosed are pharmaceutical compositions comprising these compounds, methods of treatment using these compounds, and methods of inhibiting angiogenesis.
    Type: Grant
    Filed: October 30, 2002
    Date of Patent: June 27, 2006
    Assignee: Abbott Laboratories
    Inventors: Fortuna Haviv, Michael F. Bradley
  • TRI-, TETRA-, and penta-peptides having antiangiogenic activity
    Patent number: 7037897
    Abstract: Compounds of formula (SEQ ID NO:1), which are useful for treating conditions that arise from or are exacerbated by angiogenesis, are described. Also disclosed are pharmaceutical compositions comprising these compounds, methods of treatment using these compounds, and methods of inhibiting angiogenesis.
    Type: Grant
    Filed: October 30, 2002
    Date of Patent: May 2, 2006
    Assignee: Abbott Laboratories
    Inventors: Fortuna Haviv, Michael F. Bradley
  • Di-, tri-, and tetra-peptides having antiangiogenic activity
    Patent number: 7001984
    Abstract: Compounds having the formula (SEQ ID NO:1), which are useful for treating conditions that arise from or are exacerbated by angiogenesis, are described. Also disclosed are pharmaceutical compositions comprising these compounds, methods of treatment using these compounds, and methods of inhibiting angiogenesis.
    Type: Grant
    Filed: October 30, 2002
    Date of Patent: February 21, 2006
    Assignee: Abbott Laboratories
    Inventors: Fortuna Haviv, Michael F. Bradley
  • N-alkylated peptides having antiangiogenic activity
    Patent number: 6777535
    Abstract: N-Alkylated peptides of formula (I) Xaa1-Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-Xaa8-Xaa9-Xaa10-Xaa11  (I), are useful for inhibiting angiogenesis. Also disclosed are angiogenesis-inhibiting compositions and methods of inhibiting angiogenesis in a mammal.
    Type: Grant
    Filed: October 31, 2000
    Date of Patent: August 17, 2004
    Assignee: Abbott Laboratories
    Inventors: Fortuna Haviv, Jack Henkin, Douglas M. Kalvin, Michael F. Bradley
  • Peptide antiangiogenic drugs
    Patent number: 6774211
    Abstract: Peptides having the formula: A0-A1-A2-A3-A4-A5-A6-A7-A8-A9-A10 wherein A0 is selected from hydrogen or an acyl group; A10 is a hydroxyl group or an amino acid amide; and A1, A2, A3, A4, A5, A6, A7, A8, and A9 are amino acyl residues as defined herein.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: August 10, 2004
    Assignee: Abbott Laboratories
    Inventors: Jack Henkin, Fortuna Haviv, Michael F. Bradley, Douglas M. Kalvin, Andrew J. Schneider
  • Peptides having antiangiogenic activity
    Patent number: 6753408
    Abstract: Peptides of formula (I) Xaa1-Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-Xaa8-Xaa9-Xaa10-Xaa11  (I), are useful for inhibiting angiogenesis. Also disclosed are angiogenesis-inhibiting compositions and methods of inhibiting angiogenesis in a mammal.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: June 22, 2004
    Inventors: Fortuna Haviv, Jack Henkin, Michael F. Bradley, Douglas M. Kalvin, Andrew J. Schneider
  • Method of inhibiting angiogenesis
    Publication number: 20040116479
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: October 3, 2003
    Publication date: June 17, 2004
    Inventors: Fortuna Haviv, Michael F. Bradley, Jurgen Dinges, Daryl R. Sauer, Jack Henkin
  • Method of inhibiting angiogenesis
    Publication number: 20040067985
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: October 4, 2002
    Publication date: April 8, 2004
    Inventors: Fortuna Haviv, Michael F. Bradley, Jurgen Dinges, Daryl R. Sauer, Jack Henkin
  • Peptide antiangiogenic drugs
    Patent number: 6716963
    Abstract: Peptides having the formula: A0-A1-A2-A3-A4-A5-A6-A7-A8-A9-A10 wherein A0 is selected from hydrogen or an acyl group; A10 is a hydroxyl group or an amino acid amide; and A1, A2, A3, A4, A5, A6, A7, A8, and A9 are amino acyl residues as defined herein.
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: April 6, 2004
    Assignee: Abbott Laboratories
    Inventors: Jack Henkin, Fortuna Haviv, Michael F. Bradley, Douglas M. Kalvin, Andrew J. Schneider
  • Substituted pyridines having antiangiogenic activity
    Publication number: 20040014744
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: March 12, 2003
    Publication date: January 22, 2004
    Inventors: Fortuna Haviv, Michael F. Bradley, Jack Henkin, Jurgen Dinges, Daryl R. Sauer, Lawrence Kolaczkowski, Anil Vasudevan, David C. Park
  • Octa- and nonapeptides having antiangiogenic activity
    Publication number: 20030125259
    Abstract: Compounds of formula (SEQ ID NO:1), which are useful for treating conditions that arise from or are exacerbated by angiogenesis, are described. Also disclosed are pharmaceutical compositions comprising these compounds, methods of treatment using these compounds, and methods of inhibiting angiogenesis.
    Type: Application
    Filed: October 31, 2001
    Publication date: July 3, 2003
    Inventors: Fortuna Haviv, Michael F. Bradley
  • Penta- and hexapeptides having antiangiogenic activity
    Publication number: 20030125261
    Abstract: Compounds of formula (SEQ ID NO:1), which are useful for treating conditions that arise from or are exacerbated by angiogenesis, are described. Also disclosed are pharmaceutical compositions comprising these compounds, methods of treatment using these compounds, and methods of inhibiting angiogenesis.
    Type: Application
    Filed: October 31, 2001
    Publication date: July 3, 2003
    Inventors: Fortuna Haviv, Michael F. Bradley
  • Tetra-and pentapeptides having antiangiogenic activity
    Publication number: 20030125260
    Abstract: Compounds of formula (SEQ ID NO:1), which are useful for treating conditions that arise from or are exacerbated by angiogenesis, are described. Also disclosed are pharmaceutical compositions comprising these compounds, methods of treatment using these compounds, and methods of inhibiting angiogenesis.
    Type: Application
    Filed: October 31, 2001
    Publication date: July 3, 2003
    Inventors: Fortuna Haviv, Michael F. Bradley
  • Hepta-and octapeptides having antiangiogenic activity
    Publication number: 20030119746
    Abstract: Compounds of formula (SEQ ID NO: 1), which are useful for treating conditions that arise from or are exacerbated by angiogenesis, are described. Also disclosed are pharmaceutical compositions comprising these compounds, methods of treatment using these compounds, and methods of inhibiting angiogenesis.
    Type: Application
    Filed: October 31, 2001
    Publication date: June 26, 2003
    Inventors: Fortuna Haviv, Michael F. Bradley
  • HEXA- and heptapeptides having antiangiogenic activity
    Publication number: 20030119745
    Abstract: Compounds of formula (SEQ ID NO:1), which are useful for treating conditions that arise from or are exacerbated by angiogenesis, are described. Also disclosed are pharmaceutical compositions comprising these compounds, methods of treatment using these compounds, and methods of inhibiting angiogenesis.
    Type: Application
    Filed: October 31, 2001
    Publication date: June 26, 2003
    Inventors: Fortuna Haviv, Michael F. Bradley
  • Hexa-, hepta-, and octapeptides having antiangiogenic activity
    Publication number: 20030114386
    Abstract: Compounds of formula (SEQ ID NO:1), which are useful for treating conditions that arise from or are exacerbated by angiogenesis, are described. Also disclosed are pharmaceutical compositions comprising these compounds, methods of treatment using these compounds, and methods of inhibiting angiogenesis.
    Type: Application
    Filed: October 30, 2002
    Publication date: June 19, 2003
    Inventors: Fortuna Haviv, Michael F. Bradley
  • HEPTA-, OCTA-and nonapeptides having antiangiogenic activity
    Publication number: 20030109455
    Abstract: Compounds of formula (SEQ ID NO:1), which are useful for treating conditions that arise from or are exacerbated by angiogenesis, are described. Also disclosed are pharmaceutical compositions comprising these compounds, methods of treatment using these compounds, and methods of inhibiting angiogenesis.
    Type: Application
    Filed: October 30, 2002
    Publication date: June 12, 2003
    Inventors: Fortuna Haviv, Michael F. Bradley
  • DI-, TRI-, and tetra-peptides having antiangiogenic activity
    Publication number: 20030109458
    Abstract: Compounds having the formula (SEQ ID NO: 1), which are useful for treating conditions that arise from or are exacerbated by angiogenesis, are described. Also disclosed are pharmaceutical compositions comprising these compounds, methods of treatment using these compounds, and methods of inhibiting angiogenesis.
    Type: Application
    Filed: October 30, 2002
    Publication date: June 12, 2003
    Inventors: Fortuna Haviv, Michael F. Bradley
  • TRI-, TETRA-, and penta-peptides having antiangiogenic activity
    Publication number: 20030109456
    Abstract: Compounds of formula (SEQ ID NO:1), which are useful for treating conditions that arise from or are exacerbated by angiogenesis, are described. Also disclosed are pharmaceutical compositions comprising these compounds, methods of treatment using these compounds, and methods of inhibiting angiogenesis.
    Type: Application
    Filed: October 30, 2002
    Publication date: June 12, 2003
    Inventors: Fortuna Haviv, Michael F. Bradley