Abstract: The present invention relates to multimers of polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. The invention also describes the multimerization of polypeptides through various chemical linkers and hinges of various lengths and rigidity using different sites of attachments within polypeptides. In particular, the invention describes multimers of peptides which are high affinity binders of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), particularly the spike protein S1 of SARS-CoV-2. The invention also includes pharmaceutical compositions comprising said polypeptides and to the use of said polypeptides in suppressing or treating a disease or disorder mediated by infection of SARS-CoV-2 or for providing prophylaxis to a subject at risk of infection of SARS-CoV-2.

Abstract: The present invention relates to multimers of polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. The invention also describes the multimerization of polypeptides through various chemical linkers and hinges of various lengths and rigidity using different sites of attachments within polypeptides. In particular, the invention describes multimers of peptides which are high affinity binders of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), particularly the spike protein S1 of SARS-CoV-2. The invention also includes pharmaceutical compositions comprising said polypeptides and to the use of said polypeptides in suppressing or treating a disease or disorder mediated by infection of SARS-CoV-2 or for providing prophylaxis to a subject at risk of infection of SARS-CoV-2.

Abstract: A method and apparatus for receiving nutritional information are disclosed. For example, the method receives a profile of a user, receives over the communications network, grocery information on one or more grocery items at one or more locations of the user, receives over the communications network, ingestion information on ingestion by the user of at least one grocery item from the one or more grocery items, generates nutritional information, wherein the nutritional information is determined by performing an analysis based on the profile of the user, the grocery information, and the ingestion information, and provides over the communications network, the nutritional information, to an endpoint device of the user.

Abstract: Directional environmental control provides nearly immediate comfort. A location associated with a mobile device determines an air terminal that best serves the location. Conditioned air may thus be streamed from the air terminal to the location associated with the mobile device. The conditioned air may be heated or cooled according to a profile associated with a user of the mobile device.

Abstract: A method and apparatus for receiving nutritional information are disclosed. For example, the method receives a profile of a user, receives over the communications network, grocery information on one or more grocery items at one or more locations of the user, receives over the communications network, ingestion information on ingestion by the user of at least one grocery item from the one or more grocery items, generates nutritional information, wherein the nutritional information is determined by performing an analysis based on the profile of the user, the grocery information, and the ingestion information, and provides over the communications network, the nutritional information, to an endpoint device of the user.

Abstract: Directional environmental control provides nearly immediate comfort. A location associated with a mobile device determines an air terminal that best serves the location. Conditioned air may thus be streamed from the air terminal to the location associated with the mobile device. The conditioned air may be heated or cooled according to a profile associated with a user of the mobile device.

Abstract: A method includes receiving, at a device from a first media device, audio data and image information. The audio information indicates vibrations of an object caused by sound in a vicinity of the object. The method includes generating, at the device, an audio signal based on the audio data. The method includes transmitting the audio signal from the device to a second media device conditioned upon a quality of the audio signal satisfying a threshold. Conditioned upon the quality of the audio signal failing to satisfy the threshold, the method further includes generating audio information based on the vibrations, generating audio content associated with the first media device from the audio information, and transmitting the audio content from the device to the second media device.

Abstract: Directional environmental control provides nearly immediate comfort. A location associated with a mobile device determines an air terminal that best serves the location. Conditioned air may thus be streamed from the air terminal to the location associated with the mobile device. The conditioned air may be heated or cooled according to a profile associated with a user of the mobile device.

Abstract: Directional environmental control provides nearly immediate comfort. A location associated with a mobile device determines an air terminal that best serves the location. Conditioned air may thus be streamed from the air terminal to the location associated with the mobile device. The conditioned air may be heated or cooled according to a profile associated with a user of the mobile device.

Abstract: A memory clean up mechanism may dynamically calculate the amount of free memory required and then identify a list of unused applications that may be automatically deleted to reach the required free memory.

Abstract: Directional sound location is used to determine security events of a security system. A sound sensor reports a vector direction to a sound source of an acoustic signal. If the vector direction is historically observed at similar times, then perhaps the sound source is not considered a security event. However, if the vector direction is unknown or unfamiliar, the security system may infer the security event and notify emergency services.

Abstract: Aspects of the subject disclosure may include, for example, detecting another communication device during a communication session, adjusting without interruption the communication session to add the other communication device responsive to a determination according to conferencing information that the other communication device is authorized to join in the communication session, and controlling access by the other communication device to the communication session according to user input. Other embodiments are disclosed.

Abstract: Directional sound location is used to determine security events of a security system. A sound sensor reports a vector direction to a sound source of an acoustic signal. If the vector direction is historically observed at similar times, then perhaps the sound source is not considered a security event. However, if the vector direction is unknown or unfamiliar, the security system may infer the security event and notify emergency services.

Abstract: A device, non-transitory computer-readable medium, and method for disengaging a corrective action via a wearable unit are disclosed. In one example, a processor may receive a movement model for a type of motion of a user, collect sensor data associated with the type of motion of the user from a plurality of sensors of a wearable unit, and determine that the sensor data is not in accordance with the movement model. The processor may further provide a corrective action via the wearable unit in accordance with the movement model when it is determined that the sensor data is not in accordance with the movement model, detect a triggering condition for disengaging the corrective action, and disengage the corrective action when the triggering condition is detected.

Abstract: Directional sound location is used to determine security events of a security system. A sound sensor reports a vector direction to a sound source of an acoustic signal. If the vector direction is historically observed at similar times, then perhaps the sound source is not considered a security event. However, if the vector direction is unknown or unfamiliar, the security system may infer the security event and notify emergency services.

Abstract: A method includes identifying a location of at least on of a plurality of electronic devices within an area of interest. The method includes, based on at least the location of the at least one of the plurality of electronic devices, determining signal strength at a plurality of points within the area of interest. The method includes providing a modification of the area of interest to improve the signal strength at one of the plurality of points.

Abstract: Aspects of the subject disclosure may include, for example, presenting, in a map, an interaction region associated with a user, where the interaction region is determined according to a current location, an activity, a predicted future location, and a predicted future activity of the second user, and according to a relationship between the user and another users, where the interaction region represents a geographic area in which the user is determined to be available to meet with the other user. Other embodiments are disclosed.

Abstract: A device, non-transitory computer-readable medium, and method for disengaging a corrective action via a wearable unit are disclosed. In one example, a processor may receive a movement model for a type of motion of a user, collect sensor data associated with the type of motion of the user from a plurality of sensors of a wearable unit, and determine that the sensor data is not in accordance with the movement model. The processor may further provide a corrective action via the wearable unit in accordance with the movement model when it is determined that the sensor data is not in accordance with the movement model, detect a triggering condition for disengaging the corrective action, and disengage the corrective action when the triggering condition is detected.

Abstract: Directional sound location is used to determine security events of a security system. A sound sensor reports a vector direction to a sound source of an acoustic signal. If the vector direction is historically observed at similar times, then perhaps the sound source is not considered a security event. However, if the vector direction is unknown or unfamiliar, the security system may infer the security event and notify emergency services.

Abstract: A method includes receiving, at a device from a first media device, audio data and image information. The audio information indicates vibrations of an object caused by sound in a vicinity of the object. The method includes generating, at the device, an audio signal based on the audio data. The method includes transmitting the audio signal from the device to a second media device conditioned upon a quality of the audio signal satisfying a threshold. Conditioned upon the quality of the audio signal failing to satisfy the threshold, the method further includes generating audio information based on the vibrations, generating audio content associated with the first media device from the audio information, and transmitting the audio content from the device to the second media device.