Patents by Inventor Michael George Berg

Michael George Berg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • U1 snRNP Regulates Gene Expression and Modulates Oncogenicity
    Publication number: 20220073917
    Abstract: The invention provides a method of regulating U1 activity associated with its splicing role as well as its role in protecting pre-mRNAs from premature termination by cleavage and polyadenylation, thereby modulating expression of a gene or genes. In one embodiment, the invention includes compositions and methods for regulating gene expression and treating diseases associated with dysregulated gene expression.
    Type: Application
    Filed: September 22, 2021
    Publication date: March 10, 2022
    Inventors: Gideon Dreyfuss, Lili Wan, Jung Min Oh, Anna Maria Pinto, Ihab Younis, Michael George Berg, Daisuke Kaida
  • U1 snRNP regulates gene expression and modulates oncogenicity
    Patent number: 11142762
    Abstract: The invention provides a method of regulating U1 activity associated with its splicing role as well as its role in protecting pre-mRNAs from premature termination by cleavage and polyadenylation, thereby modulating expression of a gene or genes. In one embodiment, the invention includes compositions and methods for regulating gene expression and treating diseases associated with dysregulated gene expression.
    Type: Grant
    Filed: July 5, 2013
    Date of Patent: October 12, 2021
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Gideon Dreyfuss, Lili Wan, Jung Min Oh, Anna Maria Pinto, Ihab Younis, Michael George Berg, Daisuke Kaida
  • U1 snRNP Regulates Gene Expression and Modulates Oncogenicity
    Publication number: 20150191724
    Abstract: The present invention relates to the discovery of a novel global gene expression regulation mechanism whereby U1 snRNP (U1) protects pre-mRNAs. In one embodiment, the invention includes compositions and methods for regulating gene expression and treating diseases associated with dysregulated gene expression.
    Type: Application
    Filed: July 5, 2013
    Publication date: July 9, 2015
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Gideon Dreyfuss, Lili Wan, Jung Min Oh, Anna Maria Pinto, Ihab Younis, Michael George Berg, Daisuke Kaida