Patents by Inventor Michael G. Roepel

Michael G. Roepel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alpha ketoamide compounds as cysteine protease inhibitors
    Patent number: 8450373
    Abstract: The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
    Type: Grant
    Filed: July 27, 2011
    Date of Patent: May 28, 2013
    Assignee: Virobay, Inc.
    Inventors: Michael Graupe, John O. Link, Michael G. Roepel
  • ALPHA KETOAMIDE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS
    Publication number: 20120190714
    Abstract: The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
    Type: Application
    Filed: July 27, 2011
    Publication date: July 26, 2012
    Applicants: Applera Corporation, ViroBay, Inc.
    Inventors: Michael Graupe, John O. Link, Michael G. Roepel
  • Alpha ketoamide compounds as cysteine protease inhibitors
    Patent number: 8013183
    Abstract: The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: September 6, 2011
    Assignee: ViroBay, Inc.
    Inventors: Michael Graupe, John O. Link, Michael G. Roepel
  • ALPHA KETOAMIDE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS
    Publication number: 20100305331
    Abstract: The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
    Type: Application
    Filed: February 23, 2010
    Publication date: December 2, 2010
    Applicant: ViroBay, Inc.
    Inventors: Michael Graupe, John O. Link, Michael G. Roepel
  • Alpha ketoamide compounds as cysteine protease inhibitors
    Patent number: 7696250
    Abstract: The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: April 13, 2010
    Assignee: ViroBay, Inc.
    Inventors: Michael Graupe, John O. Link, Michael G. Roepel
  • ALPHA KETOAMIDE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS
    Publication number: 20090170909
    Abstract: The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
    Type: Application
    Filed: December 17, 2008
    Publication date: July 2, 2009
    Applicant: Virobay, Inc.
    Inventors: Michael Graupe, John O. Link, Michael G. Roepel
  • Alpha ketoamide compounds as cysteine protease inhibitors
    Patent number: 7488848
    Abstract: The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
    Type: Grant
    Filed: March 17, 2006
    Date of Patent: February 10, 2009
    Assignee: Virobay, Inc.
    Inventors: Michael Graupe, John O. Link, Michael G. Roepel