Patents by Inventor Michael F. Bregen

Michael F. Bregen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5674921
    Abstract: A radiation-curable prepolymer of a polyurethane endtipped with an hydroxy (acrylate or methacrylate) is disclosed. The polyurethane is derived from the reaction of a polyfunctional isocyanate with a hydrolyzable oligomer of an anhydrous cyclic ester of an hydroxy acid. Crosslinked polymers prepared by irradiating the prepolymers are also disclosed. The crosslinked polymers are bioabsorbable and biocompatible with bodily tissue, yet still maintain the outstanding mechanical properties one would expect from a polyurethane. The prepolymers and crosslinked polymers are especially well-suited for the fabrication of surgical devices, particularly wound closure devices such as surgical staples and clips, in a stereolithography apparatus.
    Type: Grant
    Filed: February 1, 1995
    Date of Patent: October 7, 1997
    Assignee: Ethicon, Inc.
    Inventors: Donald W. Regula, Michael F. Bregen, Stuart L. Cooper, Dennis D. Jamiolkowski, Rao S. Bezwada
  • Patent number: 5550172
    Abstract: A process for enhancing the security of implantable surgical devices secured to bone tissue comprising implanting in bone tissue a surgical device with a biocompatible adhesive and/or sealant selected from the group consisting of: p1 (a) a material made from monomers of the formula:CHR.sup.1 .dbd.CX.sup.1 Y.sup.1wherein X.sup.1 and Y.sup.1 are each strong electron withdrawing groups, and R.sup.1 is hydrogen or, provided that X.sup.1 and Y.sup.1 are both cyano groups, a C.sub.1 -C.sub.4 alkyl group;(b) a semi-crystalline aliphatic poly(ester) of the formula:[--0--R.sup.11 --C(0)--].sub.y,wherein R.sup.11 is selected from the group consisting of --CR.sup.12 H--, --(CH.sub.2).sub.3 --0--, --CH.sub.2 --CH.sub.2 --O--CH.sub.2 --, CR.sub.12 H--CH.sub.2, --(CH.sub.2).sub.4 --, --(CH.sub.2).sub.z --O--C(O)-- and --(CH.sub.2).sub.z --C(O)--CH.sub.2 --; R.sup.
    Type: Grant
    Filed: February 7, 1995
    Date of Patent: August 27, 1996
    Assignee: Ethicon, Inc.
    Inventors: Donald W. Regula, Kevin Cooper, Michael F. Bregen, Shawn T. Huxel, Daniel C. Rosenman
  • Patent number: 5346501
    Abstract: A mechanism and applier therefor which is capable of inverted anastomosis of two lumens by an absorbable fastener. The fastener is made from two washer-like plate assemblies and a pair of introducers. Each such plate assembly has slots to receive latching prongs protruding from the other plate, and pins to impale tissue. Fastening is done through an applier that causes the pins to pierce the tissue, and causes a knife blade to cut through excess tissue. Fastening is done by attaching fastener halves. Insertion and removal of the fastener and applier optimally is done in an endoscopic procedure through a trocar or through the surgical incision in an open procedure. The system can be used such that the plates can be placed to properly set gaps between and anastomose tissue. The introducer portion will soften intraluminally and be expelled, in about 24 hours. The coupler portion will remain in place for 2-3 weeks, typically, and then fragment and be expelled with the feces.
    Type: Grant
    Filed: February 5, 1993
    Date of Patent: September 13, 1994
    Assignee: Ethicon, Inc.
    Inventors: Donald W. Regula, Michael F. Bregen, Zoltan Szabo, Barry N. Gardiner
  • Patent number: 5304204
    Abstract: A self-closing receiverless surgical fastener comprises a fastener body of biocompatible or bioabsorbable material including a bridge member and at least two tines extending from opposite ends of the bridge member. The tines are resiliently deformable from a normally closed position with the distal ends of the tines pointing toward each other to an open position with the distal ends of the tines extending substantially parallel to each other for penetrating into tissue. The tines are resiliently returnable to the closed position with the distal ends of the tines pointing toward each other to secure the fastener body to the tissue.
    Type: Grant
    Filed: February 9, 1993
    Date of Patent: April 19, 1994
    Assignee: Ethicon, Inc.
    Inventor: Michael F. Bregen