Abstract: Embodiments of the present disclosure provide a bow and a method for reducing torque. An exemplary bow includes a riser having a pair of limbs having a string assembly operably coupled to each one of the pair of limbs, the riser with the pair of limbs operable to maintain a tension in the string assembly. The bow further includes a handle, the handle having a ball joint maintained in the handle operable to rotate relative to the handle, wherein the handle is rotatably affixed to the riser at the ball joint free floating bow including a riser having two ends, and a pair of limbs, each extending from one end of the riser.

Abstract: Disclosed herein are methods for obtaining aza-pyridone compounds, which can be useful for ameliorating and/or treating a disease and/or a condition, including an orthomyxovirus infection.

Abstract: Embodiments described herein relate generally to medical implant delivery apparatuses and methods. In some embodiments, an apparatus comprises a first cap, a needle hub at least partially disposed within the first cap, a pusher wire and a pusher wire connector disposed within the needle hub, a needle and a second cap. The first cap includes a proximal end, a distal end, and a longitudinal axis. The needle includes a first, beveled end configured to receive an implant, and a second end disposed within a hub pocket of the needle hub. The second cap is connected to the needle hub and disposed at a proximal end of the first cap. The pusher wire, the pusher wire connector, and the needle are substantially aligned with one another along the longitudinal axis of the first cap. In some embodiments, the pusher wire is sized to be received in the bore of the needle.

Abstract: An electronic apparatus for providing game-related information includes a computer processor, a memory device, a display screen, a transmitter, and a communication interface. The memory device stores at least one piece of computer code executable by the computer processor and data used by the computer code. The transmitter enables information to be communicated to a scoreboard. The communication interface enables information to be communicated to subscribers identified on a subscriber list stored in a database of the memory device. The computer code includes code for providing a user interface on the display screen to enable a scorekeeper to input an information item relating to a game, controlling the transmitter to transmit the information item to the scoreboard, controlling the memory device to store the information item in a memory therein, and controlling the communication interface to transmit the information item to at least one subscriber identified on the subscriber list.

Abstract: A detection apparatus arranged to detect defects within a flexible pipe body. The detection apparatus comprises an electrical power supply and a first meter. The electrical power supply is arranged to couple between, and to supply current to, first and second electrically conductive members extending at least partially along the length of a flexible pipe body and electrically isolated from one another except for being electrically connected at a point remote from the power supply. The first meter is arranged to detect variation between the current flowing in each electrically conductive member. Detected variation is indicative of a pipe body defect causing an Earth fault along one of the electrically conductive members. A corresponding method, a pipeline apparatus including the detection apparatus and a method of forming the pipeline apparatus are also disclosed.

Abstract: A pipeline apparatus comprising a flexible pipe body and a detection apparatus. The flexible pipe body includes an optical fiber extending at least partially along the length of the flexible pipe body, the optical fiber being encased in a metal tube. The detection apparatus comprises an optical sensor and an electrical sensor. The optical sensor is coupled to a first end of the optical fiber, the optical sensor being arranged to inject optical pulses into the optical fiber and to detect scattered or reflected light. The electrical sensor is coupled to a first end of the metal tube and to detect variation of an electrical impedance between the first end of the metal tube and a separate terminal. Variation of the scattered or reflected light, or impedance variation, is indicative of a potential pipe body defect.

Abstract: Disclosed herein are methods for obtaining aza-pyridone compounds, which can be useful for ameliorating and/or treating a disease and/or a condition, including an orthomyxovirus infection.

Abstract: A flexible pipe body comprising an elongate curvature sensor and a tensile armour layer. The elongate curvature sensor incorporates a strain sensor arranged to provide an indication of bending strain applied to the curvature sensor. The tensile armour layer comprises helically wound tensile armour wires. The curvature sensor is positioned within the tensile armour layer helically wound adjacent to at least one tensile armour wire such that bending strain applied to the flexible pipe body is transmitted to the curvature sensor. The curvature sensor is smaller than an adjacent tensile armour wire in at least one of depth and width and arranged to slide longitudinally relative to the adjacent tensile armour wire.

Abstract: Embodiments of the present disclosure provide a bow and a method for reducing torque. An exemplary bow includes a riser having a pair of limbs having a string assembly operably coupled to each one of the pair of limbs, the riser with the pair of limbs operable to maintain a tension in the string assembly. The bow further includes a handle, the handle having a ball joint maintained in the handle operable to rotate relative to the handle, wherein the handle is rotatably affixed to the riser at the ball joint free floating bow including a riser having two ends, and a pair of limbs, each extending from one end of the riser.

Abstract: A detection apparatus and method arranged to detect defects within a flexible pipe at least partially surrounded by seawater. The detection apparatus comprises a seawater electrode, an impedance monitor and a processor. The seawater electrode is arranged to be in contact with seawater surrounding at least part of a flexible pipe. The impedance monitor is arranged to measure the impedance between a metallic structural component of the flexible pipe extending at least partially along the length of the flexible pipe and the seawater electrode in response to an electrical test signal applied to the seawater electrode. The processor is arranged to determine the distance from the seawater electrode to a pipe defect electrically connecting the metallic structural component to seawater using the measured impedance.

Abstract: Disclosed herein are nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a HCV infection with one or more nucleotide analogs.

Abstract: Embodiments of the present disclosure provide a bow and a method for reducing torque. An exemplary bow includes a riser having a pair of limbs having a string assembly operably coupled to each one of the pair of limbs, the riser with the pair of limbs operable to maintain a tension in the string assembly. The bow further includes a handle, the handle having a ball joint maintained in the handle operable to rotate relative to the handle, wherein the handle is rotatably affixed to the riser at the ball joint free floating bow including a riser having two ends, and a pair of limbs, each extending from one end of the riser.

Abstract: A detection apparatus arranged to detect defects within a flexible pipe body. The detection apparatus comprises an electrical power supply and a first meter. The electrical power supply is arranged to couple between, and to supply current to, first and second electrically conductive members extending at least partially along the length of a flexible pipe body and electrically isolated from one another except for being electrically connected at a point remote from the power supply. The first meter is arranged to detect variation between the current flowing in each electrically conductive member. Detected variation is indicative of a pipe body defect causing an Earth fault along one of the electrically conductive members. A corresponding method, a pipeline apparatus including the detection apparatus and a method of forming the pipeline apparatus are also disclosed.

Abstract: A pipeline apparatus comprising a flexible pipe body and a detection apparatus. The flexible pipe body includes an optical fibre extending at least partially along the length of the flexible pipe body, the optical fibre being encased in a metal tube. The detection apparatus comprises an optical sensor and an electrical sensor. The optical sensor is coupled to a first end of the optical fibre, the optical sensor being arranged to inject optical pulses into the optical fibre and to detect scattered or reflected light. The electrical sensor is coupled to a first end of the metal tube and to detect variation of an electrical impedance between the first end of the metal tube and a separate terminal. Variation of the scattered or reflected light, or impedance variation, is indicative of a potential pipe body defect.

Abstract: An electronic apparatus for providing game-related information includes a computer processor, a memory device, a display screen, a transmitter, and a communication interface. The memory device stores at least one piece of computer code executable by the computer processor and data used by the computer code. The transmitter enables information to be communicated to a scoreboard. The communication interface enables information to be communicated to subscribers identified on a subscriber list stored in a database of the memory device. The computer code includes code for providing a user interface on the display screen to enable a scorekeeper to input an information item relating to a game, controlling the transmitter to transmit the information item to the scoreboard, controlling the memory device to store the information item in a memory therein, and controlling the communication interface to transmit the information item to at least one subscriber identified on the subscriber list.

Abstract: A system and methods using applications for entry and exit from registered locations, where a registered location has an associated geo-fence of any size or shape. A registered location may be mobile or stationary. An internet-connected device running an app transmits the current geographic location of the device, and a remote processing center executes a default action when finding correspondence between the geo-fence of a registered location and the current geographic information of an end user's device, and in one embodiment, the default action may be to enter and pay for parking at a registered location.

Abstract: Disclosed herein are nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a HCV infection with one or more nucleotide analogs.

Abstract: The present invention provides a system for fabricating a microneedle device and microneedle devices. The system includes depositing a first material on a delivery sheet, introducing the delivery sheet with deposited first material to a mold, passing the delivery sheet with deposited first material and mold through a nip-point to introduce at least a portion of first material into cavities in the mold, and separating the mold from the first material to provide a microneedle device with needles mimicking the cavities of the mold.

Abstract: A compensator designed to function with any type of base metal thermocouple which reduces the measured source impedance of high resistance thermocouples to less than 100 ohms making them compatible with or readable by modern measuring instruments.

Abstract: The present invention relates to Huwentoxin-IV variants, polynucleotides encoding them, and methods of making and using the foregoing.